A5101524424- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Glaucoma and retinal disorders
- Ocular Oncology and Treatments
- Intraocular Surgery and Lenses
- Lung Cancer Treatments and Mutations
- Esophageal Cancer Research and Treatment
- Cancer and Skin Lesions
- Advanced Electron Microscopy Techniques and Applications
- Ocular Diseases and Behçet’s Syndrome
- Near-Field Optical Microscopy
- Advanced Fluorescence Microscopy Techniques
- Cytomegalovirus and herpesvirus research
- Herpesvirus Infections and Treatments
- Ear and Head Tumors
- Skin Protection and Aging
- Radio Frequency Integrated Circuit Design
- Toxoplasma gondii Research Studies
- Advancements in PLL and VCO Technologies
- Breast Lesions and Carcinomas
- Appendicitis Diagnosis and Management
- Dermatology and Skin Diseases
- COVID-19 and healthcare impacts
- Ophthalmology and Visual Impairment Studies
Soochow University
2025
Second Affiliated Hospital of Soochow University
2025
The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
2025
Zhejiang University
2014-2024
Second Affiliated Hospital of Zhejiang University
2018-2024
Sir Run Run Shaw Hospital
2014-2024
Blood Center of Zhejiang Province
2022-2023
Jiangsu Cancer Hospital
2019
Nanjing Medical University
2019
Zhejiang Chinese Medical University
2018
Abstract Background To report on corneal endothelial regeneration, graft clarity, and vision recovery when using endothelium-free grafts. Methods We evaluated the donor’s cell viability trypan blue staining dual with calcein acetoxy methyl ester ethidium homodimer-1. preserve eyeball integrity, we performed therapeutic penetrating keratoplasty cryopreserved donor tissue without endothelium 195 consecutive patients who suffered from perforation due to progressive primary disease such as...
To assess the tear meniscus height (TMH), noninvasive breakup time (NITBUT), and bulbar redness in pediatric patients after orthokeratology (OK).Pediatric who underwent overnight OK between December 2014 November 2017 were retrospectively investigated. According to of wearing, subjects divided into three groups: 1-week, 1-month, over 1-year. Age-matched recruited as a control group. Keratograph 5M was used TMH, NITBUT-first, NITBUT-average, score.A total 106 aged from 7 15 years included....
Keratoconus normally presents as a sporadic disease. Although different studies have found sequence variants of the visual system homeobox 1 (VSX1) gene associated with keratoconus in humans, no research has detected such patients from China. To investigate possibility VSX1 being candidate susceptibility for Chinese keratoconus, we performed screening this patients.Whole DNA was obtained leukocytes peripheral venous blood 50 and control subjects without ocular disorder. Polymerase chain...
Rationale: In the past decade, epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) treatment had been an important therapy for treating advanced EGFR-mutated lung cancer patients. However, a large number of these patients with EGFR-TKIs always acquired resistance to drugs in one year. The histologic transformation is mechanism. Patient concerns: Here we reported 41-year-old man adenocarcinoma and he showed both small-cell (SCLC) squamous cell carcinoma (SCC) after...
Stimulated emission depletion (STED) fluorescence nanoscopy allows the three-dimensional (3D) visualization of nanoscale subcellular structures, providing unique insights into their spatial organization. However, 3D-STED imaging and quantification dense features are obstructed by low signal-to-background ratio (SBR) resulting from optical aberrations out-of-focus background. Here, combining adaptive optics elements, we present an easy-to-implement, flexible, effective method to improve SBR...
Objective: To assess the application of Keratograph 5M in evaluating tear film and meibomian gland function patients with dry eye. Methods: A total 144 eyes were recruited study, which 72 from diagnosed eye healthy subjects. All subjects finished following tests or examinations:ocular surface disease index (OSDI) to evaluate symptoms; examination obtain meniscus height (TMH), noninvasive break-up time (NIBUT) including first NIBUT (NIBUT-Fir) average (NIBUT-Ave), infrared meibography;...
Herpes simplex virus type 1 (HSV-1) Keratitis (HSK) is a highly prevalent eye disease worldwide, characterized by lifelong recurrent episodes and major risk of leading to blindness. Detecting HSV-1 promptly accurately can initiate timely appropriate therapeutic regimen, minimizing tissue damage preventing vision impairment. Currently, PCR the most reliable method for identifying HSV-1, but its utilization point-of-care (POC) detection limited due need sophisticated equipment, particularly in...
To report clinical and histopathological characteristics of postoperative amyloidosis recurrence in a patient with lattice corneal dystrophy (LCD) type I.The manifestation recurrent the residual stroma was delineated LCD I after deep lamellar keratoplasty (DLKP) for 6.5 years. Complete removal recipient regrafting new cryopreserved donor button were accomplished by secondary DLKP. The primary DLKP graft underlying obtained examined analysis histopathologic ultrastructural changes.A...
To describe a case of Descemet's membrane detachment and schisis (Descemet's separated into multiple layers) with confirmation by high-definition anterior segment optical coherence tomography (AS-OCT) after phacoemulsification intraocular lens implantation.A 72-year-old woman presented persistent corneal edema phacoemulsification. She was diagnosed herpes simplex keratitis had been unsuccessfully treated for 60 days in her local hospital. Slit-lamp examination revealed moderate conjunctival...