A5034062118- Bacterial Infections and Vaccines
- Pneumonia and Respiratory Infections
- Influenza Virus Research Studies
- Parasite Biology and Host Interactions
- Parasitic Diseases Research and Treatment
- Bacterial Identification and Susceptibility Testing
- SARS-CoV-2 detection and testing
- Nematode management and characterization studies
- Antimicrobial Resistance in Staphylococcus
- Infective Endocarditis Diagnosis and Management
- Viral Infectious Diseases and Gene Expression in Insects
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Microbial infections and disease research
- Genomics and Phylogenetic Studies
- Virology and Viral Diseases
- Cerebrospinal fluid and hydrocephalus
- Mycobacterium research and diagnosis
- RNA and protein synthesis mechanisms
- Infectious Diseases and Mycology
- Microbial Community Ecology and Physiology
- Protist diversity and phylogeny
- Cystic Fibrosis Research Advances
- Ocular Infections and Treatments
- Helicobacter pylori-related gastroenterology studies
Royal Hobart Hospital
2016-2024
University of Tasmania
2024
La Trobe University
2021
In 2015, a marked increase in vancomycin-resistant Enterococcus faecium (VREfm) isolation was detected at the Royal Hobart Hospital, Australia. The primary objective of this work to examine dynamics VREfm transmission using whole genome data mapped public health surveillance information. Screening and clinical isolates from patients were typed for specific vancomycin-resistance locus present. Of total collected 2014-2016 (n = 222), 15.3% 84.7% harboured either vanA or vanB locus,...
Pandoraea species have been isolated from diverse environmental samples and are emerging important respiratory pathogens, particularly in people with cystic fibrosis (CF). In the present study, two bacterial isolates initially recovered consecutive sputum collected a CF patient identified as pnomenusa underwent polyphasic taxonomic analysis. The were found to be Gram-negative, facultative anaerobic motile bacilli subsequently designated strains 6399T (=LMG29626T=DSM103228T) 7641...
Nontypeable Haemophilus influenzae (NTHi) colonizes human upper respiratory airways and plays a key role in the course pathogenesis of acute exacerbations chronic obstructive pulmonary disease (COPD). Currently, it is not possible to distinguish COPD isolates NTHi from other clinical using conventional genotyping methods. Here, we analysed core accessory genome 568 isolates, including 40 newly sequenced look for genetic distinctions between with respect illnesses, otitis media, meningitis...
Pandoraea species are considered as emerging pathogens in people with cystic fibrosis (CF). The contribution of these organisms to disease progression CF patients is not fully understood owing large measure the scant reports clinical and research literature describing their colonization associated virulence determinants. In an effort increase awareness evidence for spp. infection CF, stimulate aimed at unraveling pathogenic properties Pandoraea, we report a case 26-year-old Australian...
© 2024 The Author(s) (or their employer(s)). Published by CSIRO Publishing on behalf of the ASM. This is an open access article distributed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND)
Abstract Objectives There is clinical uncertainty over the optimal treatment for penicillin-susceptible Staphylococcus aureus (PSSA) infections. Furthermore, there concern that phenotypic penicillin susceptibility testing methods are not reliably able to detect some blaZ-positive S. aureus. Methods Nine isolates, including six genetically diverse strains harbouring blaZ, were sent in triplicate 34 participating laboratories from Australia (n = 14), New Zealand 6), Canada 12), Singapore 1)...
Abstract We report a case of myositis in male patient Australia who had progressive weakness and wasting his left lower limb. Although clinical, pathologic, laboratory assessments were inconclusive, new, nested PCR–coupled sequencing method enabled the unequivocal diagnosis caused by enigmatic nematode Haycocknema perplexum.
Abstract Background In Australia, invasive meningococcal disease (IMD) incidence rapidly increased between 2014 and 2017 due to rising serogroup W (MenW) MenY infections. We aimed better understand the genetic diversity of IMD during 2018 using whole genome sequencing data. Methods Whole data from 440 Australian isolates collected 1737 international MenW:CC11 in Europe, Africa, Asia, North America, South America 1974 2020 were used phylogenetic analyses; relatedness was determined...
Nontypeable Haemophilus influenzae (NTHi) is an important cause of human illness, including pneumonia and acute exacerbations chronic obstructive pulmonary disease (COPD). We report here the draft genome isolate NTHi collected from sputum a patient presenting with COPD in Tasmania, Australia.
Mycobacterium chelonae keratitis is rare and difficult to treat. This the first known case worldwide of effective treatment using intrastromal amikacin injections in a corneal transplant recipient who had metastatic breast cancer. The challenges principles management, applicable other causes infective keratitis, are reviewed.
Healthcare facilities are high-risk settings for coronavirus disease 2019 (COVID-19) transmission. Early in the COVID-19 pandemic, first large healthcare-associated outbreak within Australia occurred Tasmania. Several operational research studies were conducted amongst workers from implicated hospital campus, to learn more about transmission.Healthcare (HCWs) campus invited complete an online survey and participate a serology study. Blood samples serological testing collected at...
Recurrence is a characteristic feature of Nontypeable <i>Haemophilus</i> influenzae (NTHi) infection, particularly during COPD exacerbations, which makes management difficult. Recurrent infections are caused either by relapse from persistence earlier infection or new with an exogenous strain. Whole genome sequencing provides the ultimate resolution to differentiate between strains and existing infections. However, lack simple workflow for genome-wide pairwise comparison paired isolates still...