A5100660529- Land Use and Ecosystem Services
- Urban Heat Island Mitigation
- Remote Sensing and Land Use
- Species Distribution and Climate Change
- Ecology and Conservation Studies
- Ecology and Vegetation Dynamics Studies
- Hydrology and Watershed Management Studies
- Urban Green Space and Health
- Remote Sensing in Agriculture
- Cancer, Hypoxia, and Metabolism
- Hydrology and Drought Analysis
- Bacteriophages and microbial interactions
- Soil and Water Nutrient Dynamics
- Remote Sensing and LiDAR Applications
- Bacterial Genetics and Biotechnology
- Climate variability and models
- Plant Water Relations and Carbon Dynamics
- TGF-β signaling in diseases
- Forest Management and Policy
- Developmental Biology and Gene Regulation
- Clusterin in disease pathology
- Extracellular vesicles in disease
- Cephalopods and Marine Biology
- Identification and Quantification in Food
- Forest Insect Ecology and Management
St. Jude Children's Research Hospital
2025
Korea University
2019-2024
Pusan National University
2016-2024
Jeonbuk National University
2024
The Ohio State University
2022
Ewha Womans University
2022
Abstract Background Glioblastoma (GBM) is more difficult to treat than other intractable adult tumors. The main reason that GBM so it highly infiltrative. Migrasomes are newly discovered membrane structures observed in migrating cells. Thus, they can be generated from cells have the ability migrate along brain parenchyma. However, function of migrasomes has not yet been elucidated Results Here, we describe composition and with cell migration. Proteomic analysis revealed LC3B-positive...
Urban heat island (UHI) is a phenomenon that occurs in cities worldwide. Therefore, there an increasing need for studies on the changes UHI intensity and long-term trends based macroscopic characteristics related to urbanization. In this study, seasonal urban area were analyzed eight Asian mega from 1992–2012. The results indicate change pattern of varies different seasons. increased as size increased. Furthermore, dependency economic situation was also demonstrated. With respect seasons,...
Abstract Although bevacizumab (BVZ), a representative drug for anti-angiogenesis therapy (AAT), is used as first-line treatment patients with glioblastoma (GBM), its efficacy notably limited. Whereas several mechanisms have been proposed to explain the acquisition of AAT resistance, specific underlying yet be sufficiently ascertained. Here, we established that inhibitor differentiation 1 (ID1) high /activin A cell confers resistance BVZ. The bipotent effect activin during active phase was...
Abstract Development projects disrupt natural processes and species movement, leading to habitat alteration fragmentation, which ultimately results in biodiversity loss. These impacts can be mitigated by establishing land-use plans that minimize the effects on ecological connectivity(EC) implementing appropriate mitigation measures during project planning phase. To address this, this study aimed identify factors influencing changes EC due development determine extent of EC. By comparing a...
Abstract Background: Cancer treatments engender the risk of long-term cardiometabolic and cardiac conditions among survivors childhood cancer. However, underlying biological mechanisms remain unclear. This study aimed to identify DNA methylation (DNAm) CpG sites associated with factors (CMRFs) adverse outcomes, assess if these DNAm mediate associations between specific cancer outcomes. Methods: We included 3, 044 (median age at blood draw: 29.6 years) from St. Jude Lifetime Cohort....
Abstract Background: Social determinants of health (SDOH) are increasingly recognized as critical factors in shaping long-term adverse outcomes among childhood cancer survivors (survivors) because long-lasting toxicities from treatment may be exacerbated by social adversity. Our previous epigenetic study SDOH primarily focused on European ancestry, using measures such educational attainment, personal income, and the Area Deprivation Index. This aims to enhance understanding biological...
Best management practices (BMPs) are widely applied to address water quality degradation issues attributed non-point source pollutants. The objective of this study was assess the efficiency two types BMPs, vegetation filter strips (VFS) and wetlands, in reducing total nitrogen (TN) phosphorus (TP) a watershed, investigate whether BMPs is maintained under future climate scenarios by employing Soil Water Assessment Tool (SWAT). A set parameters calibrated using SWAT Calibration Uncertainty...
