Da Huo

ORCID: 0000-0002-3534-1644
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About
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Research Areas
  • Aquatic Ecosystems and Phytoplankton Dynamics
  • Microbial Community Ecology and Physiology
  • Marine and coastal ecosystems
  • Echinoderm biology and ecology
  • Viral Infections and Immunology Research
  • Biocrusts and Microbial Ecology
  • Viral gastroenteritis research and epidemiology
  • SARS-CoV-2 and COVID-19 Research
  • Animal Disease Management and Epidemiology
  • Graphene and Nanomaterials Applications
  • Marine Bivalve and Aquaculture Studies
  • Natural Language Processing Techniques
  • Vibrio bacteria research studies
  • Respiratory viral infections research
  • Electrospun Nanofibers in Biomedical Applications
  • Topic Modeling
  • Circular RNAs in diseases
  • Tissue Engineering and Regenerative Medicine
  • Aquaculture disease management and microbiota
  • Species Distribution and Climate Change
  • Crystallization and Solubility Studies
  • Tea Polyphenols and Effects
  • Plant and Fungal Species Descriptions
  • Wildlife Ecology and Conservation
  • Aquatic life and conservation

Nanjing Medical University
2024-2025

University of Chinese Academy of Sciences
2017-2024

Institute of Hydrobiology
2018-2024

Chinese Academy of Sciences
2017-2024

Institute of Oceanology
2017-2024

Qingdao National Laboratory for Marine Science and Technology
2017-2024

Hebei University
2023-2024

Institute of Hydrobiology, Biology Centre, Academy of Sciences of the Czech Republic
2024

Guizhou Academy of Sciences
2024

Marine Biology Institute of Shandong Province
2023

Apart from sharing common ancestry with chordates, sea cucumbers exhibit a unique morphology and exceptional regenerative capacity. Here we present the complete genome sequence of an economically important cucumber, A. japonicus, generated using Illumina PacBio platforms, to achieve assembly approximately 805 Mb (contig N50 190 Kb scaffold 486 Kb), 30,350 protein-coding genes high continuity. We used this resource explore key genetic mechanisms behind biological characters cucumbers....

10.1371/journal.pbio.2003790 article EN cc-by PLoS Biology 2017-10-12

The lemon essential oil (LEO), extracted from the fruit of lemon, has been used to treat multiple pathological diseases, such as diabetes, inflammation, cardiovascular depression and hepatobiliary dysfunction.The study was designed effects LEO on cognitive dysfunction induced by Alzheimer's disease (AD).We APP/PS1 double transgene (APP/PS1) AD mice in experiment; these exhibit significant deficits synaptic density hippocampal-dependent spatial related memory.The learning memory were examined...

10.18632/aging.103179 article EN cc-by Aging 2020-05-11

Abstract Background Chloroplast genome resources can provide useful information for the evolution of plant species. Tea ( Camellia sinensis ) is among most economically valuable member . Here, we determined chloroplast first natural triploid Chinary type tea (‘Wuyi narcissus’ cultivar var. , CWN and conducted comparison with diploid CSS two types Assamica teas assamica : Chinese tea, CSA Indian CIA ). Further, evolutionary mechanism relationships species based on were discussed. Results...

10.1186/s12864-021-07427-2 article EN cc-by BMC Genomics 2021-02-26

Some tropical sea cucumbers of the family Holothuriidae can efficiently repel or even fatally ensnare predators by sacrificially ejecting a bioadhesive matrix termed Cuvierian organ (CO), so named French zoologist Georges Cuvier who first described it in 1831. Still, precise mechanisms for how adhesiveness genetically arose CO and perceive transduce danger signals expulsion during defense have remained unclear. Here, we report high-quality, chromosome-level genome assembly

10.1073/pnas.2213512120 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2023-04-10

Dissolved organic matter (DOM) acts as a chemical intermediary between terrestrial and lacustrine ecosystems significantly affects the structure function of lakes. The trophic state lakes, driven by input phytoplankton biomass, alters optical properties DOM. From November 2018 to July 2019, we collected 119 water samples from Erhai watershed analyzed them using UV–Vis EEM-PARAFAC study DOM in relation conditions. Our result indicated that tyrosine-like protein (C1), tryptophan-like (C2),...

