A5088200195- Mercury impact and mitigation studies
- Toxic Organic Pollutants Impact
- Heavy Metal Exposure and Toxicity
- Carcinogens and Genotoxicity Assessment
- DNA Repair Mechanisms
- Air Quality and Health Impacts
- Effects and risks of endocrine disrupting chemicals
- Per- and polyfluoroalkyl substances research
- Genetically Modified Organisms Research
- Drug Transport and Resistance Mechanisms
- GABA and Rice Research
- Chemical Reactions and Isotopes
- Gallbladder and Bile Duct Disorders
- Foreign Body Medical Cases
- Congenital Anomalies and Fetal Surgery
- Marine animal studies overview
- Selenium in Biological Systems
- Pediatric Hepatobiliary Diseases and Treatments
- CAR-T cell therapy research
- Aluminum toxicity and tolerance in plants and animals
- Autopsy Techniques and Outcomes
- Education and Learning Interventions
- Occupational and environmental lung diseases
- Identification and Quantification in Food
- Climate Change, Adaptation, Migration
National Institute for Minamata Disease
2005-2022
Akita University
1984-2003
Institute for Environmental Sciences
2003
Fukushima Medical University
2003
Konan University
1978
To understand the current Japanese hair mercury levels, we planned a survey of among general populations different regions in Japan. The present paper, as first report survey, summarized results obtained five districts, Minamata, Kumamoto, Tottori, Wakayama and Chiba. Hair samples were collected at beauty salons, barbershops primary schools each district with questionnaires on age, sex, amount species fish usually consumed, hair-dyed artificial waving "permanent wave." total levels 3686...
Possible induction of lacZ mutation was examined in the liver and testis Muta Mouse following administration carcinogenic halogenated compounds, namely 1,2-dichloroethane (DCE), 1,2-dibromoethane (DBE), carbon tetrachloride, or 1,2-dibromo-3-chloropropane (DBCP). Slight increases were observed on mutant frequency DNA isolated from mice 14 days after treatment with DBCP at 40 mg/kg DBE 60 but not liver. Further investigation necessary to confirm by these chemicals including experiments longer...
Congenital biliary dilatation is frequently complicated by tract cancer, and anomalous junction of the pancreaticobiliary ductal system, a major factor constituting pathology this disease, considered to be important as background for carcinogenesis in tract. To clarify mechanism under circumstance junction, we evaluated mutagenicity contents patients with congenital analyzed nuclear atypia epithelium fluorocytometry. A test using Bacillus subtilis showed positive results 6 12 patients. Since...
A novel acriflavine-sensitive mutant was isolated. The mutation referred to as acrB1 and demonstrated be located at min 82.
Secular Trends and Geographical Variations in the Dietary Intake of Polybrominated Diphenyl Ethers (PBDEs) Using Archived Samples from Early 1980s Mid 1990s Japan: Yasuhiko Wada, et al. Hyogo College Medicine —A retrospective exposure assessment among general population for polybrominated diphenyl ethers was conducted using dietary surveys. We analyzed samples food duplicate portions collected early (1980 survey: N=40) mid (1995 N=39) female subjects (5 participants each 8 sites per survey...
The concentration of methylmercury (MeHg) in human hair is an excellent marker for its exposure, since a portion MeHg taken up from the blood circulation to protein dose-dependent manner. However, small mercury found inorganic form, though mechanism occurrence not well established. Here, we examined uptake rat. Male Wistar rats were exposed (1 microg Hg/ml) or HgCl(2) (20 84 days through drinking water. hair, grown 49 days, was collected MeHg-exposed rats, and samples showed 54.5 microg/g...
Exposure to polychlorinated biphenyls (PCBs) is considered have culminated between 1950 and 1970 in Japan, exposure through diet, the major route, has decreased significantly over last 10 years. The primary goal of present study was investigate long-term trends congener profiles serum dietary levels PCBs using historical samples. Using banked samples collected 1980, 1995, 2003 surveys, we determined daily intakes concentrations 13 PCB congeners (#74, #99, #118, #138, #146, #153, #156, #163,...