Asad M. Lak

ORCID: 0000-0003-1683-9997
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About
Contact & Profiles
Research Areas
  • Spine and Intervertebral Disc Pathology
  • Spinal Fractures and Fixation Techniques
  • Scoliosis diagnosis and treatment
  • Brain Metastases and Treatment
  • Meningioma and schwannoma management
  • Cervical and Thoracic Myelopathy
  • Vascular Malformations Diagnosis and Treatment
  • Pelvic and Acetabular Injuries
  • Intracranial Aneurysms: Treatment and Complications
  • Management of metastatic bone disease
  • Glioma Diagnosis and Treatment
  • Medical Imaging and Analysis
  • Lung Cancer Research Studies
  • Neuroscience and Neural Engineering
  • Sarcoma Diagnosis and Treatment
  • Advanced MRI Techniques and Applications
  • Neurofibromatosis and Schwannoma Cases
  • Neurological disorders and treatments
  • Photoacoustic and Ultrasonic Imaging
  • Cancer Immunotherapy and Biomarkers
  • Ultrasound in Clinical Applications
  • Spinal Hematomas and Complications
  • Ultrasound and Hyperthermia Applications
  • Cerebrospinal fluid and hydrocephalus
  • Musculoskeletal pain and rehabilitation

Brigham and Women's Hospital
2019-2023

Harvard University
2019-2023

University of Iowa
2023

Leiden University Medical Center
2021

Oxford University Press (United Kingdom)
2020

MRI-guided focused ultrasound thalamotomy has been shown to be an effective treatment for medication refractory essential tremor. Here, we report a clinical-radiological analysis of 123 cases thalamotomy, and explore the relationships between parameters, lesion characteristics outcomes. All patients undergoing by single surgeon were included. The procedure was performed as previously described, followed up 1 year. MRI 24 h post-treatment, locations volumes calculated. We retrospectively...

10.1093/brain/awab176 article EN Brain 2021-09-14

MRgFUS thalamotomy has gained popularity as an FDA approved, non-invasive treatment for patients with Essential Tremor and tremor predominant Parkinson's Disease. We present our initial clinical experience 160 consecutive cases of describe the outcomes long term follow-up.A retrospective chart review all who underwent at institution was performed. CRST Part A scores were obtained pre-operatively each follow-up visit along assessment side effects (SE). All had a post-operative MRI within 24 h...

10.3389/fneur.2022.743649 article EN cc-by Frontiers in Neurology 2022-02-18

Background Patients who undergo surgery for cervical radiculopathy are at risk developing adjacent segment disease (ASD). Identifying patients will develop ASD remains challenging clinicians. Purpose To and validate a deep learning algorithm capable of predicting by using only preoperative MRI in undergoing single-level anterior diskectomy fusion (ACDF). Materials Methods In this Health Insurance Portability Accountability Act-compliant study, retrospective chart review was performed 1244...

10.1148/radiol.2021204731 article EN Radiology 2021-09-21

Metastatic spinal cord compression (MSCC) imposes significant impairment on patient quality of life and often requires immediate surgical intervention. In this study the authors sought to estimate impact intervention in form mean quality-adjusted years (QALY) gained identify factors associated with positive outcomes.

10.3171/2020.1.spine191326 article EN Journal of Neurosurgery Spine 2020-04-03

The aim of the study was to investigate associations HG gene polymorphism on chicken growth and body composition traits in Arian broilers. Blood samples randomly collected before slaughter from four different commercial broiler lines (A, B, C D; 400 samples) at 6 weeks age. Genomic DNA extracted a fragment 776 bp size amplified using PCR-RFLP method. To determine restriction site intron 1 GH animals, MspI endonuclease resultant digested products were run 2% agarose gel studied. Birds...

10.12692/ijb/3.12.216-220 article EN International Journal of Biosciences (IJB) 2013-12-18

Adult cervical deformity (ACD) is a debilitating spinal condition that causes significant pain, neurologic dysfunction, and functional impairment. Surgery often performed to correct alignment, but the optimal amount of correction required improve patient-reported outcomes (PROs) are not yet well-defined.A review literature was Fisher z-transformation (Zr) used pool correlation coefficients between alignment parameters PROs. The strength defined according following: poor (0 < r ≤ 0.3), fair...

10.14245/ns.2040656.328 article EN cc-by-nc Neurospine 2021-05-18

Study Design. Retrospective cohort study. Objective. The primary objective of our study was to evaluate the surgical outcomes and complications minimally invasive surgery (MIS) versus open in management intermediate high grade spondylolisthesis, secondarily compare following MIS in-situ fusion reduction subgroups. Summary Background Data. High-grade spondylolisthesis is a relatively rare spine pathology with unknown prevalence. optimal long-term prognosis high-grade remain controversial....

10.1097/brs.0000000000003573 article EN Spine 2020-05-21

Venous thromboembolism (VTE), encompassing deep venous thrombosis (DVT) and pulmonary embolism (PE), causes postoperative morbidity mortality in neurosurgical patients. The use of pharmacological prophylaxis for DVT prevention the immediate period carries increased risk intracranial hemorrhage, especially after skull base surgeries.To investigate impact routine Doppler ultrasound monitoring tiered management VTE surgery.We retrospectively analyzed a large cohort consecutive adult patients...

10.1227/neu.0000000000001936 article EN Neurosurgery 2022-04-05

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10.1001/jamaneurol.2020.1078 article EN JAMA Neurology 2020-05-18

INTRODUCTION: High-grade spondylolisthesis is a relatively uncommon condition. The optimal surgical approach for management remains debatable. Although in-situ fusion preferred due to its lower risk of neural injury, it does not correct spinal alignment. In contrast, reduction corrects the deformity and provides high rate fusion, but has potential rates injury. We herein report our experience outcomes following minimally invasive versus open intermediate- high-grade spondylolisthesis....

10.1093/neuros/nyz310_820 article EN Neurosurgery 2019-08-20
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