10.1016/j.ecoinf.2024.102703 article EN cc-by Ecological Informatics 2024-06-29

Abstract This paper explores typical business models for rural clean energy systems, analyzing the current state of production and consumption. Based on specific characteristics supply demand, three are proposed. The also delves into roles responsibilities market participants, designing model frameworks suited various scenarios. aim is to promote development commercialization through innovative models, supporting implementation revitalization strategy.

10.1088/1742-6596/2932/1/012019 article EN Journal of Physics Conference Series 2025-01-01

The purpose of this study was to investigate the disclosure incidence cancer diagnosis patients before chemotherapy, survey attitudes and their families related influencing factors toward diagnosis, compare anxiety depression levels between non-disclosure patients.A prospective cohort conducted at a tertiary hospital in China. A consecutive series who had been diagnosed with malignancy by pathology family member were included our from March 2017 December 2017. Patients' situation,...

10.2147/cmar.s166437 article EN cc-by-nc Cancer Management and Research 2018-07-01

Polyphasic taxonomic studies have been extensively carried out in cyanobacteria, resulting the description of numerous cyanobacterial genera and species. The present study described a new genus Compactonostoc gen. nov. based on combination morphological, genetic, ecological evidence. was collected from wet rocky wall Shennongjia Forestry District, China. Colonies strain were usually uniseriate or only short segments biseriate when young, filaments became densely entangled to form macroscopic...

10.1080/00318884.2018.1541270 article EN Phycologia 2019-03-04

Host-intestine microbiota interactions have been widely studied in aquatic animals, but these the intestine regeneration process of sea cucumber Apostichopus japonicus rarely investigated. To understand how impacts developing intestinal microbiome composition and function, we performed a case study to characterize microbial functional genes A. during stages. High-throughput 16S rRNA gene sequencing revealed significantly different compositions The phylogenetic diversity changed early stage...

10.3389/fmicb.2019.01165 article EN cc-by Frontiers in Microbiology 2019-06-04

Abstract The transplant of small‐diameter tissue engineering blood vessels (small‐diameter TEBVs) (<6 mm) in vascular replacement therapy often fails because early onset thrombosis and long‐standing chronic inflammation. specific inflammation state involved TEBVs transplants remains unclear, whether promoting resolution would be useful for need study. neural protuberant orientation factor 1 (Netrin‐1) is found present endothelial cells natural has anti‐inflammatory effects. This work...

10.1002/advs.201700278 article EN cc-by Advanced Science 2017-09-28

Thrombosis is one of the biggest obstacles in clinical application small-diameter tissue-engineered blood vessels (TEBVs). The implantation an unmodified TEBV will lead to platelet aggregation and further activation coagulation cascade, which high concentration adenosine diphosphate (ADP) that released by platelets plays important role. Inspired phenomenon endothelial cells continuously generate endogenous antiplatelet substances via enzymatic reactions, we designed a reduced graphene oxide...

10.1021/acsnano.7b04836 article EN ACS Nano 2017-10-16

Abstract The potential of biodiversity loss to impair the delivery ecosystem services has motived ecologists better understand relationship between and functioning. Although increasing evidence underlines collective contribution different components on simultaneous performance multiple functions (multifunctionality), we know little about trade‐offs individual diversity effects extent which they determine multifunctionality differentially. Here, at a subcontinental scale 62 dryland sites,...

10.1111/mec.15424 article EN cc-by-nc Molecular Ecology 2020-04-01

Abstract Small‐diameter (<6 mm) tissue–engineered blood vessels (TEBVs) have a low patency rate due to chronic inflammation mediated intimal hyperplasia. Functional coating with drug release is promising solution, but preventing the released from being rushed away by flow remains great challenge. A single‐walled carboxylic acid functionalized carbon nanotube (C‐SWCNT) used build an irregular mesh for TEBV coating. However, interaction between and cells still insufficient flow. Thus,...

