- Aquaculture Nutrition and Growth
- Regulation of Appetite and Obesity
- Aquaculture disease management and microbiota
- Protein Hydrolysis and Bioactive Peptides
- Adipose Tissue and Metabolism
- Enzyme Production and Characterization
- Growth Hormone and Insulin-like Growth Factors
- Insect Utilization and Effects
- Biofuel production and bioconversion
- Neuropeptides and Animal Physiology
- Hypothalamic control of reproductive hormones
- Plant-Microbe Interactions and Immunity
- Reproductive biology and impacts on aquatic species
- Studies on Chitinases and Chitosanases
- Microbial Metabolites in Food Biotechnology
- Adipokines, Inflammation, and Metabolic Diseases
- Physiological and biochemical adaptations
- Hormonal Regulation and Hypertension
- Antimicrobial Peptides and Activities
- Polysaccharides Composition and Applications
- Fungal Biology and Applications
- Autophagy in Disease and Therapy
- Apelin-related biomedical research
- Microencapsulation and Drying Processes
- Bone Tissue Engineering Materials
Sun Yat-sen University
2015-2025
Shandong University
2008-2024
Xichang University
2023-2024
Nanjing University of Information Science and Technology
2011-2024
Jiangxi University of Traditional Chinese Medicine
2024
Lanzhou Jiaotong University
2023
Shandong Marine Resource and Environment Research Institute
2023
Sichuan University
2020-2021
Chinese Academy of Fishery Sciences
2017-2020
Marine Biology Institute of Shandong Province
2020
Antibiosis is one of the widespread strategies used by Trichoderma spp. against plant fungal pathogens, mechanism which, however, remains poorly understood. Peptaibols are a large family antimicrobial peptides produced Our previous study showed that trichokonins, type peptaibol from pseudokoningii SMF2, exhibited antibiotic activities pathogens. In this study, we first demonstrated trichokonin VI (TK VI) induced extensive apoptotic programmed cell death in For deeper insight into involved...
Antimicrobial metabolites produced by Trichoderma koningii SMF2 exhibited antimicrobial activity against a range of Gram-positive bacterial and fungal phytopathogens. Purification these was achieved using combinations gel filtration high-performance liquid chromatography. Identified chromatography electrospray ionization tandem mass spectrometry, the active proved to be three known peptaibols: Trichokonin VI, VII VIII. The Trichokonins were stable remained biological over wide pH at every...
Abstract Background Hepatocellular carcinoma (HCC) is one of the most common cancers in world which highly chemoresistant to currently available chemotherapeutic agents. Thus, novel therapeutic targets are needed be sought for successful treatment HCC. Peptaibols, a family peptides synthesized non-ribosomally by Trichoderma species and other fungi, exhibit antibiotic activities against bacteria fungi. Few studies recently showed that peptaibols exerted cytotoxicity toward human lung...
Some tropical sea cucumbers of the family Holothuriidae can efficiently repel or even fatally ensnare predators by sacrificially ejecting a bioadhesive matrix termed Cuvierian organ (CO), so named French zoologist Georges Cuvier who first described it in 1831. Still, precise mechanisms for how adhesiveness genetically arose CO and perceive transduce danger signals expulsion during defense have remained unclear. Here, we report high-quality, chromosome-level genome assembly
Abstract Acetes chinensis is an underutilized shrimp species thriving in the Bo Hai Gulf of China. In a previous study, we had used protease from Bacillus sp. SM98011 to digest this kind and found that oligopeptide‐enriched hydrolysate possessed antioxidant activity high angiotensin I‐converting enzyme (ACE) inhibitory with IC 50 value 0.97 mg/ml. paper, by ultrafiltration, gel permeation chromatography reversed‐phase high‐performance liquid (RP‐HPLC), five peptides ACE were purified...
Saprotrophy on plant biomass is a recently developed nutrition strategy for Trichoderma. However, the physiology and evolution of this new still elusive. We report deep sequencing analysis genome Trichoderma longibrachiatum, an efficient cellulase producer. The 31.7-Mb genome, smallest among sequenced species, encodes fewer nutrition-related genes than saprotrophic T. reesei (Tr), including glycoside hydrolases nonribosomal peptide synthetase–polyketide synthase. Homology phylogenetic...
Many marine microorganisms synthesize exopolysaccharides (EPSs), and some of these EPSs have been reported to potential in different fields. However, the pharmaceutical potentials are rarely reported. The EPS secreted by Artic bacterium Polaribacter sp. SM1127 has good antioxidant activity, outstanding moisture-retention ability, considerable protective property on human dermal fibroblasts (HDFs) at low temperature. Here, effects skin wound healing frostbite injury prevention were studied....
Marine xylanases are rather less studied compared to terrestrial xylanases. In this study, a new xylanase gene, xynB, was cloned from the marine bacterium, Glaciecola mesophila KMM241, and expressed in Escherichia coli. xynB encodes multi-domain XynB of glycoside hydrolase (GH) family 8. The recombinant comprises an N-terminal domain (NTD) with unknown function catalytic domain, which is structurally novel among characterized GH has highest identity (38%) rXyn8 showed maximal activity at pH...
Alternative splicing is crucial for proteome diversity and functional complexity in higher organisms. However, the alternative landscape fungi still elusive.The transcriptome of filamentous fungus Trichoderma longibrachiatum was deep sequenced using Illumina Solexa technology. A total 14305 splice junctions were discovered. Analyses events revealed that number all (10034), intron retentions (IR, 9369), 5' sites (A5SS, 167), 3' (A3SS, 302) 7.3, 7.4, 5.1, 5.9-fold higher, respectively, than...
This study investigates the impact of two types anesthetics, tricaine methanesulfonate (MS-222) and eugenol, in gills juvenile Lateolabrax maculatus. Fish (Mean ± SD, 98.1 7.3 g) were randomly exposed to three treatments, MS-222 (50 mg/L), eugenol (10 or anesthetic-free water (control), each with five replicates. Gills sampled at 0, 1, 3, 6, 12, 24, 48 h after exposure above anesthetics for 20 min. both had significant immunomodulatory effects on gills. Physiological assays revealed that...