A5100630483- Osteoarthritis Treatment and Mechanisms
- Psoriasis: Treatment and Pathogenesis
- Inflammatory mediators and NSAID effects
- Carcinogens and Genotoxicity Assessment
- Dermatology and Skin Diseases
- Cytokine Signaling Pathways and Interactions
- Bone fractures and treatments
- Urticaria and Related Conditions
- Asthma and respiratory diseases
- Health, Environment, Cognitive Aging
- Orthopaedic implants and arthroplasty
- Knee injuries and reconstruction techniques
- Rheumatoid Arthritis Research and Therapies
- Climate Change and Health Impacts
- Advanced Neural Network Applications
- Musculoskeletal pain and rehabilitation
- EEG and Brain-Computer Interfaces
- Stroke Rehabilitation and Recovery
- Advanced Fiber Laser Technologies
- Advancements in Battery Materials
- Autoimmune Bullous Skin Diseases
- Optical Imaging and Spectroscopy Techniques
- Nonlinear Photonic Systems
- DNA Repair Mechanisms
- Advanced Image and Video Retrieval Techniques
Second Affiliated Hospital of Zhejiang University
2012-2025
Shanghai University of Traditional Chinese Medicine
2016-2025
Shuguang Hospital
2016-2025
Yueyang Hospital
2024
Nanjing University of Science and Technology
2024
Chinese Academy of Sciences
2022-2024
Guangzhou Medical University
2019-2024
First Affiliated Hospital of Guangzhou Medical University
2023-2024
University of Science and Technology of China
2024
Changchun Institute of Applied Chemistry
2024
Object detection on UAV images is a recent research hotspot. Existing object methods have achieved good results general scenes, but there are inherent challenges with images. The accuracy of limited by complex backgrounds, significant scale differences, and densely arranged small objects. To solve these problems, we propose image network based Self-attention Guidance Multi-scale Feature fusion (SGMFNet). Firstly, design Global-Local module (GLFG). This can effectively combine local...
Objective: Mask plays an important role in preventing infectious respiratory diseases. The influence of wearing masks physical exercise on the human body needs to be studied. purpose this study is explore surgical cardiopulmonary function healthy people during exercise. Methods: physiological responses 71 subjects (35 men and 36 women, age 27.77 ± 7.76 years) exercises with without (mask-on mask-off) were analyzed. Cardiopulmonary metabolic reaction measured by test (CPET). All tests carried...
Objective. To assess the short-term efficacy and safety of two kinds Traditional Chinese herbal patches, Fufang Nanxing Zhitong Gao (FNZG) Shangshi Jietong (SJG), for painful knee osteoarthritis (OA). Methods. Patients were randomly enrolled in a double-blind, placebo-controlled study to receive FNZG (n = 60), SJG or placebo patch 30) 7 days. Outcome measures included visual analogue scale (VAS), Western Ontario McMaster Universities Osteoarthritis Index (WOMAC), Medicine Syndrome...
<title>Abstract</title> Psoriasis is a chronic, complex immune-mediated inflammatory disorder with cutaneous and systemic manifestations in which keratinocytes, dendritic cells T have central roles. UBE2L3 may be protective biomarker that regulates the pathogenesis of psoriasis. Here, we identified IL-17A signaling similarity between human psoriatic skin <italic>Ube2l3</italic> conditional knockout mouse epidermis rather than dermis. was regulated by CXCR6<sup>+</sup> Vγ2<sup>+ </sup>γδT...
Abstract Tissue-resident memory T (TRM) cells are a recently defined subtype of non-recirculating with longevity and protective functions in peripheral tissues. As an essential frontline defense against infections, TRM have been reported to robustly patrol the tissue microenvironment malignancies. Accumulating evidence also implicates that relapse chronic inflammatory skin diseases such as psoriasis vitiligo. In light these developments, this review aims synthesize recent findings enhance...
To investigate the characteristics of Vitamin D (VitD) and bone metabolism in patients with knee osteoarthritis (KOA) concurrent osteoporosis (OP). A retrospective analysis was performed on 240 who were admitted to orthopedics department between March 2019 2024. Patients stratified into four distinct groups according their respective disease categories.There 90 simple KOA group, comprising 13 males 77 females, age ranged from 50 91 years old an average (68.48±8.96) old. There OP 7 83 52 88...
