- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Aortic aneurysm repair treatments
- Coronary Interventions and Diagnostics
- Mechanical Circulatory Support Devices
- Cardiac tumors and thrombi
- Atrial Fibrillation Management and Outcomes
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Surgical site infection prevention
- Anesthesia and Neurotoxicity Research
- Cardiac pacing and defibrillation studies
- Cardiac Ischemia and Reperfusion
- Anesthesia and Sedative Agents
- Cardiac Arrhythmias and Treatments
- Orthopedic Infections and Treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Congenital Heart Disease Studies
- Cardiac electrophysiology and arrhythmias
- Infectious Aortic and Vascular Conditions
- Surgical Simulation and Training
University Hospital of Basel
2016-2025
University of Basel
2012-2025
Hospital Base
2022-2023
Triemli Hospital
2007-2013
University of Zurich
2002-2008
University Hospital of Zurich
1985-2007
Herzgefäss Medizin Klinik Im Park
2003-2005
Kerckhoff Klinik
1996-2000
Deutsches Herzzentrum München
2000
Max Planck Society
1997-1999
Background In view of the rising global burden severe symptomatic aortic stenosis, its early recognition and treatment is key. Although patients with classical low-flow, low-gradient (C-LFLG) stenosis have higher rates death after transcatheter valve implantation (TAVI) when compared high-gradient (HG) there conflicting evidence on rate in paradoxical (P-LFLG) stenosis. Therefore, we aimed to compare outcomes real-world HG, C-LFLG, P-LFLG undergoing TAVI. Methods Results Clinical up 5 years...
Objective: Arterial perfusion through the right subclavian artery is proposed to avoid intraoperative malperfusion during repair of acute type A dissection. This study evaluated clinical and neurological outcome patients undergoing surgery aortic dissection following arterial cannulation compared femoral approach. Methods: From 1/97 1/03, 122 consecutive underwent for Subclavian was performed in 62 versus 60 patients. Clinical characteristics both groups were similar. Mean age 61 years...
Aims: To evaluate short-term clinical outcomes following transcatheter aortic valve implantation (TAVI) using CE-mark approved devices in Switzerland. Methods and results:The Swiss TAVI registry is a national, prospective, multicentre, monitored cohort study evaluating consecutive patients undergoing at cardiovascular centres Switzerland.From February 2011 to March 2013, total of 697 underwent for native stenosis (98.1%), degenerative bioprosthesis (1.6%) or severe regurgitation...
Background/Objectives: The present study introduces our targeted approach for concomitant surgical ablation (CSA) using non-invasive phase mapping (NIPM) and describes its effectiveness regarding freedom from atrial fibrillation (AF). Methods: This retrospective included cardiac patients undergoing preoperative NIPM CSA guidance. primary outcome was AF six months after surgery. Key secondary outcomes were at hospital discharge three months, frequency of biatrial ablation, feasibility safety,...
Background Although patient-reported outcome measures (PROMs) as an integral part of value-based healthcare have important potential for clinical issues, e.g., shared decision-making, data are limited. Thus, the aim this study was to report initial results when introducing PROMs in setting cardiac surgery. Methods Patients undergoing elective coronary artery bypass grafting (CABG) were included. Three questionnaires (Seattle Angina Questionnaire 7 [SAQ-7], Rose Dyspnea Scale [RDS], and...
Summary: Breast augmentation is a popular cosmetic procedure that generally considered safe. However, the rising trend of nonspecialists performing these procedures has increased risk complications, including rare but serious acute bleeding. We present case healthy 22-year-old patient who experienced bleeding after bilateral breast by nonplastic surgeon, resulting in massive hypovolemic shock required 27 packed red blood cell (PRBC) transfusions and led to cardiopulmonary failure. The had 2...
OBJECTIVE To assess the clinical implementation and report preliminary results of a novel technique called Ozaki procedure for stentless aortic valve replacement through reconstruction leaflets from autologous pericardium. METHOD Between September 2015 May 2017 30 patients (20 males, mean ± standard deviation age 66.83 10.55 years) suffering stenosis (AS, n = 7), regurgitation (AR, 12), or combination both (AS/AR, 11) were assigned an procedure. The glutaraldehyde-treated pericardium was...
Wire closure still remains the preferred technique despite reasonable disadvantages. Associated complications, such as infection and sternal instability, cause time- cost-consuming therapies. We present a new tool for with its first clinical experience results. The ZipFixTM System is based on cable-tie principle. It primarily consists of biocompatible Poly-Ether-Ether-Ketone implants predominantly used peristernally through intercostal space. system provides large implant-to-bone contact...
This study compares the influence of two different annuloplasty attachment suture applications, namely use an automated fastener versus manually tied knots using a traditional knot pusher, on total operation time, cardiopulmonary-bypass time and cross-clamp short-term outcome. Sixty patients underwent isolated minimally invasive mitral valve repair in Carpentier Type-II disease with implantation ring combination correction prolapsing leaflet artificial chords. The first 30 after...
Background: Aim of this study was to evaluate the outcomes endocarditis patients undergoing valve surgery with Cytosorb® hemoadsorption (HA) device during cardiopulmonary bypass. Methods: From 2009 until 2019, 241 had undergone due at Department Cardiac Surgery, University Hospital Basel. We compared who received HA (n = 41) versus without 200), after applying inverse probability treatment weighting. Results: In-hospital mortality, major adverse cardiac and cerebrovascular events...
Background: The saphenous vein is an established conduit for coronary revascularization. Disadvantages of traditional harvest technique are significant pain and morbidity. We compared the endoscopic with method. Method: 140 artery bypass graft (CABG) patients were randomized into 2 groups: harvesting (EVH; n = 80) open (OVH; 60). Analysis included preoperative risk factors wound complication, time, injury, intraoperative postoperative complications. Patient follow-up lasted 3 months....
Blood pumps are routinely used for circulatory and pulmonary support. However, blood trauma pump failure remain severe drawbacks of currently available models. This study evaluated the first clinical application a new, totally bearingless centrifugal (CentriMag).A consisting an electromagnetic suspended impeller was as during beating-heart coronary artery bypass grafting in 11 patients (mean weight, 77.4 kg). Heparin bolus 150 IU/kg body weight administered, activated clotting time...
Coronary artery bypass graft surgery (CABG) remains the method of choice for patients with left main disease (LMD). The precise role off-pump coronary (OPCABG) unclear in this setting. We report safety and feasibility a routine OPCABG approach to LMD.From 2002 2007, 983 underwent myocardial revascularization at our institution. compared 343 LMD (group A) 640 without B). relationship between presence outcome procedures was statistically assessed. A composite endpoint (30-day mortality,...
OBJECTIVES:To determine the difference in sternal infection and other infectious events between conventional wire cable-tie-based closure techniques post-sternotomy a collective of patients after cardiac surgery. METHODS:The ZipFix™ (ZF) system consists biocompatible poly-ether-ether-ketone (PEEK) cable-tie that surrounds sternum through intercostal space provides large implant-to-bone contact.Between 1 February 2011 31 January 2012, 680 operations were performed via sternotomy at our...