- Cerebral Venous Sinus Thrombosis
- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Vascular Malformations Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Moyamoya disease diagnosis and treatment
- Cerebrovascular and Carotid Artery Diseases
- MicroRNA in disease regulation
- Neurological Complications and Syndromes
- Extracellular vesicles in disease
- Blood Coagulation and Thrombosis Mechanisms
- Neurological Disease Mechanisms and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Ischemia and Reperfusion
- Neuroinflammation and Neurodegeneration Mechanisms
- Pituitary Gland Disorders and Treatments
- Radioactive contamination and transfer
- Stroke Rehabilitation and Recovery
- Radioactivity and Radon Measurements
- Circular RNAs in diseases
- Groundwater and Isotope Geochemistry
- Genetic Associations and Epidemiology
- Leptospirosis research and findings
- Intracranial Aneurysms: Treatment and Complications
- Lipid metabolism and disorders
Chinese Institute for Brain Research
2017-2025
Capital Medical University
2017-2025
Tianjin University of Science and Technology
2024
Ministry of Natural Resources
2023-2024
Xuan Wu Hospital of the Capital Medical University
2022-2024
Nanjing University of Chinese Medicine
2023
Wuxi Fourth People's Hospital
2023
Ministry of Natural Resources
2023
Henan Polytechnic University
2023
Shanghai Ocean University
2023
Despite decades of formidable exploration, multi-organ ischemia-reperfusion injury (IRI) encountered, particularly amongst elderly patients with clinical scenarios, such as age-related arteriosclerotic vascular disease, heart surgery and organ transplantation, is still an unsettled conundrum that besets clinicians.Remote ischemic conditioning (RIC), delivered via transient, repetitive noninvasive IR interventions to distant organs or tissues, regarded innovative approach against IRI.Based on...
Background and purpose Idiopathic intracranial hypertension ( IIH ) is characterized by abnormally elevated pressure ICP without identifiable etiology. Recently, however, a subset of patients with presumed have been found isolated internal jugular vein IJV stenosis in the absence abnormalities. Methods Fifteen consecutive were screened from 46 suspected as finally confirmed stenosis. The stenotic was corrected stenting when trans‐stenotic mean gradient (∆ MPG equal to or higher than 5.44 cmH...
Abstract Recently, internal jugular vein stenosis (IJVS) is gaining increasing attention from clinical researchers due to a series of confounding symptoms that impair the quality life in affected individuals but cannot be explained by other well-established causes. In this study, we aimed elucidate features, neuroimaging characteristics and pathogenesis IJVS, explore their possible correlations, attempt provide useful clues for diagnosis treatment. Forty-three eligible patients with...
Abstract Aims This study aimed to identify the clinical profiles of cervical spondylosis‐related internal jugular vein stenosis (IJVS) comprehensively. Methods A total 46 patients, who were diagnosed as IJVS induced by spondylotic compression recruited. The manifestations and imaging features presented particularly in this study. Results Vascular was present 69 out 92 veins, which, 50.7% (35/69) stenotic vessels compressed transverse process C1, 44.9% (31/69) C1 combined with styloid...
Distinguishing moyamoya disease (MMD) from intracranial atherosclerotic stenosis (IAS) is critical for its treatment and outcome evaluation. This study aimed to use the combined sequences of high-resolution magnetic resonance imaging (HRMRI) arterial spin labeling MR (ASL-MR) identify two entities accurately.This prospective enrolled 58 patients with middle cerebral artery (MCA) steno-occlusion identified by digital subtraction angiography (DSA), including 27 cases MMD 31 IAS. All underwent...
Our previous study revealed that remote ischemic conditioning (RIC) reduced the incidence of stroke or TIA in octo- and nonagenarians with intracranial atherosclerotic stenosis (ICAS). Herein, we aimed to investigate whether RIC would influence progression white matter hyperintensities (WMHs) cognitive impairment same group patients. Fifty-eight patients ICAS were randomly assigned a 1:1 ratio receive standard medical treatment (n=30) versus sham-RIC (n=28). The protocol consisted 5 cycles...
We aimed to evaluate the safety and effectiveness of short-term remote ischemic postconditioning (RIPC) in acute stroke monkey models.Acute monkeys were allocated four groups based on number limbs exposed RIPC. RIPC was initiated by 5-min cuff inflation/deflation cycles target limb(s) for 5-10 bouts. Vital signs, skin integrity, brain MRI, serum levels cardiac enzymes (myoglobin, creatine kinase [CK], CK-muscle/brain [CK-MB]), one inflammatory marker (high-sensitivity C-reactive protein...
<b><i>Objective:</i></b> Parkinson’s disease (PD) is a profoundly incapacitating neurodegenerative disorder, which presents substantial challenge to the economic sustainability of global healthcare system. The present study seeks clarify factors that contribute costs associated with PD hospitalization and analyze burden it imposes. <b><i>Methods:</i></b> We examined data 19,719 patients primary diagnosis who were admitted hospitals in Hubei...