Previous studies have shown that patients with chronic obstructive pulmonary disease (COPD) of severe or very airflow limitation a reduced pectoralis muscle area (PMA), which is associated mortality. However, whether COPD mild moderate also PMA remains unclear. Additionally, limited evidence available regarding the associations between and respiratory symptoms, lung function, computed tomography (CT) imaging, function decline, exacerbations. Therefore, we conducted this study to evaluate...
Abstract Theoretically, a haplotype has higher level of heterozygosity than individual single nucleotide polymorphism (SNP) and the association study based on may have an increased power for detecting disease associations compared with SNP-based analysis. In this study, we investigated effects four haplotype-tagging SNPs (htSNP) inferred pairs X-ray cross-complementing group 1 (XRCC1) gene chromosome damage detected by cytokinesis-block micronucleus assay. The included 141 coke-oven workers...
Abstract DNA repair is an essential mechanism for cells to maintain their genomic integrity under endogenous or exogenous assault. Reduced capacity (DRC) associated with increased risk several environmentally related cancers. The micronucleus in peripheral lymphocytes has been validated as a biomarker of chromosomal damage, increasing cancer human populations. We hypothesized that suboptimal DRC the increase damage among 94 coke-oven workers and 64 noncoke-oven controls. was evaluated...
Objective: It is known that bone healing delayed in the presence of osteoporosis humans. However, due to complexities osteoporotic fractures, animal models may be more appropriate for studying effects detail and testing drugs on fracture repair process. The purpose this study was investigate influence ovariectomy-induced osteopenia an open femoral osteotomy model, test feasibility model evaluating process under osteopenic conditions. Methods: Ovariectomized (OVX) mouse were employed assess...
Magnesium-based metals are promising for biomedical use its biodegradation characteristic. However, rapid degradation in physiological environment impedes application. Oxides coating is a widely-used form of surface modification to improve the corrosion resistance biomaterials. In this study, we systematically compared two oxides coatings, steam oxidation (SO) and micro-arc (MAO), controlling improving biocompatibility pure magnesium vitro vivo. The addition both coatings was found reduce...
To date, the anti-gravity treadmill (AlterG), as a representative method of Lower body positive pressure (LBPP) treadmills, has been rarely reported for knee osteoarthritis (KOA) rehabilitation. The purpose this case study was to setup clinical protocol example AlterG intervention on KOA and evaluate treatment effectiveness by 3D gait analysis combined with free EMG explore kinematic parameter changes.A 65-year-old female patient (BMI = 26, mild obesity) undergoing "more than 7 years KOA."...
Noise-induced hearing loss (NIHL) is the second-most frequent form of sensorineural loss. When exposed to same noise, some workers develop NIHL while others do not, suggesting that may be associated with genetic factors. To explore relationship between single nucleotide polymorphisms (SNPs) in heat shock protein 70 (HSP70) genes (HSPA1A, HSPA1B and HSPA1L) susceptibility Han Chinese a case-control association study was carried out 286 cases matched gender, age, type work, exposure time,...
Background/Aims: Cartilage destruction is thought to be the major mediator of osteoarthritis. Recent studies suggest that inhibition subchrondral bone loss by anti-osteoporosis (OP) drug can protect cartilige erosion. Osthole, as a promising agent for treating osteoporosis, may show potential in The purpose this study was investigate whether Osthole affects proliferation and catabolism rat chondrocytes, degeneration cartilage explants. Methods: Rat chondrocytes were treated with (0 μM, 6.25...
Anti-tumor necrosis factor alpha (TNF- α) therapy has made a significant impact on treating psoriasis. Despite these agents being designed to block TNF- α activity, their mechanism of action in the remission psoriasis is still not fully understood at molecular level. To better understand mechanisms Anti-TNF- therapy, we analysed global gene expression profile (using mRNA microarray) peripheral blood mononuclear cells (PBMCs) that were collected from 6 patients before and 12 weeks after...