A5025607512- Reproductive Physiology in Livestock
- Reproductive tract infections research
- Wildlife Ecology and Conservation
- Chromosomal and Genetic Variations
- Adolescent Sexual and Reproductive Health
- Glaucoma and retinal disorders
- Herpesvirus Infections and Treatments
- COVID-19 Clinical Research Studies
- Animal Virus Infections Studies
- Bird parasitology and diseases
- Rabies epidemiology and control
- Wnt/β-catenin signaling in development and cancer
- SARS-CoV-2 and COVID-19 Research
- Clostridium difficile and Clostridium perfringens research
- Viral gastroenteritis research and epidemiology
- Ecology and biodiversity studies
- CRISPR and Genetic Engineering
- SARS-CoV-2 detection and testing
- Plant Virus Research Studies
- Genital Health and Disease
- Corneal surgery and disorders
- Retinopathy of Prematurity Studies
- Primate Behavior and Ecology
- Urologic and reproductive health conditions
- Prostate Cancer Diagnosis and Treatment
University of Guelph
2022-2025
The University of Queensland
2017-2024
Health Sciences Centre
2023
Agriculture and Food
2019-2020
Abstract Since the emergence of SARS-CoV-2 in humans, novel variants have evolved to become dominant circulating lineages. These include D614G (B.1 lineage), Alpha (B.1.1.7), Gamma (P.1), Delta (B.1.617.2), and Omicron BA.1 (B.1.1.529) BA.2 (B.1.1.529.2) viruses. Here, we compared viral replication, pathogenesis, transmissibility these variants. Replication kinetics innate immune response against viruses were tested ex vivo human nasal epithelial cells (HNEC) induced pluripotent stem...
Chlamydiosis is the most documented and serious disease of koalas, characterized by ocular, urinary, reproductive lesions. Since little attention has been paid to pathological effects this infection in male system, we aimed determine incidence severity pathology associated with chlamydial koalas submitted koala hospitals southeast Queensland. The entire tract from 62 sexually mature not suitable for rehabilitation was evaluated 677 tissue samples were collected histology,...
Chlamydiosis is one of the main causes progressive decline koala populations in eastern Australia. While histologic, immunologic, and molecular studies have provided insights into basic function immune system, situ cell signatures during chlamydial infection reproductive tract koalas not been investigated. Thirty-two female 47 males presented to wildlife hospitals with clinical signs suggestive Chlamydia were euthanized entire collected for histology; immunohistochemistry (IHC) T-cell (CD3ε,...
The koala (Phascolarctos cinereus), while being an iconic Australian marsupial, has recently been listed as endangered. To establish improved understanding of normal reproductive anatomy, this paper brings together unpublished research which approached the topic from two perspectives: (1) establishment artificial insemination program, and (2) definition Chlamydia spp.-derived histopathological changes female urogenital system. Based on presentation histological processing over 70...
Transposons are ubiquitous mobile elements with the potential to trigger genome instability and mutations linked diseases 1,2 . Antisense piRNAs guide an adaptive immune system that silences established transposons during germline development 3 , but how responds new invaders is not understood. The KoRV retrovirus infects somatic cells sweeping through wild koala populations by a combination of horizontal vertical transfers, providing unique opportunity directly analyze response retroviral...
Abstract The prostate of the koala (Phascolarctos cinereus), and marsupials more generally, is primary contributor seminal fluid, yet comparatively little known about its microanatomy or biochemistry. This study explored evidence parenchymal segmentation prostate. three sexually mature koalas were processed for histopathology, histochemistry (Masson’s trichrome, Alcian Blue, periodic acid Schiff staining), immunohistochemistry using basal (tumor protein 63, cytokeratin 14) luminal...
Anti-sense piRNAs guide silencing of established transposons during germline development, and sense drive ping-pong amplification the antisense pool, but how responds to genome invasion is not understood. The KoRV-A gammaretrovirus infects soma sweeping through wild koalas by a combination horizontal vertical transfer, allowing direct analysis retroviral germline. Gammaretroviruses produce spliced Env mRNAs unspliced transcripts encoding Gag, Pol viral genome, we show that are almost...
To describe a case of congenital glaucoma in atiger (Panthera tigris).An 8-month-old intact female tiger wasreferred for suspected the right eye. The eye was buphthalmicwith moderate episcleral injection, circumferential superficial cornealneovascularization, corneal edema, and fixed dilated pupil. Tapetalreflection absent due to mature cataract. Rebound tonometry under generalanesthesia revealed 70 mmHg 21 left eye, respectively.A trans-conjunctival enucleation performedand globe submitted...