A5074432967- Neonatal Respiratory Health Research
- COVID-19 Impact on Reproduction
- Neonatal and fetal brain pathology
- Global Maternal and Child Health
- Congenital Diaphragmatic Hernia Studies
- COVID-19 Clinical Research Studies
- Retinopathy of Prematurity Studies
- SARS-CoV-2 and COVID-19 Research
- Blood groups and transfusion
- Maternal and Neonatal Healthcare
- Blood disorders and treatments
- Cardiac Arrest and Resuscitation
- Thyroid Disorders and Treatments
- Infant Development and Preterm Care
- Ethics in medical practice
- Erythrocyte Function and Pathophysiology
- Spinal Dysraphism and Malformations
- Vaccine Coverage and Hesitancy
- Pregnancy and preeclampsia studies
- Child and Adolescent Health
- Cerebrospinal fluid and hydrocephalus
- Trauma Management and Diagnosis
- Neonatal and Maternal Infections
- HIV Research and Treatment
- Long-Term Effects of COVID-19
Instituto Nacional de Perinatología
2017-2024
University of Oxford
2024
Fundación Huésped
2014
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the current disease 2019 (COVID-19) pandemic, affecting more than 219 countries and causing death of 5 million people worldwide. The genetic background represents a factor that predisposes way host responds to SARS-CoV-2 infection. In this sense, variants ACE ACE2 could explain observed interindividual variability COVID-19 outcomes. order improve understanding how are involved in severity COVID-19, we included...
The perinatal consequences of SARS-CoV-2 infection are still largely unknown. This study aimed to describe the features and outcomes pregnant women with or without after universal screening was established in a large tertiary care center admitting only obstetric related conditions severe COVID-19 Mexico City. retrospective case-control integrates data between April 22 May 25, 2020, during active community transmission Mexico, one highest test positivity percentages worldwide. Only neonates...
Introduction Severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) infection triggers inflammatory clinical stages that affect the outcome of patients with coronavirus disease 2019 (COVID-19). Disease severity may be associated a metabolic imbalance related to amino acids, lipids, and energy-generating pathways. The aim this study was characterize profile acids acylcarnitines in COVID-19 patients. A multicenter, cross-sectional carried out. total 453 individuals were classified by...
(1) This study aimed to evaluate characteristics, perinatal outcomes, and placental pathology of pregnant women with or without SARS-CoV-2 infection in the context maternal PCR cycle threshold (CT) values. (2) was a retrospective case-control third-level health center Mexico City universal screening by RT-qPCR. The association COVID-19 manifestations, preeclampsia, preterm birth variables CT values were assessed logistic regression models decision trees. (3) Accordingly, 828 298 had negative...
Passive transplacental immunity is crucial for neonatal protection from infections. Data on the correlation between to SARS-CoV-2 and adverse outcomes scarce. This work aimed describe seropositivity in context of maternal infection, seropositivity, outcomes. retrospective nested case-control study enrolled high-risk pregnant women with a RT-PCR positive test who gave birth at Instituto Nacional de Perinatología Mexico City their term neonates. Anti-SARS-CoV-2 IgG antibodies cord blood...
Over the last 20 years, incidence of vertical HIV transmission has decreased from 25%–42% to less than 1%. Although there are no signs infection, health HIV-exposed uninfected (HEU) infants is notoriously affected during first months life, with opportunistic infections being most common disease. Some studies have reported effects on transfer antibodies, but little known about subclass distribution these antibodies. We proposed evaluate total IgG concentration and its subclasses in HIV+...
La hemorragia peri-intraventricular (HIV) es la complicación neurológica más importante de prematurez, con alteraciones en el neurodesarrollo a largo plazo. El objetivo del trabajo fue describir los factores riesgo asociados HIV neonatos < 1500 g al nacer que ingresaron UCIN. Se realizó un estudio cohorte prematuros ingresados UCIN 2016, seguimiento hasta su egreso, domicilio o por defunción. analizaron variables perinatales y neonatales. Para análisis estadístico se comparó desarrollaron no...
