- Hematopoietic Stem Cell Transplantation
- Acute Lymphoblastic Leukemia research
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Neuroendocrine Tumor Research Advances
- IgG4-Related and Inflammatory Diseases
- Acute Myeloid Leukemia Research
- RNA Interference and Gene Delivery
- Immunotherapy and Immune Responses
- Fungal Infections and Studies
- Radiopharmaceutical Chemistry and Applications
- Renal and related cancers
- Alkaline Phosphatase Research Studies
- Antifungal resistance and susceptibility
- Chronic Myeloid Leukemia Treatments
- Rheumatoid Arthritis Research and Therapies
- Vascular Tumors and Angiosarcomas
- Cytokine Signaling Pathways and Interactions
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- S100 Proteins and Annexins
- Urticaria and Related Conditions
- Eosinophilic Disorders and Syndromes
- RNA modifications and cancer
- Spondyloarthritis Studies and Treatments
- Otitis Media and Relapsing Polychondritis
Shandong University
2025
Peking University People's Hospital
2008-2024
Peking University
2010-2024
To investigate the rheumatic antibodies on characteristics of neuromyelitis optic spectrum disorders. All patients were tested for AQP4-IgG. There three groups, AQP4+NMOSD, AQP4-NMOSD and control group. MRI was performed. Clinical characteristics, including sex, age, disease duration, number type relapse, autoantibodies, MRI, OCT results scores obtained from EDSS at time attack remission prospectively recorded. Patients controls underwent peripapillary RNFL macular volume scanning. In AQP4+...
Objective Serum soluble CD25 (sCD25) could be used as a biomarker for disease activity in conditions associated with T-cell activation including various autoimmune diseases. This study aimed to explore the role of sCD25 an indicator and organ involvement patients systemic lupus erythematosus (SLE). Methods samples were collected from 107 SLE 92 age-matched healthy controls (HCs). All followed up 24 weeks, was measured by enzyme-linked immunosorbent assay. Clinical laboratory data recorded at...
Abstract Introduction SIL ‐ TAL 1 rearrangement is common in T‐cell acute lymphoblastic leukemia (T‐ ALL ). However, whether this fusion gene might be used as a reliable marker of minimal residual disease ( MRD ) following allogeneic stem cell transplantation (allo‐ HSCT remains unknown Methods The clinical data consecutive 29 patients with T‐ who received allo‐ were collected. Their evaluated by 1, Wilms' tumor WT expression, and the leukemia‐associated immunophenotype LAIP . Results median...
Objective To assess the diagnostic value of salivary gland ultrasonography (SGUS) for IgG4-related sialadenitis. Methods Ultrasonography examination major glands was conducted 48 sialadenitis patients and 50 Sjogren's syndrome patients, whose ages disease duration were matched. The imaging features graded using two different scoring systems (0-16 0-48, respectively) obtained from grades bilateral parotid submandibular glands. scores used to further evaluate in compare them with patients....
Angioimmunoblastic T-cell lymphoma is a rare lymphoma. The clinical manifestations are not specific. In addition to the common of lymphomas such as fever, weight loss, night sweats and lymphadenopathy, it may also have skin rashes, arthritis, multiple serous effusions, eosinophilia other systemic inflammatory or immune symptoms. cells angioimmunoblastic originates from follicular helper T cells, structure lymph nodes disappears. tumor microenvironment, in there large number over-activated...
1Peking University People's Hospital, 2Peking 3Peking 4Peking 5Peking 6Peking Hospital
<h3>Background</h3> <sup>99</sup>Tc-MDP has been used in Chinese RA patients for over 15 years and many more studies have focused on this agent RA. However, the previous limited its effect effects of anti-inflammation. As a special form bisphosphonate, anti-osteoporotic is unclear. <h3>Objectives</h3> To systematically investigate technetium-99 conjugated with methylene diphosphonate (<sup>99</sup>Tc-MDP), an anti-inflammatory drug effective treating rheumatoid arthritis (RA), cortical...
Rheumatoid arthritis (RA) is a heterogeneous autoimmune disease whose etiopathogenesis largely unknown. Available treatments, though effective, are insufficient in so far as there no cure for major proportion of patients. In those patients the becomes chronic with progressive joint damage, disability, and limitation participation. Current treatment approaches include pain-relieving drugs anti-inflammatory medications that slow combined physical therapies involving well-balanced, highly...
Abstract Introduction To determine the presence of respiratory impairment in community-living subjects with a history poliomyelitis. Methods In study conducted from July 2013-January 2014, we used national database to recruit individuals (212 males, 86 females) north and south provinces China known prior poliomyelitis infection &gt;25 years previously. 298 (96.8%) completed overnight oximetry collect number/hr drops oxygen saturation &gt;4% (ODI4) Epworth Sleepiness Scale (ESS); many...