Jesús Sepúlveda-Delgado

ORCID: 0000-0003-1393-653X
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About
Contact & Profiles
Research Areas
  • Mosquito-borne diseases and control
  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Vectors
  • Malaria Research and Control
  • Systemic Sclerosis and Related Diseases
  • T-cell and B-cell Immunology
  • Monoclonal and Polyclonal Antibodies Research
  • Systemic Lupus Erythematosus Research
  • COVID-19 Clinical Research Studies
  • Vasculitis and related conditions
  • Vaccine Coverage and Hesitancy
  • Dermatologic Treatments and Research
  • Connective Tissue Growth Factor Research
  • Atherosclerosis and Cardiovascular Diseases
  • Autoimmune and Inflammatory Disorders Research
  • Primary Care and Health Outcomes
  • SARS-CoV-2 detection and testing
  • Healthcare Systems and Reforms
  • Liver Disease Diagnosis and Treatment
  • Immune responses and vaccinations
  • Eosinophilic Disorders and Syndromes
  • Infectious Encephalopathies and Encephalitis
  • Inflammatory Myopathies and Dermatomyositis
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Immunodeficiency and Autoimmune Disorders

Hospitales Regionales de Alta Especialidad
2016-2025

Hospital General De Zona
2018-2022

Mexican Social Security Institute
2014-2021

Universidad Nacional Autónoma de México
2014-2019

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2018

Universidad del Tacana
2018

Hospital de Especialidades
2017-2018

Centro Médico Nacional La Raza
2017-2018

Abstract Background InVITE (NCT# 05096091) is a 7-country observational study assessing immune responses to COVID-19 vaccines offered from national vaccination programs. This analysis focuses on the response 2 months after receipt of booster vaccine (third dose) among participants Mexico and Mongolia. Vaccines assessed were mRNA (Comirnaty, Pfizer (BioNTech), non-replicating viral vector (Vaxzevria, Oxford/AstraZeneca; Sputnik-V, Gam-COVID-Vac), or inactivated virus (CoronaVac, SinoVac...

10.1093/ofid/ofae631.2213 article EN cc-by Open Forum Infectious Diseases 2025-01-29

The emerging chikungunya virus (CHIKV), is an arbovirus causing intense outbreaks in North America. situation Mexico alarming, and CHIKV threatens to spread further throughout Clinical biological features of CHIKF have not been well described; thus, we conducted a cross sectional study outbreak Chiapas, Southern characterize these features.We collected blood samples from patients suspected having fever (CHIKF) who presented Hospital ISSSTE Dr. Roberto Nettel Tapachula, Mexico. In addition...

10.1371/journal.pone.0186923 article EN cc-by PLoS ONE 2017-10-24

BackgroundPoint-of-care rapid tests to identify SARS-CoV-2 can have clinical benefits.MethodsA cross-sectional study in adults visiting emergency services or screening sites of referral hospitals for COVID-19 validate the diagnostic performance a antigen test (Abbott's Panbio) compared with reverse transcription-polymerase chain reaction (RT-PCR) testing. Tests were performed by health personnel routine situation during outbreak.ResultsA total 1060 participants (mean age 47, 46%...

10.1016/j.ijid.2021.10.027 article EN cc-by-nc-nd International Journal of Infectious Diseases 2021-10-22

Liver cancer is the fourth leading cause of cancer-related death worldwide. In Mexico, there a high burden liver mortality in rural states, which affects both women and men equally. Thus, we aimed to describe demographic clinical characteristics hepatocellular (HCC) by sex Mexico. Demographic information were extracted retrospectively from medical records patients with HCC initially treated (2015-2022) at participating institutions national survey across country. The male-to-female ratio was...

10.20944/preprints202405.1998.v1 preprint EN 2024-05-30

Phase III clinical trials have documented the efficacy of SARS-CoV-2 vaccines in preventing symptomatic COVID-19. Nonetheless, it is imperative to continue analyzing response different real-life studies. Our objective was evaluate effectiveness five hospitalized patients with COVID-19 during third outbreak Mexico dominated by Delta variant.A test-negative case-control study performed nine tertiary-care hospitals for We estimated odds ratios (OR) adjusted variables related a priori likelihood...

10.3390/vaccines11121779 article EN cc-by Vaccines 2023-11-28

Zika has been associated with a variety of severe neurologic manifestations including meningitis and encephalitis. We hypothesized that it may also cause mild to subclinical neurocognitive alterations during acute infection or over the long term. In this observational cohort study, we explored whether alterations, estimate its frequency duration, compare other illnesses in people suspected infection, region Tapachula Chiapas, Mexico 2016–2018. enrolled patients who were at least 12 years old...

10.3389/fneur.2021.631801 article EN cc-by Frontiers in Neurology 2021-03-22

ABSTRACT BACKGROUND Point-of-care rapid tests to identify SARS-CoV-2 can be of great help because, in principle, they allow decisions made at the site care for treatment, or separation cohorts avoiding cross-infection, especially emergency situations. METHODS A cross sectional study adults requesting Emergency Rooms (ER), outpatient clinics referral hospitals COVID-19, define diagnostic characteristics a antigen test (the Abbott Panbio™) having as gold standard RT-PCR SARS-CoV-2. Health...

10.1101/2021.05.24.21257020 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2021-05-24

Systemic lupus erythematosus (SLE) is a clinically and genetically heterogeneous disease particularly prevalent in Mexico. Althoughits etiology unknown, genetic factors strongly influence its presenceas well as triggering factors, such viral infections, including Cytomegalovirus Epstein-Barr virus. Here,the study presents the appearance of de novoSLE (patients who did not present SLE before virus infection, corroborated by serological analysis negative for antinuclear antibodies) cases...

10.46701/apjbg.2018042018127 article EN Blood and Genomics 2018-01-01

Liver cancer is the fourth leading cause of cancer-related death worldwide. In Mexico, there a high burden liver mortality in rural states, affecting both women and men equally. Thus, we aimed to describe demographic clinical characteristics hepatocellular (HCC) by sex Mexico. Demographic information was extracted retrospectively from medical records patients with HCC initially treated (2015-2022) at institutions participating national survey across country. The male-to-female ratio...

10.3390/diseases12100262 article EN cc-by Diseases 2024-10-21

The introduction of Zika and chikungunya to dengue hyperendemic regions increased interest in better understanding characteristics these infections. We conducted a cohort study Mexico evaluate the natural history infection. describe here frequency Zika, virus infections immediately after Mexico, baseline participants for each type infection.Prospective, observational evaluating infection Mexico-Guatemala border area. Patients with fever, rash or both, meeting modified criteria PAHO probable...

10.1186/s12879-021-06520-x article EN cc-by BMC Infectious Diseases 2021-08-28

<h3>Background</h3> Granulomatosis with polyangiitis (GPA) has been transformed from life-threatening conditions to chronic relapsing long-term diseases as a result of significant advances in immunosuppressive therapy. Structured clinical assessment using Vasculitis Damage Index (DVI) should form the basis treatment plan and be used document progress. <h3>Objectives</h3> To investigate manifestations localized systemic granulomatosis poliangiitis Mexican patients <h3>Methods</h3> We enrolled...

10.1136/annrheumdis-2017-eular.5690 article EN Annals of the Rheumatic Diseases 2017-06-01
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