Urban forests play a critical role in addressing various urban environmental challenges, such as mitigating climate change, enhancing biodiversity, and improving habitat connectivity. To optimize the spatial allocation management of forests, it is essential to consider both impacts (e.g., carbon emissions resource consumption) ecosystem services storage quality)(Chaplin-Kramer et al., 2017). In this context, study employs Life Cycle Assessment (LCA) evaluate costs associated with forest...
Carbon storage in terrestrial ecosystems plays a vital role climate control. However, urban expansion and damage to natural areas, especially the rise of megalopolises, have affected carbon storage. To mitigate this damage, various policies been established by international, domestic, local governments. This study focuses on establishment management environmental protection areas analyzes their impact The targets cities Gyeonggi-do province, South Korea, which make up representative...
Abstract Jagged1 (JAG1) is a Notch ligand that correlates with tumor progression. Not limited to its function as ligand, JAG1 can be cleaved, and intracellular domain translocates the nucleus, where it functions transcriptional cofactor. Previously, we showed (JICD1) forms protein complex DDX17/SMAD3/TGIF2. However, molecular mechanisms underlying JICD1-mediated aggressiveness remains unclear. Here, demonstrate JICD1 enhances invasive phenotypes of glioblastoma cells by transcriptionally...
This paper explores how the traditional incumbents coped with rapid transition provoked by disruptive innovation in South Korean retail industry. More specifically, study concentrates on challenges faced and their step-by-step attempts to deal disruption. Shinsegae affiliates SSG.COM were chosen as target companies for our descriptive study. is one of top three conglomerates Korea, owning various subsidiary brands. also its subsidiaries, first established online distribution channel...
Forest spatial information is regularly established and managed as basic data for national forest planning policy establishment. Among them, the grade of vegetation conservation shall be investigated evaluated according to value conservation. As collection field over large or remote areas difficult, unmanned aerial vehicles (UAVs) are increasingly being used this purpose. Consequently, there a need research on UAV-monitoring three-dimensional (3D) image generation techniques. In study, new...
According to the guidelines of Nagoya Protocol, species are now recognized as ‘resources’ and owned by each country, thereby emphasizing significance biological resources importance continuous efforts made systematically manage them. Despite these efforts, climate change, which influences climatic factors such temperature precipitation, is expected negatively impact struggle for conservation affecting species’ habitats. We aimed devise methodologies that could be utilized management...
Ecological damage refers to the reduction in value of environment due human activities such as development. The intensity ecosystem is worsening worldwide. Although importance restoration projects reduce increasing, they are difficult carry out, owing absence data and monitoring damaged areas. In this study, ecologically areas for South Korea were detected using remote sensing field surveys. For analysis, national standardized vector datasets Google Earth images used; surveys conducted from...
Toxin–antitoxin (TA) systems, which consist of an intracellular toxin and its antidote (antitoxin), are encoded by ubiquitous genetic modules in prokaryotes. Commonly, the activity a is inhibited antitoxin under normal growth conditions. However, antitoxins degraded response to environmental stress, toxins liberated from consequently induce cell death or arrest. In free-living prokaryotes, TA systems often present large numbers considered be associated with adaptation pathogenic bacteria...
Glioblastoma (GBM) is the most lethal brain cancer, causing inevitable deaths of patients owing to frequent relapses cancer stem cells (CSCs). The significance NOTCH signaling pathway in CSCs has been well recognized; however, there no NOTCH-selective treatment applicable with GBM. We recently reported that Jagged1 (JAG1), a ligand, drives receptor-independent via JAG1 intracellular domain (JICD1) as crucial signal renders CSC properties. Therefore, mechanisms regulating JICD1 should be...
This study analyzed consulation data for the environmental impact assessment consultation focusing on onshore wind power and solar generation projects, which make up largest share of renewable energy generation, to identify annual trends number cases by type. The GIS Database(DB) construction location characteristics existing complexes were analyzed. Based business code project name, consultations was 127, with another 7,700 showing sharp increases in both 2014 2017. By examining progress...
Environmental Impact Assessment (EIA) is a globally recognized tool for proactively managing dynamic development projects by identifying, predicting, and analyzing their environmental impact proposing preventative measures. However, public participation in EIA often remains one-directional limited to procedural hearings. To address this, technology-driven framework enhances involvement procedures. EIA-related newspaper articles from 1990 2022 were systematically collected reviewed via web...