- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Maternal and fetal healthcare
- Pregnancy and preeclampsia studies
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiac Arrhythmias and Treatments
- Cardiac Imaging and Diagnostics
- Pulmonary Hypertension Research and Treatments
- Cardiomyopathy and Myosin Studies
- Acupuncture Treatment Research Studies
- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Physical Activity and Health
- Heart Failure Treatment and Management
- Atrial Fibrillation Management and Outcomes
- Hemodynamic Monitoring and Therapy
- Cardiac electrophysiology and arrhythmias
- Heart Rate Variability and Autonomic Control
- Traditional Chinese Medicine Studies
- Complementary and Alternative Medicine Studies
- COVID-19 Impact on Reproduction
- Cardiac Health and Mental Health
- Vascular Anomalies and Treatments
University of Illinois Chicago
2014-2025
University of Illinois Urbana-Champaign
2012-2025
University of Illinois System
2023
Vanderbilt University
2018-2020
University of Pittsburgh Medical Center
2015-2020
Pittsburg State University
2018
University of Pittsburgh
2016-2018
Baylor College of Medicine
2018
Washington University in St. Louis
2018
Collins College
2017
Peripartum cardiomyopathy (PPCM) is an idiopathic form of pregnancy-induced heart failure associated with preeclampsia. Circulating factors in late pregnancy are thought to contribute both diseases, suggesting a common underlying pathophysiological process. However, what drives this process remains unclear. Using serum proteomics, we identified the senescence-associated secretory phenotype (SASP), marker cellular senescence biological aging, as most highly up-regulated pathway young women...
OBJECTIVE: To describe the demographic characteristics of women in Illinois who died from cardiovascular disease during pregnancy or up until 1 year postpartum, addressing specific etiologies, timing death, proportion potentially preventable mortality, and factors associated with preventability. METHODS: This is a retrospective analysis Department Public Health Maternal Mortality Review process using International Classification Diseases, 9th Revision codes that attributed as immediate...
Background Heart failure (HF) is a leading cause of maternal morbidity and mortality in the United States, but prevalence, correlates, outcomes HF-related hospitalization during antepartum, delivery, postpartum periods remain unknown. The objective was to examine HF among pregnancy-related hospitalizations women 13 49 years age. Methods Results We used 2001 2011 Nationwide Inpatient Sample. Rates were calculated by patient hospital characteristics. Survey logistic regression estimate...
In peripartum cardiomyopathy, the prevalence of focal myocardial damage detected by late gadolinium enhancement (LGE) cardiovascular magnetic resonance is important to elucidate mechanisms injury and cardiac dysfunction. LGE equates irreversible injury, but in cardiomyopathy uncertain.Among 100 women enrolled within Investigations Pregnancy Associated Cardiomyopathy cohort, we recruited 40 at 13 centers undergo resonance, first weeks postpartum. Follow-up scans occurred 6 months postpartum,...
Cardiomyopathy (CM) and other cardiovascular conditions (OCVs) are among the most frequent causes of pregnancy-related death in United States.
Managing pregnancies in patients with prosthetic heart valves presents challenges including recurrent arrhythmia, bleeding, thrombosis, and infection. We present a woman valvular disease paroxysmal atrial arrhythmias who died after pregnancy examine how Maternal Mortality Review Committees address areas to improve maternal outcomes.
Approximately 53% of maternal mortality occurs in the postpartum period, a time with little monitoring and health surveillance. The objective this study was to test feasibility, usability, appropriateness, acceptability remote low-burden physiologic Black women, using novel soft wearable patch home vital sign for first 4 weeks postpartum. A prospective longitudinal cohort feasibility 20 women conducted equipment sensors measuring temperature, pulse oximetry, blood pressure, electrocardiogram...
Clinicians often fail to detect intraoperative ischemic electrocardiographic (ECG) changes when viewing oscilloscopes. Automated ST-segment monitors promise increase the detection of such ECG changes. We investigated capacity two commercially available myocardial ischemia in patients at high risk for developing during vascular and other noncardiac procedures. The were compared with reference monitors: (a) printed eight-lead ECGs, as interpreted by a cardiologist, (b) presence segmental wall...
There is limited data on electrocardiographic (ECG) abnormalities and their prognostic significance in women with peripartum cardiomyopathy (PPCM). We sought to characterize ECG findings PPCM explore the association of myocardial recovery clinical outcomes.We hypothesized that indicators remodeling would portend worse systolic function outcomes.Standard 12-lead ECGs were obtained at enrollment Investigations Pregnancy-Associated Cardiomyopathy study analyzed for 88 women. Left ventricular...
Purpose. As compared with minimal treatment (MT), to determine the effectiveness of a home-based walking intervention enhanced by behavioral strategies targeted and tailored African-American women (enhanced [ET]) on adherence, physical activity, fitness, body composition at 24 48 weeks. Design. Using quasi-experimental design, treatments were randomly assigned one two community health centers. Setting. The centers in predominately communities. Participants. Sedentary (156 ET, 125 MT) 40 65...
The etiology of peripartum cardiomyopathy remains unknown. One hypothesis is that an increase in the 16-kDa form prolactin pathogenic and suggests breastfeeding may worsen by increasing prolactin, while bromocriptine, which blocks release, be therapeutic. An autoimmune has also been proposed. authors investigated impact on cellular immunity myocardial recovery for women with IPAC (Investigations Pregnancy Associated Cardiomyopathy) study. Women who breastfed had elevated levels correlated...
Cardiac biomarkers are widely used in the nonpregnant population when acute cardiovascular (CV) pathology is suspected; however, behavior of these context pregnancy less well understood. Pregnant individuals often have symptoms that mimic those cardiac dysfunction, and complications may include CV disease. This paper will summarize our current knowledge on use provide suggestions how to tools clinical practice based available evidence. Natriuretic peptides troponin should not be measured...
The purposes of this study were to identify strategies successful in the recruitment African American (AA) women a home-based walking program and examine factors that contribute attrition, eligibility, ineligibility during screening protocol. Of 696 who contacted researchers, 281 (40.4%) enrolled study, 227 (32.6%) lost 188 (27%) ineligible. Those not due attrition or reported more family risk for cardiovascular disease (CVD) lived neighborhoods with higher poverty. Although our may have...
Skeletal muscle insulin resistance is a hallmark of Type 2 diabetes (T2DM) and may be exacerbated by protein modifications methylglyoxal (MG), known as dicarbonyl stress. The glyoxalase enzyme system composed 1/2 (GLO1/GLO2) the natural defense against stress, yet its expression, activity, regulation remain largely unexplored in skeletal muscle. Therefore, this study investigated stress subjects with T2DM (age: 56 ± 5 yr.; BMI: 32 kg/m ) compared lean healthy control (LHC; age: 27 1 22 )....