A5044157695- Pediatric Urology and Nephrology Studies
- Urological Disorders and Treatments
- Kidney Stones and Urolithiasis Treatments
- Urinary Bladder and Prostate Research
- Radiation Dose and Imaging
- Urinary and Genital Oncology Studies
- Colorectal Cancer Surgical Treatments
- Urinary Tract Infections Management
- Pelvic floor disorders treatments
- Sexual Differentiation and Disorders
- Congenital heart defects research
- Pediatric Pain Management Techniques
- Minimally Invasive Surgical Techniques
- Vagus Nerve Stimulation Research
- Bone and Joint Diseases
- Ultrasound and Hyperthermia Applications
- Testicular diseases and treatments
- Congenital gastrointestinal and neural anomalies
- Nerve injury and regeneration
- Escherichia coli research studies
- Urologic and reproductive health conditions
- Hernia repair and management
- Muscle and Compartmental Disorders
- Health, Environment, Cognitive Aging
- Ureteral procedures and complications
Children's National
2017-2023
Children's Hospital of Pittsburgh
2011-2016
Monroe Carell Jr. Children's Hospital
2016
Vanderbilt University Medical Center
2015-2016
Boston Children's Hospital
2015
University of Pittsburgh
2010-2014
University of Pittsburgh Medical Center
2010
Dartmouth College
2005-2006
Dartmouth Hospital
2005
University of Foggia
2002
Study results of single nucleotide polymorphisms (SNPs) and cancer susceptibility are often conflicting, possibly because the analytic challenges testing for multiple genetic environmental risk factors using traditional tools. We investigated relationship between DNA repair gene SNPs, smoking, bladder in 355 cases 559 controls enrolled a population-based study US. Our multifaceted analytical approach included logistic regression, multifactor dimensionality reduction, hierarchical interaction...
Abstract Adenocarcinoma of the exocrine pancreas is fourth leading cause cancer-related death in men and women U.S. Cytokines other proinflammatory mediators have been implicated inflammatory pancreatic diseases including pancreatitis cancer. We analyzed cytokine gene polymorphisms as risk factors for cancer using questionnaire data obtained by in-person interviews germ line DNA collected a population-based case-control study (532 cases 1,701 controls) conducted San Francisco Bay Area. used...
No AccessJournal of UrologyPediatric Urology1 Mar 2013Cost Analysis Pediatric Robot-Assisted and Laparoscopic Pyeloplasty Daniel P. Casella, Janelle A. Fox, Francis X. Schneck, Glenn M. Cannon, Michael C. Ost CasellaDaniel Casella , FoxJanelle Fox SchneckFrancis Schneck CannonGlenn Cannon OstMichael View All Author Informationhttps://doi.org/10.1016/j.juro.2012.08.259AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail...
The ability to de novo synthesize purines has been associated with the intracellular survival of multiple bacterial pathogens. Uropathogenic Escherichia coli (UPEC), predominant cause urinary tract infections, undergoes a transient lifestyle during which bacteria clonally expand into multicellular communities within cytoplasm bladder epithelial cells. Here, we characterized contribution conserved purine biosynthesis-associated locus cvpA-purF UPEC pathogenesis. Deletion cvpA-purF, or purF...
Posterior urethral valves occur in 1 : 5000 live births. Despite the high prevalence, few children that survive do poorly, with over 50% progressing to ESRD 10 years. The gold standard for post-natal diagnosis is voiding cystourethrography, while pre-natal dependent on routine screening ultrasonography. ability identify features of bladder outlet obstruction early fetal development, there no consensus how incorporate detection into current protocols. There has yet be a marker allows...
Urodynamic studies are crucial to neuropathic bladder management and they often determine surgical intervention. However, current evidence indicates that interpretations show poor agreement across physicians. We sought the interrater reliability of urodynamic interpretation in our practice. hypothesized there would be strong correlation among pediatric urologists similar training a single academic practice.We retrospectively identified patients with who underwent urodynamics at institution...
Sacral neuromodulation has been demonstrated to improve refractory bowel bladder dysfunction in children. The purpose of the current study was determine whether results are durable children after longer followup, with a lower body mass index at risk for device failure and pretreatment urodynamic evaluation can predict posttreatment outcome.Pediatric patients were enrolled following informed consent followed prospectively. All underwent preoperative videourodynamic 2-stage implantation...
Low intensity focused ultrasound has recently been identified as a novel method of stimulating targeted neurons. We hypothesized that stimulation the posterior tibial nerve would inhibit bladder contractions in an established rat model rhythmic contractions.Cyclical detrusor were initiated by placing transurethral catheter female rats and infusing saline into bladder. Transcutaneous pulses then delivered to lower extremity (overlying nerve) using single element spherically 250 kHz...
Akinetic mutism is a wakeful state of severe apathy and paucity volitional movement. Evidence indicates possible dopaminergic hypofunction within the anterior cingulate cortex. The authors present three cases acute onset akinetic successfully treated with intramuscular olanzapine.
Abstract Context Autosomal dominant and rarely de novo gain-of-function variants in the LHCGR gene are associated with precocious male puberty, while somatic have been found isolated Leydig cell adenomas hyperplasia. Bilateral diffuse tumor formation peripheral puberty has not reported. Case Description We present a boy gonadotropin-independent rapid virilization beginning infancy resistant to standard therapy. Treatment abiraterone addition letrozole bicalutamide proved effective. tumors...
Abstract Disclosure: S. Jumani: None. K. Shimy: D. Casella: J. Long: V. Gomez-Lobo: Introduction: Identifying gonads with ovarian and testicular components (ovotestis) can be difficult, despite multimodal imaging, biopsy, surgical visualization. Here, we describe an unexpected identification of ovotestis following the initiation tamoxifen in a patient 46XX Ovotesticular Difference Sexual Differentiation (DSD). Case: A 14YO affirmed male DSD presented to our clinic for management recurrent...
You have accessJournal of UrologyPediatrics: Testis, Varicocele & Stones1 Apr 2014MP26-12 RADIATION EXPOSURE IN PEDIATRIC PATIENTS UNDERGOING EVALUATION AND MANAGEMENT OF NEPHROLITHIASIS Benjamin Ristau, Daniel Casella, Omaya Banihani, Janelle Fox, Glenn Cannon, Francis Schneck, Steven Docimo, and Michael Ost RistauBenjamin Ristau More articles by this author , CasellaDaniel Casella BanihaniOmaya Banihani FoxJanelle Fox CannonGlenn Cannon SchneckFrancis Schneck DocimoSteven Docimo OstMichael...
Introduction: Spinal anesthesia has a long history as an effective and safe technique to avoid general in infants undergoing surgery. However, spinal was rarely used the primary anesthetic this population at our institution. This healthcare improvement initiative aimed increase percentage of successful placements circumcision, open orchidopexy, or hernia repair from 11% 50% by December 31, 2019, sustain that rate for 6 months. Methods: An interdisciplinary team created key driver diagram...