- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Medical Imaging and Analysis
- Myofascial pain diagnosis and treatment
- Ferroptosis and cancer prognosis
- Cancer Cells and Metastasis
- Spinal Fractures and Fixation Techniques
- Immune cells in cancer
- Pluripotent Stem Cells Research
- 3D Printing in Biomedical Research
- Cervical and Thoracic Myelopathy
- Drug Transport and Resistance Mechanisms
- AI in cancer detection
- Climate variability and models
- Soil Mechanics and Vehicle Dynamics
- Soil and Unsaturated Flow
- Advanced Graph Neural Networks
- Neuroinflammation and Neurodegeneration Mechanisms
- Muscle activation and electromyography studies
- Cognitive Computing and Networks
- Groundwater flow and contamination studies
- Advanced Malware Detection Techniques
- Software Testing and Debugging Techniques
- Anesthesia and Sedative Agents
- Hydrology and Drought Analysis
Nanjing University of Posts and Telecommunications
2024
Helmholtz-Zentrum Dresden-Rossendorf
2023
Chinese People's Armed Police Force
2022-2023
Chinese People's Armed Police General Hospital
2023
Tongji University
2022
Shanghai Pulmonary Hospital
2022
Shenzhen Second People's Hospital
2017-2020
Hubei Polytechnic University
2020
Shenzhen University
2010-2019
Zhengzhou University of Science and Technology
2019
With the increasing popularity of Android platform, malware, especially APP-Repackaging malware wherein malicious code is injected into legitimate applications, spreading rapidly. This paper proposes a new system named MIGDroid, which leverages method invocation graph based static analysis to detect malware. The reflects "interaction" connections between different methods. Such can be naturally exploited because and applications are expected weak. Specifically, MIGDroid first constructs on...
Sepsis-associated encephalopathy (SAE) is a cognitive impairment caused by sepsis, associated with increased morbidity and death. And acetaminophen (APAP) promising therapeutic medicine for SAE treatment. This research was designed to determine whether APAP alleviates attenuating ferroptosis mediating the glutathione peroxidase (GPX4) pathway. The cecal ligation puncture (CLP) approach used establish septic mouse models. survival rates 7 days were determined. Morris water maze (MWM) utilized...
Neuronal ferroptosis is a major cause of cognitive impairment and mortality in patients with sepsis-associated encephalopathy (SAE). A low dose acetaminophen (APAP) septic mice can prevent the hippocampal tissue; however, underlying mechanism unknown. This study aimed to investigate by which APAP reduces tissues mice.A mouse model SAE was established, pathway inhibitors RSL3 iFSP1+RSL3 were used addition for interventions, respectively. The 7-day survival rate recorded, function examined...
Low back pain (LBP) is a common problem that can contribute to motor dysfunction. Previous studies reporting the changes in kinematic characteristics caused by LBP present conflicting results. This study aimed apply multisegmental spinal model investigate patients with lumbar disc herniation (LDH) during five activities of daily living (ADLs). Twenty-six healthy subjects and 7 LDH participated this performed level walking, stair climbing, trunk flexion, ipsilateral contralateral pickups. The...
Objective: Propofol-based sedation has been widely used for gastroscopy, but the risk of respiratory suppression in elderly patients should not be overlooked. Intravenous (IV) lidocaine during surgery can reduce demand propofol and incidence cardiopulmonary complications. We examined whether IV reduces dose occurrence adverse events gastroscopy patients. Methods: conducted a prospective, single-center, double-blind randomized controlled trial aged ≥ 65 years with ASA I-II. Subjects were...
The main purpose of this study was to investigate the compensatory response muscle activities seventeen major groups in spinal region, intradiscal forces five lumbar motion segment units (MSUs), and facet acting on ten joints patients with disc herniation (LDH). Twenty-six healthy adults seven LDH performed trunk flexion, ipsilateral picking up, contralateral up sequence. Eight optical markers were placed landmarks pelvis process. coordinates these captured drive a musculoskeletal model...
