A5101560433- Tryptophan and brain disorders
- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Mental Health Research Topics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Genetics and Neurodevelopmental Disorders
- Autism Spectrum Disorder Research
- Maternal Mental Health During Pregnancy and Postpartum
- Stress Responses and Cortisol
- Health, psychology, and well-being
- Health disparities and outcomes
- Circadian rhythm and melatonin
- Posttraumatic Stress Disorder Research
- Child Abuse and Trauma
- Resilience and Mental Health
- Emotional Labor in Professions
- Attention Deficit Hyperactivity Disorder
- Work-Family Balance Challenges
- Sleep and related disorders
- Health and Wellbeing Research
- Child and Adolescent Psychosocial and Emotional Development
- Epilepsy research and treatment
- Psoriasis: Treatment and Pathogenesis
- Wnt/β-catenin signaling in development and cancer
- Health Policy Implementation Science
Ansan University
2016-2023
Korea University
2012-2023
Catholic University of Korea
2023
University Radiology
2013
Los Alamos National Laboratory
2010-2011
Objective This study aimed to demonstrate that the Patient Health Questionnaire (PHQ)-8 is not less useful than PHQ-9 as a screening test for major depressive disorder (MDD). Methods We performed retrospective analysis of 567 patients in psychiatric outpatient units. The Mini International Neuropsychiatric Interview was used diagnose MDD. derived validity and reliability PHQ-8 PHQ-9. To evaluate ability discriminate MDD, we drew receiver operating characteristic (ROC) curves compared areas...
Abstract Background The Patient Health Questionnaire-9 (PHQ-9) has been standardized in several populations and is widely used clinical practice health care. However, it not appropriately the Korean general population, no normative data have presented. aim of this study was to provide psychometric properties PHQ-9 nationally representative population Korea. Methods We nationwide cross-sectional survey Korea from 2014 2016. 10,759 individuals aged over 19 years were analyzed study. As...
Abstract Recent studies have reported that methylation of the brain-derived neurotrophic factor ( BDNF ) gene promoter is associated with major depressive disorder (MDD). This study aimed to investigate association between cortical thickness and promoters as well serum levels in MDD. The participants consisted 65 patients recurrent MDD age- gender-matched healthy controls. Methylation were compared groups. right medial orbitofrontal, lingual, lateral occipital, left pars triangularis,...
Cytokines are believed to have a role in the pathophysiology of major depression. The alteration levels pro-inflammatory cytokines [interleukin 1β (IL-1β), IL-2, IL-6, IL-12, interferon γ, and tumor necrosis factor α] depression supports cytokine hypothesis this illness. IL-23 IL-17 also cytokines, but few studies focused on their This study investigated potential axis depression.Plasma were measured 26 depressive disorder (MDD) patients before after 6-week treatment with antidepressants;...
An increased prevalence of disabilities is being observed as more preterm infants survive. This study was conducted to evaluate correlations between brain MR imaging measurements taken at a term-equivalent age and neurodevelopmental outcome 2 years' corrected among very low-birth-weight infants.Of the various obtained ages, reproducible transcerebellar diameter anteroposterior length corpus callosum on sagittal images were compared with outcomes evaluated by Bayley Scales Infant Development...
Immunological control of hepatitis C virus (HCV) is possible and probably mediated by host T-cell responses, but the genetic diversity poses a major challenge to vaccine development. We considered monovalent polyvalent candidates for an HCV vaccine, including natural, consensus synthetic 'mosaic' sequence cocktails. Mosaic reagents were designed using computational approach first applied demonstrated experimentally human immunodeficiency type 1 (HIV-Δ). proteins resemble natural proteins,...
Abstract Background Clinical guidelines can improve health-care delivery, but there are a number of challenges in adopting and implementing the current practice for depression. The aim this study was to determine clinical experiences perceived barriers implementation these psychiatric care. Methods A web-based survey conducted with 386 specialists inquire about attitudes related depression influencing use guidelines. Quantitative data were analyzed, qualitative transcribed coded manually....
Although several previous studies have examined the association between late-life depression and blood adipokine levels, a marker of chronic inflammation, no comprehensively considered effects metabolic syndrome, which is known to affect levels. This study levels in geriatric after adjusting for syndrome.Participants were selected from Ansan Geriatric Study (depression group [n = 76] control 76]). Blood concentrations four adipokines (adiponectin, resistin, neutrophil-gelatinase-associated...
Hemorrhagic fever viruses (HFVs) are a diverse set of over 80 viral species, found in 10 different genera comprising five families: arena-, bunya-, flavi-, filo- and togaviridae. All these highly variable evolve rapidly, making them elusive targets for the immune system vaccine drug design. About 55 000 HFV sequences exist public domain today. A central website that provides annotated analysis tools will be helpful to researchers worldwide. The sequence database collects stores data...
Sang Won Jeon, Changsu Han, Young-Hoon Ko, Seo Young Yoon, Chi-Un Pae, Joonho Choi, Yong Chon Park, Jong-Woo Kim, Ho-Kyoung Seung-Duk Ashwin A. Patkar, and Mark Zimmerman. Clin Psychopharmacol Neurosci 2017;15:28-34. https://doi.org/10.9758/cpn.2017.15.1.28
The aim of the present study was to examine association between serotonin-related gene polymorphisms and bipolar disorder in Korean population. In addition, we sought explore relationship clinical characteristics patients polymorphisms.Inpatients with (n=103) control subjects (n=86) were genotyped for 5HT2A 1438A/G, tryptophan hydroxylase 1 (TPH1) 218 A/C, TPH2 703G/T. We divided into two groups according presence psychotic symptoms. severity their symptoms measured using Young Mania Rating...
This study aimed to evaluate the psychometric properties of Korean version Clinically Useful Anxiety Outcome Scale (CUXOS) and examine current diagnostic comorbidity differential severity anxiety symptoms between major depressive disorder (MDD) disorders.In total, 838 psychiatric outpatients were analyzed at their intake appointment. Diagnostic characteristics examined using structured clinical interview from DSM-IV because DSM5 was not available start study. The CUXOS score measured...
This study aimed at exploring the psychometric characteristics of Korean Version Depression and Somatic Symptoms Scale (DSSS) in a clinical sample, investigating impact somatic symptoms on severity depression.Participants were 203 consecutive outpatients with current major depressive disorders (MDD) or lifetime diagnosis MDD.The DSSS was compared Montgomery-Åsberg Rating (MADRS) 17-items Hamilton (HAMD).The showed two-factor structure that accounted for 56.8% variance, as well excellent...