A5083537146- Tracheal and airway disorders
- Medical Imaging and Pathology Studies
- Cancer Diagnosis and Treatment
- Cardiac tumors and thrombi
- Hemoglobinopathies and Related Disorders
- Tumors and Oncological Cases
- Salivary Gland Tumors Diagnosis and Treatment
- Vascular Anomalies and Treatments
- Iron Metabolism and Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pleural and Pulmonary Diseases
- COVID-19 Clinical Research Studies
- IgG4-Related and Inflammatory Diseases
- Venous Thromboembolism Diagnosis and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Lung Cancer Diagnosis and Treatment
- Myasthenia Gravis and Thymoma
- Electrocatalysts for Energy Conversion
- SARS-CoV-2 and COVID-19 Research
- Pharmacological Effects and Toxicity Studies
- Soft tissue tumors and treatment
- Head and Neck Anomalies
- Neuroendocrine Tumor Research Advances
- Respiratory Support and Mechanisms
- Hematological disorders and diagnostics
VA Greater Los Angeles Healthcare System
2013-2024
Montefiore Medical Center
2020-2024
University of California, Los Angeles
2015-2023
Universidad de Ciencias Medicas
2022
UCLA Health
2019-2021
Albert Einstein College of Medicine
2021
West Los Angeles College
2014-2017
VA West Los Angeles Medical Center
2016
Cedars-Sinai Medical Center
2012-2013
Olive View-UCLA Medical Center
2010
The Seraph100 Microbind Affinity Blood Filter (Seraph 100) (ExThera Medical, Martinez, CA) is an extracorporeal therapy that can remove pathogens from blood, including severe acute respiratory syndrome coronavirus 2. aim of this study was to evaluate safety and efficacy Seraph 100 treatment for COVID-19.Retrospective cohort study.Nine participating ICUs.COVID-19 patients treated with (n = 53) control matched by site 53).Treatment 100.At baseline, there were no differences between the groups...
Pulmonary tumor thrombotic microangiopathy (PTTM) is a clinicopathologic disease entity in which the cells embolize to pulmonary vasculature leading series of maladaptive reactions including activation coagulation and fibrocellular intimal thickening. The resultant stenosis blood vessels leads hypertension eventual death from cor pulmonale. In this report, we present case PTTM presenting as initial manifestation metastatic gastric carcinoma young man. Although unusual its occurrence...
Pulmonary tumor thrombotic microangiopathy (PTTM) is a disease process wherein cells are thought to embolize the pulmonary circulation causing hypertension (PH) and death from right heart failure. Presented herein clinical, laboratory, radiographic, histologic features across seven cases of PTTM. Highlighted in this publication also involvement venules clinical distinguishing PTTM mimics. We conducted retrospective chart review hospitals greater Los Angeles metropolitan area. Patients series...
Boerhaave syndrome, a rare yet frequently fatal diagnosis, is characterized by the spontaneous transmural rupture of esophagus. The classic presentation syndrome Mackler's triad, consisting chest pain, vomiting, and subcutaneous emphysema. However, rarely presents with all features triad; instead, common includes or epigastric severe retching dyspnea, shock. These symptoms are typically misdiagnosed as cardiogenic in origin. Due to its atypical presentation, rarity, mimicry emergent...
Burst-suppression pattern on electroencephalography (EEG) occurs upon dissociation of the cortex from underlying brain structures. Unless is a physiologic consequence administered sedatives, this electroencephalographic indicative poor neurologic outcome and high mortality. We report case 29-year-old female thought to be dead based initial physical examination EEG findings burst-suppression, who was later found have supratherapeutic serum levels bupropion. This second documented...
Right heart thrombus in transit (RHTT) is a rare, severe form of venous thromboembolism that carries high mortality rate. The optimal treatment for RHTT has not been well established. Thrombolysis therapeutic modality but the risk bleeding complications including intracranial hemorrhage. Low-dose thrombolysis shown to be effective treating submassive pulmonary emboli without an increased complications, it studied patients with RHTT. Here, we discuss case 74-year-old male lung cancer and...
Objective The Seraph ® 100 Microbind Affinity Blood Filter (Seraph 100) is an extracorporeal medical countermeasure that can remove many pathogens from blood, including the SARS-CoV-2 virus. aim of this study was to evaluate safety and efficacy treatment for severe coronavirus disease 2019 (COVID-19). Design Multicenter retrospective observational cohort study. Setting Intensive care units across four thirteen participating sites who have completed data extraction. Patients Critically ill...
Background: The confirmation of malignant pleural effusions (MPE) requires an invasive procedure. Diagnosis can be difficult and may require repeated thoracentesis or biopsies. F18Fluorodeoxyglucose-Positron Emission Tomography (FDG-PET) characterize the extent involvement in areas increased uptake. Patterns uptake pleura sufficient to obviate need for further procedures. Methods: This is a retrospective review patients with confirmed malignancy suspected MPE. Patients who underwent...
Aspirin's antithrombotic effect is mediated predominately by inhibition of platelet cyclooxyoenase-1, leading to a decline in serum thromboxane A 2 concentrations. We performed placebo-controlled, randomized, double-blind trial determine whether aspirin could be given at 3-day intervals and still achieve potent inhibition. One hundred nine healthy men women with no recent exposure contraindications its use participated. Subjects received 325 mg, 81 or 40 mg plain every third day, placebo on...
We present 2 patients with rapidly escalating oxygen requirements from severe acute respiratory syndrome coronavirus infection (COVID-19) treated the Seraph100 Microbind Affinity Blood Filter under Emergency Use Authorization US Federal Drug Administration. The is an extracorporeal hemoperfusion filter previously demonstrated to remove viral particles and pro-inflammatory cytokines blood. Treatment was associated a rapid improvement in oxygenation both were discharged hospital without...
Epithelial-myoepithelial carcinomas are rare tumors that primarily originate in the salivary glands but have also been found tracheobronchial tree. We report first case of epithelial-myoepithelial carcinoma associated with sarcoidosis. A 61 year old Hispanic man presented altered mental status and hypercalcemia. Imaging revealed diffuse intra-thoracic intra-abdominal lymphadenopathy. diagnostic bronchoscopy was performed where an incidental tracheal nodule discovered biopsied. Pathology...
Abstract Background Ephedra and ephedrine alkaloids were commonly used in herbal supplements before being prohibited by the European Commission US Food Drug Administration. However, ongoing, unknowing use consumers can lead to potential adverse cardiovascular effects, such as arrhythmias. Case summary A 65-year-old-man with a history of idiopathic pulmonary fibrosis status post-right single lung transplant was admitted for dizziness resting tachycardia. Electrocardiogram showed narrow...
Abstract Active (acylated) ghrelin is a peptide hormone secreted primarily by the stomach, positively associated with fasting, orexigenic, and promotes growth secretion. It therefore important to energy intake management. The objective of this pilot research was (1) compare active previous measurements leptin anthropometrics; (2) assess consistency across time in population; (3) extend our understanding potential population variation ghrelin. Two serum samples separated 10 days at same...
Abstract Objectives Voxelotor can increase hemoglobin levels in patients living with sickle cell disease (SCD). A clinician who is monitoring voxelotor response may want to know whole-blood concentration, but this cannot be measured most clinical settings. However, has been demonstrated cause “peak splitting” common methods of measurement such as capillary zone electrophoresis (CZE) and high-performance liquid chromatography (HPLC). We hypothesized that we could use the size peak split...