BACKGROUND People with low back pain (LBP) alter their motion patterns during level walking and stair climbing due to or fear. However, the alternations of load sharing two activities are largely unknown. The objective this study was investigate effect LBP caused by lumbar disc herniation (LDH) on muscle 17 main trunk groups intradiscal forces acting five discs. MATERIAL AND METHODS Twenty-six healthy adults seven LDH patients were recruited perform in Gait Analysis Laboratory. Eight optical...
Abstract Background To introduce a novel robotic system ‘Orthbot’ that has been developed and tested as surgical assistant for auto‐placement of the K‐wire in lumbar fusion. Methods This is multi‐centre, randomized controlled clinical study includes 56 patients (robot group, RG: 27, free‐hand FG: 29). Following pre‐operative planning intra‐operative fluoroscopic images, automatically completed registration placement under supervision surgeon. Deviation distance (DD) deviation angle (DA) were...
Low back pain (LBP) continues to be a severe global healthy problem, and lot of patients would undergo conservative or surgical treatments. However, the improving capacity spinal load sharing during activities daily living (ADLs) after interventions is largely unknown. The objective this study was quantitatively predict improvement musculoskeletal loadings level walking stair climbing two simulated interventions. Twenty-six adults seven lumbar disc herniation performed in sequence. movement...
<strong>BACKGROUND</strong> Center of rotation (COR) has been used for assessing spinal motion quality. However, the biomechanical influence COR deviation towards different directions during flexion-extension (FE) remains largely unknown. This study aimed to investigate alteration in range (ROM), compressive force, shear and neutral zone size (NZ) a lumbar functional unit (FSU), caused by deviated FE. <strong>MATERIAL AND METHODS</strong> Twelve human cadaveric FSUs (6 L2-L3, 6 L4-L5) were...
Abstract Under the background of continuous development new engineering, more and researches are aiming at cutting-edge technologies, among which industrial robots have attracted much attention. Based on typical trajectory a given load condition palletizing robot, dynamics analysis calculation was accomplished by using module Adams software under that robot working normally, then obtained dynamic variation when rolling bearing running, furthermore, contact stress change rule finite element...
In a recent analysis of 25 CMIP6 models, Gr&#252;ndemann et al. (2022, https://doi.org/10.1038/s43247-022-00558-8) have shown that by the end this century, daily land rainfall extremes could increase in magnitude between 10.5% and 28.2% for annual events (1 year return period), 13.5% 38.3% centennial (100 period). The higher relative larger period was consistent all climate models scenarios. However, study solely based on model output so far, finding not validated observations. Using...
The predictive power of numerical approaches for the analysis flow fields, e.g. &#160;radionuclide migration, depends on quality underlying pore network geometry. Validation obtained simulation results can only be performed with a limited number methods. Positron emission tomography (PET) is suitable technique that has been established in geomaterial sciences recent years. use radiotracers allows advective transport and diffusive flux variety complex porous materials. In addition to...
<div>Abstract<p>Low oxygen levels have been shown to promote self-renewal in many stem cells. In tumors, hypoxia is associated with aggressive disease course and poor clinical outcomes. Furthermore, tumors display gene expression signatures characteristic of human embryonic cells (hESC). We now tested whether might be responsible for the hESC signature observed tumors. show that hypoxia, through hypoxia-inducible factor (HIF), can induce an hESC-like transcriptional program,...
<div>Abstract<p>Low oxygen levels have been shown to promote self-renewal in many stem cells. In tumors, hypoxia is associated with aggressive disease course and poor clinical outcomes. Furthermore, tumors display gene expression signatures characteristic of human embryonic cells (hESC). We now tested whether might be responsible for the hESC signature observed tumors. show that hypoxia, through hypoxia-inducible factor (HIF), can induce an hESC-like transcriptional program,...
Background: Human movement consists of numerous degrees freedom (DOF). How the nervous system (NS) computes appropriate command to coordinate these DOFs finish specific tasks is still hotly debated. One common way simplify redundant multiple by combining them into units or synergies. The present study aimed investigate kinematic complexity five activities daily living (ADLs) and detect amount synergy during every ADL relationship motion pattern between ADLs. Method: Twenty-six able-bodied...