10.1002/adhm.201800026 article EN Advanced Healthcare Materials 2018-04-10

Fopius arisanus is a solitary endoparasitoid that parasitizes variety of tephritid species. Native to the Indo-Australian region, it currently exploited worldwide as biological control agent due its exceptional efficiency in reducing pest populations. The any program affected by host location ability parasitoids. present study used Y-tube olfactometer test behavioural responses female F. four fruit species which had undergone different types damages: undamaged, damaged through Bactrocera...

10.3390/insects11040231 article EN cc-by Insects 2020-04-07

Abstract Aim Microbial diversity is one of the most important factors for maintaining performance multiple functions in soils (multifunctionality). However, existing studies typically consider taxonomic richness or Shannon entire community. We know little about connection network and phylogenetic facets their collective impact on multifunctionality. In this study, linkages effects within functional groups were disentangled drylands. Location The central Tibetan Plateau. Time period Present....

10.1111/geb.13295 article EN Global Ecology and Biogeography 2021-04-16

Acute myocardial infarction (AMI) is the death of cardiomyocytes caused by a lack energy due to ischemia. Nutrients supplied blood are main source cellular for cardiomyocytes. Sodium butyrate (NaB), gastrointestinal nutrient, short‐chain fatty acid (butyric acid) that may act as an in AMI therapy. Poly(lactic‐co‐glycolic acid)‐Poly ( N ‐isopropylacrylamide) microspheres loaded with NaB (PP‐N) synthesized prolong release and injected into ischemic zones Sprague–Dawley rat model. Here, this...

10.1002/advs.201600254 article EN cc-by Advanced Science 2016-10-24

Abstract Rupture‐prone atherosclerotic plaque is the cause of high mortality and morbidity rates that accompany atherosclerosis‐associated diseases. MicroRNAs can regulate expression a variety inflammation‐related genes in macrophages. There are currently no definitive methods for delivering microRNAs into interior plaque. Monocytes typically possess pathological feature allows them to be recruited resulting rupture‐prone; however, whether monocytes modified gene carriers remains unclear. In...

10.1002/adhm.201900386 article EN Advanced Healthcare Materials 2019-06-06

This paper proposes a method to disentangle and quantify interactions among words that are encoded inside DNN for natural language processing. We construct tree encode salient extracted by the DNN. Six metrics proposed analyze properties of between constituents in sentence. The interaction is defined based on Shapley values words, which considered as an unbiased estimation word contributions network prediction. Our used BERT, ELMo, LSTM, CNN, Transformer networks. Experimental results have...

10.1609/aaai.v35i16.17685 article EN Proceedings of the AAAI Conference on Artificial Intelligence 2021-05-18

Abstract Coxsackievirus A16 (CV‐A16) is a significant pathogen responsible for causing hand foot and mouth disease (HFMD) herpangina (HA). This study aimed to investigate the recent evolution spread of CV‐A16 by monitoring HFMD HA cases in 29 hospitals across 16 districts Beijing from 2019 2021. The first five each month hospital were included study. Real‐time reverse transcription polymerase chain reaction was used identify CV‐A16, CV‐A6, EV‐A71. From district, two four positive samples...

10.1002/jmv.28991 article EN Journal of Medical Virology 2023-07-28

Microorganisms are crucial components of the aquatic ecosystem due to their immense diversity and abundance. They vital in sustaining ecological services, especially maintaining essential biogeochemical cycles. Recent years have seen a substantial increase surplus nitrogenous pollutants ecosystems heightened occurrence anthropogenic activities. Elevated levels free ammonia (FA, NH

10.1128/spectrum.01051-24 article EN cc-by Microbiology Spectrum 2024-07-26
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