A5078838854- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions
- Hepatitis C virus research
- Cervical Cancer and HPV Research
- Liver Disease Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV, Drug Use, Sexual Risk
- COVID-19 Clinical Research Studies
- Viral Infections and Vectors
- Healthcare cost, quality, practices
- Tuberculosis Research and Epidemiology
- Innovations in Medical Education
- Travel-related health issues
- Vector-borne infectious diseases
- Genital Health and Disease
- Viral-associated cancers and disorders
- Animal Virus Infections Studies
- Insect and Pesticide Research
- Hepatitis B Virus Studies
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Use and Resistance
Tartu University Hospital
2020-2025
University of Tartu
2015-2021
University Hospital Cologne
2021
University of Tartu Natural History Museum and Botanical Garden
2020
Abstract Lyme disease is a tick-borne caused by bacteria of the genus Borrelia . The host factors that modulate susceptibility for have remained mostly unknown. Using epidemiological and genetic data from FinnGen Estonian Biobank, we identify two previously known variants an unknown common missense variant at gene encoding Secretoglobin family 1D member 2 ( SCGB1D2 ) protein increases disease. live burgdorferi (Bb) find recombinant reference inhibits growth Bb in vitro more efficiently than...
To define the status of infectious diseases (ID) as an approved specialty in Europe; to enumerate number specialists (in general and relation overall population) specialist trainees describe content, delivery evaluation postgraduate training ID different countries.Structured web-based questionnaire surveys March 2021 responsible national authorities, societies individual country representatives Section Infectious Diseases European Union for Medical Specialties. Descriptive analysis...
Objectives Estonia has one the highest number of new HIV diagnoses in European Union, mainly among injecting drug users and heterosexuals. Little is known incidence, which crucial for limiting epidemic. Using a recent infection testing algorithm (RITA) assay, we aimed to estimate incidence 2013. Methods All individuals aged ≥18 years newly‐diagnosed with January‐ December 2013, except blood donors those undergoing antenatal screening, were included. Demographic clinical data obtained from...
Background: Estonia is experiencing the new Eastern Europe human immunodeficiency virus (HIV) epidemic, with highest incidence of infections in EU. We describe demographic changes, HIV-related laboratory parameters and co-infections during concentrated HIV epidemic using Estonian Cohort Study (E-HIV) database, founded 2009. Methods: All 3750 subjects E-HIV database on December 31, 2013 were included. Subjects divided into risk groups: people who inject drugs (PWIDs), sexual transmission...
The World Health Organisation (WHO) calls for the elimination of cervical cancer (CC) as a public health issue. To achieve elimination, efforts must be aligned and accelerated. Women living with HIV (WLWH) have excess risk developing, dying from, CC over general population. Estimates screening programme coverage in Eastern European countries that experienced epidemics since early 2000's are scarce.
Background Serological assays to determine HIV incidence have contributed estimates of incidence, monitoring spread, and evaluation prevention strategies. Two frequently used are the Sedia HIV-1 LAg-Avidity EIA (LAg) Bio-Rad avidity (BRAI) with a mean duration recent infection (MDRI) 130 240 days for subtype B infections, respectively. Little is known about how these perform recombinant strains. We evaluated concordance in population infected mainly CRF06_cpx. Material/Methods Remnant serum...
In Eastern Europe, HIV-1 transmitted drug resistance (TDR) data, especially in the integrase (IN) region, are limited. Estonia, INSTI (integrase strand transfer inhibitors) TDR has been studied only prior to scale-up late 2010s. The current study aimed determine levels of protease (PR), reverse transcriptase (RT) and IN surveillance mutations (SDRMs) among newly diagnosed patients Estonia 2017. included 216 individuals from 1 January until 31 December 2017 Estonia. Demographic clinical data...
Despite the high number of SARS-CoV-2 infections, only a few cases dual infection have been reported. Here, we describe case COVID-19 caused simultaneously by Delta and Omicron variants in an immunocompetent individual during early emergence variant. A 73-year-old man was hospitalized with suspected acute coronary syndrome positive test result for RNA received routine testing at hospital. He experienced mild symptoms discharged on ninth day. We sequenced whole genome from sample obtained...
Abstract IntroductionThe World Health Organisation (WHO) calls fot the elimination of cervical cancer (CC) as a public health issue. To achieve elimination, efforts must be aligned and accelerated. Women living with HIV (WLWH) have excess risk for developing dying from CC over general population. Estimates screening (CCS) program coverage in Eastern European countries that experienced epidemics since early 2000s are scarce. MethodsThis population-based retrospective study uses healthcare...
Abstract Background Estonia has a typical Eastern European HIV epidemic where the most frequent co-infection is chronic hepatitis C (HCV). We aimed to describe changes in HCV prevalence, distribution of genotypes (GT), and treatment Estonian people living with over 15 years. Methods used data subjects included Cohort Study (E-HIV) before 31st December 2015. compared two time periods—first, 1st January 2000 2008 when was mostly spreading among who inject drugs (PWID) second, 2009 2015 started...
Reisimine muutub kogu maailmas uha populaarsemaks. Kuna reisimisel valisriikidesse on suurenenud risk puutuda kokku nakkushaigustega, konsulteerimine reisimeditsiini spetsialistiga olulisel kohal. Seda teevad aga vahem kui pooled voorriiki soitjatest. Artiklis antud ulevaade patsientide reisieelse noustamise olulisusest ja peamistest reisivaktsiinidest. Kasitletud A- B-viirushepatiiti, grippi, kohutuufust, marutobe, kollapalavikku, meningokokknakkust. Luhidalt peatutud ka tulevikusuundadel...
Abstract Background Estonia has a typical Eastern European HIV epidemic where the most frequent co-infection is chronic hepatitis C (HCV). We aimed to describe changes in HCV prevalence, distribution of genotypes (GT), and treatment Estonian people living with over 15 years. Methods used data subjects included Cohort Study (E-HIV) before 31 st December 2015. compared two time periods – first, 1 January 2000 - 2008 when was mostly spreading among who inject drugs (PWID) second, 2009 2015...