A5048435698- Food Drying and Modeling
- Microbial Inactivation Methods
- Reproductive Biology and Fertility
- Plant nutrient uptake and metabolism
- Testicular diseases and treatments
- Sodium Intake and Health
- Renal and related cancers
- Sperm and Testicular Function
- Freezing and Crystallization Processes
- Gastric Cancer Management and Outcomes
- Pregnancy and preeclampsia studies
- Growth Hormone and Insulin-like Growth Factors
- Trace Elements in Health
- Cancer-related molecular mechanisms research
- Ovarian function and disorders
- Diet and metabolism studies
- Colorectal Cancer Screening and Detection
- Electronic Packaging and Soldering Technologies
- Immunotherapy and Immune Responses
- Radiation Effects and Dosimetry
- Genetic Syndromes and Imprinting
- Indoor Air Quality and Microbial Exposure
- Pregnancy-related medical research
- Listeria monocytogenes in Food Safety
- Galectins and Cancer Biology
China Medical University
2012-2025
National Health and Family Planning Commission
2025
Third Affiliated Hospital of Guangzhou Medical University
2023-2025
Guangzhou Medical University
2018-2025
First People's Hospital of Yunnan Province
2024
First Hospital of China Medical University
2024
Northwest A&F University
2023-2024
Tianjin University of Traditional Chinese Medicine
2023
Suzhou Municipal Hospital
2022
Nanjing Medical University
2022
Objectives: Otitis media is one of the most important causes hearing loss at an early age. Effective vaccination with routine 7-valent pneumococcal conjugate vaccine (PCV-7) was introduced in 2000. It has been gradually replaced by nontypeable Haemophilus influenzae protein D or higher-valent 13-valent PCV (PCV-13) since 2010. Data on change otitis burden recent years are sparse global, regional, and national levels. Design: The Global Burden Disease 2019 study used to evaluate prevalence,...
// Xiu-Xia Wang 1 , Jing-Zan Wei Jiao Shu-Yi Jiang Da-Hai Yu and Da Li Department of Obstetrics Gynecology, Shengjing Hospital China Medical University, Shenyang, Correspondence: email: Wang, Keywords : DNA methylation profiling; expression epigenetic; PCOS Received July 5, 2014 Accepted 14, Published 16, Abstract Polycystic ovary syndrome (PCOS) is one the most common endocrine disorders in women. However, epigenetic mechanism involved progression remains largely unknown. Here, combining...
Plastic pollution is an emerging environmental issue, with microplastics and nanoplastics raising health concerns due to bioaccumulation. This work explored the impact of polystyrene nanoparticle (PS-NPs) exposure during prepuberty on male reproductive function post maturation in rats. Rats were gavaged PS-NPs (80 nm) at 0, 3, 6, 12 mg/kg/day from postnatal day 21 95. accumulated testes reduced sperm quality, serum hormones, testicular coefficients. HE staining showed impaired...
N6-methyladenosine (m6A) RNA modifications have emerged as crucial epigenetic regulators in various biological processes, including spermatogenesis. This review aims to elucidate the role of m6A spermatogenesis and their implications for male infertility, particularly non-obstructive azoospermia (NOA). We conducted a comprehensive recent studies focusing on methyltransferases, demethylases, reader proteins involved Our analysis reveals that play vital regulating mRNA stability, translation...
This cross-sectional study was conducted to examine the association between ratio of non-high-density lipoprotein cholesterol high-density (NHHR) and metabolic dysfunction-associated steatotic liver disease (MASLD), particularly in populations with obesity type 2 diabetes (T2D). The analysis included 3784 participants who were 20 years older, using data from National Health Nutrition Examination Survey (NHANES) 2017–2018. prevalence MASLD determined multivariable logistic regression...
Abstract Background This cross-sectional study aims to explore whether there exists an interaction between selenium and menopause concerning type 2 diabetes (T2D) prevalence its related indicators such as fasting blood glucose (FBG) homeostasis model assessment of insulin resistance (HOMA-IR). Methods 150 women aged 35–60 years old were finally analyzed in this study. Multivariate linear or logistic regression modeling was conducted the association T2D besides indicators. Subgroup analyses...
