- Protease and Inhibitor Mechanisms
- Cell Adhesion Molecules Research
- Heavy Metal Exposure and Toxicity
- Neural and Behavioral Psychology Studies
- Environmental Toxicology and Ecotoxicology
- Microplastics and Plastic Pollution
- Circular RNAs in diseases
- Muscle activation and electromyography studies
- MicroRNA in disease regulation
- Aortic Disease and Treatment Approaches
- Epigenetics and DNA Methylation
- Multi-Criteria Decision Making
- Peptidase Inhibition and Analysis
- Occupational exposure and asthma
- Signaling Pathways in Disease
- Immunotherapy and Immune Responses
- Cancer-related molecular mechanisms research
- Platelet Disorders and Treatments
- Nutrition and Health in Aging
- Advanced Technologies in Various Fields
- Cellular Mechanics and Interactions
Anhui Medical University
2006-2022
Chengdu Military General Hospital
2018
University of California, San Francisco
2003-2004
We have previously shown that the integrin β6 is neo-expressed in invasive oral squamous cell carcinoma (SCC) and correlated with tumor progression. However, mechanism by which promotes progression not well understood. The purpose of present study was to determine whether signaling activates Fyn thus analyzed complex investigated function these molecules SCC cells. found that, upon ligation fibronectin, complexed activated it. activation recruited focal adhesion kinase this complex. This...
We explored the relationship between metals exposure and nervous impairment in welders. The of 82 welders 51 operators were evaluated for blood Pb, Cd Mn by atomic absorption spectrometry, system was with neurobehavioral core test battery electromyography. Pb (geometric mean: 117.31 mug/L; range: 0.5-327.6 mug/L) 3.54 0.2-12.5 significantly higher than those operators. Welders had prevalence symptoms worse standard scores 8 items such as depression-dejection Significant difference...
MicroRNA-126 (miR-126) has previously been reported to be downregulated in various types of cancer; however, at present, there are no studies miR‑126 human thyroid cancer. The present study aimed determine the expression and effects on levels were detected cancer tissues, matched normal adjacent tissues cell lines using quantitative polymerase chain reaction. In addition, post‑transfection cells with mimics, proliferation, migration invasion assays, western blot analysis luciferase assays...
The demethylation potential of environmental pollutants is possibly an innate part their comprehensive health risk. This paper develops a novel method called TDQ to quantify the epigenetic toxicity, termed 5-AZA-CdR toxic equivalency, aquatic samples from heavily polluted Bohai Bay using Hep G2 cell lines transiently transfected with pEGFP-C3 plasmid containing methylated promoter EGFP reporter gene inserted artificially in vitro. If sample extract has strong total promoter, its methylation...
Malnutrition and metabolic disorders are common problems faced by patients with Stanford type A aortic dissection after surgery. Some have dietary such as malnutrition, unbalanced diet, poor eating habits before Therefore, the nutritional management of early heart health can improve support for perioperative recovery, to pertinence. active surgery will help change malnutrition metabolism is great significance postoperative recovery quality life. This paper aimed at studying mode cardiac...