A5039365591- T-cell and B-cell Immunology
- Immune Cell Function and Interaction
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Aortic aneurysm repair treatments
- Monoclonal and Polyclonal Antibodies Research
- Atherosclerosis and Cardiovascular Diseases
- Systemic Lupus Erythematosus Research
- Infectious Aortic and Vascular Conditions
- Glycosylation and Glycoproteins Research
- Retinal Diseases and Treatments
- Moyamoya disease diagnosis and treatment
- NF-κB Signaling Pathways
- Rheumatoid Arthritis Research and Therapies
- Immunotherapy and Immune Responses
- Vaccine Coverage and Hesitancy
- Immune Response and Inflammation
- Connective tissue disorders research
- Cutaneous Melanoma Detection and Management
- Neurological Complications and Syndromes
- Immunodeficiency and Autoimmune Disorders
- COVID-19 and Mental Health
- Traditional and Medicinal Uses of Annonaceae
- Glaucoma and retinal disorders
- vaccines and immunoinformatics approaches
University of El Salvador
2022-2025
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2019-2022
Secretaria de Salud
2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current disease 2019 (COVID-19) pandemic, affecting more than 219 countries and causing death of 5 million people worldwide. The genetic background represents a factor that predisposes way host responds to SARS-CoV-2 infection. In this sense, variants ACE ACE2 could explain observed interindividual variability COVID-19 outcomes. order improve understanding how are involved in severity COVID-19, we included...
Multiple factors are implicated in the etiology and pathogenesis of Abdominal Aortic Aneurysms (AAA). Available literature genetic studies has previously suggested possible roles autoimmunity, predisposition ethnic susceptibility. Due to association with autoimmune diseases proven application population genetics, we aimed investigate alleles Class II Human Leukocyte Antigens (HLA-DRB1) Mexican Mestizo aortic aneurysms determine associations susceptibility.We performed a case Control Study;...
Autoimmune thyroid disease (AITD) is the most common autoimmune disorder worldwide. Remarkably, it commonly accompanied by other diseases, such as rheumatoid arthritis (RA). The immunopathogenic mechanisms behind coexistence of these disorders are still not completely understood. Immunogenetics influences physiopathology diseases since ethnicity plays an essential role in inheritance susceptibility markers. High-resolution HLA class II typing was performed using a sequence-based method....
Systemic Lupus Erythematosus (SLE) is an autoimmune inflammatory disorder for which Major Histocompatibility Complex (MHC) genes are well identified as risk factors. SLE patients present different clinical phenotypes, partly explained by admixture patterns variation among Mexicans. Population genetic has insight into the high variability of Mexicans, mainly described through HLA gene studies with anthropological and biomedical importance. A prospective, case-control study was performed. In...
En la lucha por protección del medio ambiente y salud de población, es vital importancia encontrar formas alternativas control para el combate insectos vectores como Aedes aegypti. Una fuente ello lo constituyen las plantas que posean principios activos potentes con alta estabilidad química acción insecticida. este estudio se determinó actividad larvicida los extractos etanólicos acuosos semilla Annona diversifolia, hojas tallos deYucca guatemalensis raíz Petiveria alliacea sobre larvas...
Background Melanoma is an aggressive cutaneous cancer. Acral lentiginous melanoma a subtype arising on palms, soles, and nail-units. The incidence, prevalence prognosis differ among populations. link between expression of major histocompatibility complex Class II alleles progression known. However, available studies report variable results regarding the association with specific HLA loci. Aims aim study was to determine allele frequencies in acral patients healthy Mexican Mestizo...
Moyamoya Disease (MD) is an occlusive cerebral vasculopathy that rarely reported in the pediatric population and associated with Cerebrovascular Accidents (CVA).We herein present a case multiple comorbidities MD; imaging studies confirmed ischemia arteriovenous malformations.The diagnoses of MD, trisomy 21, Antiphospholipid Syndrome (APS) were confirmed, patient was treated thrombo-prophylaxis, antithrombotic immunomodulation treatment; on follow-up, remains asymptomatic.The prompt diagnosis...
Introduction: Glaucoma is a prevalent disease seen in the Ophthalmology department that includes group of neurodegenerative eye pathologies associated with total loss vision. It known for its clinical diversity and secondary to this, it assumed multiple genes play role pathogenesis. Among these, those regulate immune response which HLA are particular interest because they have been subgroup glaucoma patients as Primary Open Glaucoma. Methods: In this study, we studied 3 different groups whom...