To develop quality of care (QoC) indicators, evaluate the processes (QPC) and clinical outcomes, analyze association between QPC severe outcomes preterm newborns admitted to neonatal intensive units (NICUs).Mixed methods approach: (1) development QoC indicators via modified RAND/UCLA method; (2) cross-sectional study evaluation (3) multiple logistic regression analysis ascertain outcomes.Two NICUs belonged Mexican Institute Social Security in Mexico City.About 489 neonates (<37 weeks...
En los últimos años la incidencia de hipotiroidismo congénito se ha incrementado casi al doble, lo cual atribuye mayor número nacimientos prematuros y embarazos múltiples, a cambios en el diseño programas tamizaje neonatal mejora las técnicas laboratorio disponibles, que han permitido detección formas sutiles enfermedad. Las estrategias varían acuerdo con objetivos cada programa últimas décadas generado controversia sobre: a) método ideal detección: tirotropina (TSH), tiroxina (T4) o toma...
Evaluating the ABO/RhD blood group and direct antiglobulin Coombs test (DAT) at birth is recommended good practice, but there variability in its universal implementation. This study aims to show comparative results various variables of clinical impact during hospital stay neonates with positive DAT compared those negative DAT, based on systematic detection birth.
Con los avances en la atención perinatal y neonatal, sobrevivencia de recién nacidos prematuros ha aumentado, el peso al nacer edad gestacional son determinantes más importantes mortalidad morbilidad neonatal. El objetivo del estudio fue determinar neonatos < 1,500 g egresados terapia intensiva neonatal una institución tercer nivel atención. Se realizó un análisis cohorte ingresados a terapia, consignando variables prenatales (uso esteroides prenatales, sulfato magnesio, vía resolución...
Los disrafismos espinales corresponden, dentro del Instituto Nacional de Perinatología «Isidro Espinosa los Reyes» la Ciudad México (INPer), a segunda causa atención neuroquirúrgica, después las hidrocefalias congénitas. El objetivo presente estudio es conocer características demográficas y epidemiológicas recién nacidos vivos, durante el último año, con defectos cierre tubo neural. Realizamos un descriptivo, observacional, retrospectivo, incluyendo todos vivos diagnóstico al egreso...
Retinopathy of prematurity (ROP) is the principal cause blindness during childhood. The objective this study was to analyze frequency ROP and risk factors associated with in a cohort very low birth weight infants.A cases controls (no ROP) infants less than 1500 g conducted. Perinatal neonatal variables were analyzed. For statistical analysis, χ2 test, Student's t-test Mann-Whitney's U-test used.For study, 282 neonates included: 152 (53.9%) 130 (46.1%) without ROP. most frequent stages...
Introducción: La retinopatía del prematuro (ROP) es una de las principales causas ceguera infantil.La inmadurez y la exposición a oxígeno son algunos factores riesgo.El objetivo este artículo fue analizar frecuencia los riesgo ROP en cohorte recién nacidos menores 1,500 g.Métodos: Se llevó cabo un estudio casos (con ROP) controles (sin g.Se analizaron variables prenatales neonatales, para su comparación se utilizaron pruebas estadísticas t Student, χ 2 U Mann-Whitney.Resultados: 282 nacidos:...
Los prematuros pueden presentar lesiones por reperfusión hiperóxica, lo que se deben evitar niveles nocivos de oxígeno. Determinar, durante la reanimación neonatal recién nacidos 27 a 30 semanas edad gestacional, los requerimientos oxígeno, el porcentaje saturación y su relación con morbilidad neonatal. Estudio transversal observacional analítico. Se incluyeron neonatos gestación; excluyeron malformaciones congénitas mayores las defunciones antes 36 gestacional corregida. dividieron en grupo...