Applications of the key plant nutrient nitrogen (N) increase uptake and accumulation pollutants such as polycyclic aromatic hydrocarbons (PAHs). However, it is unclear how a plant’s preference for particular form N in soil affects PAHs. In this study, we investigated physiological mechanisms involved fluoranthene by rice ( Oryza sativa L.) wheat Triticum aestivum examined these were affected different forms treatment under an equivalent supply. Both species uptake. Rice accumulated more than...
Vascular endothelial growth factor C (VEGF-C) accelerates cervical cancer metastasis, while the detailed mechanism remains largely unknown. Recent evidence indicates that microRNA play a crucial role in controlling cell invasiveness. In present study, we investigated of miR-326 VEGF-C-induced invasion. VEGF-C expression was higher and much lower primary specimens than non-cancerous specimens, negative correlation between found. On carcinoma line SiHa cells, treatment with downregulated level...
Sterility induced by anti-cancer treatments has caused significant concern, yet the mechanism and treatment exploration are little for male infertility after cancer therapy. Busulfan, antineoplastic that was widely applied before bone marrow transplantation, known to induce reproductive disorder.To investigate effect of busulfan on blood-testis barrier function in adult rats determine whether noncollagenous 1 domain peptide, biologically active fragment proteolyzed from collagen α3 chain...
In the testis, spermatocytes and spermatids rely on lactate produced by Sertoli cells (SCs) as energy source. Transforming growth factor-beta 3 (TGF-β3) is one of generally accepted paracrine regulatory factors SC-created blood-testis barrier (BTB), yet its role in SC glycolysis production still remains unclear.To investigate effect TGF-β3 SCs determine lethal giant larvae 2 (Lgl2) Notch signaling activity during this process.Primary cultured rat TM4 were treated with different...
Infertility is defined as failure to achieve pregnancy within 12 months of unprotected intercourse in women. Trace elements, a kind micronutrient that very important female reproductive function, are affected by intestinal absorption, which regulated gut microbiota. Enterotype the classification an microbiome based on its characteristics. Whether or not Prevotella-enterotype and Bacteroides-enterotype associated with blood trace elements among infertile women remains unclear. The study aimed...
Background Although abdominal aortic aneurysm (AAA) is associated with life-threatening complications, there are still limited reliable biomarkers for diagnostic purpose. MicroRNAs (miRNAs) have been proposed as the potential and risk stratification markers of AAA patients, we aim to evaluate serum level miR-1-3p its value in AAA.
Transforming growth factor-β3 (TGF-β3) has been proved to perturb the blood-testis barrier (BTB) by accelerating junction protein endocytosis in Sertoli cells (SCs) accommodate traversing of preleptotene spermatocytes across BTB around stage VIII rat. Yet molecular network underlying impairment TGF-β3 on integrity is not fully elucidated. Our study herein was designed investigate participation microRNA-142-3p (miR-142-3p), which reported affect signaling via different pathways, during...
To determine the main clinical and demographic outcomes related to Pulmonary Hypertension (PH) adverse obstetric fetal/neonatal outcomes.This study retrospectively analyzed medical record data of 154 patients with PH who were admitted Third Affiliated Hospital Guangzhou Medical University between January 2011 December 2020.According severity elevated Artery Systolic Pressure (PASP), 82 women (53.2%) included in mild group, 34 (22.1%) moderate 38 (24.7%) severe group. There significant...
Autoimmune disorders are associated with gestational diabetes mellitus (GDM) in pregnant women who were positive for thyroid peroxidase antibody (TPOAb). Soluble CD40 ligand (sCD40L) and soluble interleukin-2 receptor (sCD25) abnormally expressed autoimmune diseases reliable markers of inflammation. The purpose this study was to evaluate sCD40L sCD25 early pregnancy investigate their correlation GDM TPOAb. A total 126 the first trimester enrolled analysis: 93 TPOAb 33 negative Demographical...
To assess carcinoembryonic antigen (CEA), carbohydrate 19-9 (CA19-9), platelet distribution width (PDW), neutrophil-to-lymphocyte ratio (NLR), and platelet-lymphocyte (PLR) for gastric cancer's (GC) diagnostic efficiency, the use of receiver operating characteristic curves (ROC) combined with logistic regression to evaluate multi-index combination's value GC. 773 GC patients' clinical data were retrospectively collected in Weihai Municipal Hospital, affiliated hospital Shandong University...
Hypertensive patients with higher ENaC genetic variation may experience greater SBP reductions by consuming low-sodium salt.