A5088067517- Geotechnical Engineering and Analysis
- Grouting, Rheology, and Soil Mechanics
- Civil and Geotechnical Engineering Research
- Tunneling and Rock Mechanics
- Geotechnical Engineering and Underground Structures
- Rock Mechanics and Modeling
- Geological Modeling and Analysis
- Advanced machining processes and optimization
- Geotechnical Engineering and Soil Stabilization
- Cryospheric studies and observations
- Geomechanics and Mining Engineering
- Geoscience and Mining Technology
- Regional Economic and Spatial Analysis
- Sirtuins and Resveratrol in Medicine
- Simulation and Modeling Applications
- Geochemistry and Geologic Mapping
- Cytokine Signaling Pathways and Interactions
- Structural Integrity and Reliability Analysis
- Osteoarthritis Treatment and Mechanisms
- Wound Healing and Treatments
- Advanced Numerical Analysis Techniques
- Grey System Theory Applications
- Manufacturing Process and Optimization
- Climate change and permafrost
- Forensic Entomology and Diptera Studies
Tongji University
2013-2025
Donghua University
2020-2024
Dalian Medical University
2012-2024
Second Affiliated Hospital of Dalian Medical University
2016-2024
Shanghai Tunnel Engineering (China)
2018-2019
Southwest Jiaotong University
2009-2010
Xihua University
2010
Chinese Academy of Sciences
2009
Shenyang Institute of Computing Technology (China)
2009
Loughborough University
2009
A reliable geological model plays a fundamental role in the efficiency and safety of mountain tunnel construction. However, regional models based on limited survey data represent macroscopic environments but not detailed internal characteristics, especially at portals with complex conditions. This paper presents comprehensive methodological framework for refined modeling surrounding rock subsequent mechanics analysis, particular focus natural space distortion hard-soft interfaces portals....
This paper introduces an Evolutionary Computing Control Strategy (ECCS) for the motion control of nonholonomic robots, and integrates ordinary differential equation (ODE)-based kinematics model with a nonlinear predictive (NMPC) strategy particle-based evolutionary computing (PEC) algorithm. The ECCS addresses key challenges traditional NMPC controllers, such as their tendency to fall into local optima when solving optimization problems, by leveraging global capabilities computation....
Activated STAT3 signaling is critical for human medulloblastoma cells. SHP2, SOCS3 and PIAS3 are known as the negative regulators of signaling, while their relevance to frequent activation in medulloblastomas remains unknown.Tissue microarrays were constructed with 17 tumor-surrounding noncancerous brain tissues 61 cases classic medulloblastomas, 44 large-cell 15 nodular which used immunohistochemical profiling STAT3, expression patterns frequencies nuclear translocation. Three cell lines...
Trans-resveratrol suppresses glioblastoma growth in vitro, but its effects on intracranial glioblastomas remain untested. Resveratrol crosses the blood-brain barrier, and lumbar puncture (LP) greatly increases bioavailability rat brains; therefore, we investigated effectiveness of LP-administered resveratrol orthotopic glioblastomas. Twenty-four tumor-bearing rats were separated into two groups: Group 1 receiving 100 μl saline containing 0.3% DMSO 2 (300 μM). Treatments started 3 days after...
Developing efficient materials for capturing and storing CO2 is crucial in addressing the environmental crisis caused by excessive emissions. This paper presents synthesis of amino-modified mesoporous carbon with high specific surface areas adsorption capabilities. The were synthesized using resol as source, F127 soft template agent, dicyandiamide material, a mixture ethanol water solvent. structure morphology characterized N2 adsorption/desorption, X-ray diffraction (XRD), Fourier transform...
Knee osteoarthritis (OA) is a common degenerative disease. Intra-articular administration of flurbiprofen frequently employed in clinic to treat OA, while repeated injections are required because the limited effective duration. To improve therapeutic outcome and prolong treatment interval, poly(ε-caprolactone-co-lactide)-b-poly(ethylene glycol)-b-poly(ε-caprolactone-co-lactide) (PCLA–PEG–PCLA) triblock copolymer based thermosensitive gel for sustained intra-articular drug delivery was...
Considering that the particular geometric shape of a quasi-rectangular shield, grout flowing law and its motion process are more complicated than those conventional circular shield. To interpret grouting mechanical ehaviour in special-shape shield tail void, filling diffusion mechanism synchronous was analysed. The is separated into two independent processes, which contains circumferential longitudinal diffusion. theoretical model pressure spatial distribution derived based on principle...
Wound measurement is an objective and direct way to trace the course of wound healing evaluate therapeutic efficacy. Nevertheless, accuracy efficiency current methods need be improved. Taking advantages reliability transparency tracing computer-aided digital imaging, a transparency-based imaging approach established, by which data from 340 were collected 6 experimental groups (8 rats/group) at 8 time points (Day 1, 3, 5, 7, 10, 12, 14 16) orderly archived onto model sheet. This sheet was...
Background and Aim: Glioblastoma multiforme (GBM) is a highly aggressive brain malignancy that lacks reliable treatments.Resveratrol possesses anti-cancer effects, but its activity against glioblastoma cells variable for unknown reasons.One mechanism through which drugs exert their effects oxidative damage caused by increased reactive oxygen species (ROS) production.Thus, the present study examined relationship between stress sensitivity to resveratrol in cells.Methods: Two GBM cell lines...
Anaplastic thyroid cancer/ATC is highly lethal malignancy without reliable chemotherapeutic drug. Resveratrol possesses anti-ATC activities but encounters resistance in some cases due to certain unknown reason(s).Because signal transducer and activator of transcription/STAT3 signaling critical for ATC cell survival the main molecular target resveratrol, its roles determining fates resveratrol-treated cells were investigated here.Human THJ-11T, THJ-16 THJ-21T lines treated by 100 μM...
Due to atmospheric scattering, solar radiation, and other factors, the Ice, Cloud, land Elevation Satellite-2 (ICESat-2) product data suffer from a substantial amount of background noise. This poses significant challenge when attempting directly utilize raw data. Consequently, denoising becomes an indispensable preprocessing step for its subsequent applications, such as extraction forest structure parameters ground elevation While Density-Based Spatial Clustering Applications with Noise...
Diabetic skin wound is a complex problem due to the disruption of normal repairing program and lack effective remedy. Lucilia sericata larvae (maggot) folk method treat chronic wound, while its therapeutic effects on that caused by diabetic remains unknown.
This article outlines the merits of proposed synchronous propulsion and assembly method in construction a long-distance tunnel. In traditional shield construction, stress unlooped segment during process is systematically overlooked. However, novel tunnel method, advancing force directly acts on segment, so safety unknown. this paper, focusing process, interactions concentrations under asymmetric effects are analysed detail via suite finite element models. The results show that mode segments...
Abstract In constructing super‐large section shield tunnels, it is difficult to guarantee the filling efficiency and uniformity of grouting behind segments. Studies on grout diffusion models often simplify process, leading inaccurate results, especially for tail void with special noncircular profiles. This paper presents a theoretical study mechanism its mechanical behaviour, particular focus actual motion process at synchronous stage when advancing. A semi‐elliptical surface compound model...