- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Clinical Nutrition and Gastroenterology
- Liver Disease Diagnosis and Treatment
- Renal Transplantation Outcomes and Treatments
- Congenital Anomalies and Fetal Surgery
- Organ and Tissue Transplantation Research
- Organ Donation and Transplantation
- Aortic aneurysm repair treatments
- Liver physiology and pathology
- Cytomegalovirus and herpesvirus research
- Hepatitis C virus research
- Metabolism and Genetic Disorders
- Xenotransplantation and immune response
- Drug-Induced Hepatotoxicity and Protection
- Elasticity and Material Modeling
- Grief, Bereavement, and Mental Health
- Aortic Disease and Treatment Approaches
- Liver Diseases and Immunity
- Immune Cell Function and Interaction
- Pediatric Hepatobiliary Diseases and Treatments
- Transplantation: Methods and Outcomes
- Diabetes and associated disorders
- Parvovirus B19 Infection Studies
- Signaling Pathways in Disease
Weill Cornell Medical College in Qatar
2010-2020
Cornell University
2013-2014
Hamad Medical Corporation
2010
Texas A&M University at Qatar
2010
Carnegie Mellon University Qatar
2010
Abilene Christian University
2010
"Dunarea de Jos" University of Galati
2008
INTEGRIS Baptist Medical Center
1995-2006
Southern Illinois University Carbondale
2005
University of Oklahoma Health Sciences Center
2005
Epstein-Barr virus (EBV) has been associated with nasopharyngeal carcinoma, some lymphomas, and lymphoproliferative disease after organ transplantation. Many tumors that occur transplantation are clonal, a property classifies them as neoplastic. Clonality can be determined by analysis of the extrachromosomal circular DNA episomes produced EBV infection.We describe three young children in whom smooth-muscle developed 18 months to 5 1/2 years liver immunosuppression. We examined microscopy...
Under FK 506-based immunosuppression, the entire cadaver small bowel except for a few proximal and distal centimeters was translated to 17 randomly matched patients, of whom two had antigraft cytotoxic antibodies (positive cross-match). Eight patients received intestine only, eight in continuity with liver, one full multivisceral graft that included stomach, pancreas. One liver-intestine recipient died after an intestinal anastomotic leak, sepsis, graft-versus-host disease. The other 16 are...
We retrospectively reviewed parainfluenza and influenza virus infections that occurred in pediatric organ transplant recipients at our hospital from January 1985 through September of 1992. Cultures respiratory specimens revealed 45 42 (32 cases 13 infection). The following organs were transplanted: liver (28 patients), small bowel with without (4), heart (3), lung (5), kidney (2). Clinical presentations the patients outcomes similar regardless type isolated or transplanted. There 20 which...
Under FK506-based immunosuppression, 16 cadaveric small bowel transplantations were performed in 15 recipients with (n=5) or without (n=11) the large bowel. Twelve (80%) patients are alive after 1.5 to 19 months, 11 bearing their grafts, of which 4 include colon. The actuarial one-year patient and graft survivals 87.5% 65.9%, respectively. Five grafts lost acute (n=4) chronic (n=l) rejection, 3 these subsequently died 376, 440, 776 days total survival. Six developed severe CMV infection that...
To identify and assess the level of knowledge attitudes health care professionals (HCP) in Qatar toward organ donation transplantation, this cross-sectional study was carried out from October 2007 to February 2008 Accident Emergency Departments Intensive Care Units hospitals Hamad Medical Corporation (HMC). A representative sample 585 HCP working HMC approached 418 staff gave consent participate (71.5%). 36.8% were physicians, 48.6% nurses 14.6% Service (EMS) technicians. Of surveyed HCP,...
Noninvasive tests to differentiate the basis for acute dysfunction of kidney allograft are preferable invasive biopsies. We measured absolute levels 26 prespecified mRNAs in urine samples collected from graft recipients at time for-cause biopsy and investigated whether differential diagnosis is feasible using urinary cell mRNA profiles. profiled 52 patients with specimens indicating rejection (26 T cell–mediated antibody-mediated rejection) 32 tubular injury without rejection. A stepwise...
Under FK506-based immunosuppression, 13 abdominal multivisceral transplantations were performed in 6 children and 7 adults. Of the recipients, (53.8%) are alive well with functioning grafts after 9 to 31 months. Six recipients died: three from PTLD, one rejection, sepsis, respiratory failure. In addition postoperative complications occurring more than isolated cases included PTLD (n = 6), abscess formation 5), pancreatitis 3), ampullary dysfunction 2). addition, infection by enteric...
Evidence of recent parvovirus virus infection (as determined by the presence a positive IgM antibody titer) without other identified causes anemia was found in 5 26 pediatric solid-organ transplant recipients evaluated for moderate-to-severe between June 1990 and July 1991. Anemia tended to be chronic (median duration at time diagnosis 12 weeks) associated with normal red blood cell indices absence reticulocytes. The median age children presentation due 1.8 years 8 months after...
Total plasma exchange (TPE) corrects coagulopathy in patients with liver disease and removes hepatotoxins/cytokines. This improvement is transient but can be used as a bridge until an organ identified for transplantation (LTx) or the itself regenerates. Our aim was to retrospectively assess efficacy of TPE fulminant hepatic failure (FHF) its impact on function tests. Between 1995-2001, 39 FHF who had undergone were reviewed. defined according O'Grady criteria based duration encephalopathy...
A retrospective survey of nosocomial rotavirus infection in pediatric liver transplant recipients was performed. Immunocompetent children with infections served as controls. Co‐pathogens were not identified. total 12 cases and controls could be evaluated. New onset vomiting occurred 7/8 6/11 lasting an average 2.8 days per case 0.8 control (p<.05). fever (>38°C) noted 8/12 9/12 occult blood 7/11 1/12 (p<.01). concomitant rise fall transaminases 5/12 recipients. Eleven the maintained...