A5087081534- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Nutrition, Health and Food Behavior
- Per- and polyfluoroalkyl substances research
- Consumer Attitudes and Food Labeling
- Toxic Organic Pollutants Impact
- Sodium Intake and Health
- Diet and metabolism studies
- Nutrition and Health in Aging
- Air Quality and Health Impacts
- Health disparities and outcomes
- Chemical Analysis and Environmental Impact
- Effects and risks of endocrine disrupting chemicals
- Gestational Diabetes Research and Management
- Gut microbiota and health
- Birth, Development, and Health
- Endometrial and Cervical Cancer Treatments
- Esophageal and GI Pathology
- Maternal Mental Health During Pregnancy and Postpartum
- Colorectal Cancer Screening and Detection
- Frailty in Older Adults
- Food Security and Health in Diverse Populations
- Fatty Acid Research and Health
- Carcinogens and Genotoxicity Assessment
- Gastric Cancer Management and Outcomes
Hokkaido University
2015-2025
The Health Care Science Institute
2023-2025
National Institute of Biomedical Innovation, Health and Nutrition
2018-2024
National Institute of Infectious Diseases
2018-2023
National Institute of Nutrition
2023
Hokkaido Institute of Public Health
2011-2022
New York University Press
2021
Cambridge University Press
2021
Osaka City University
2021
Chiba University
2021
Fatty acids (FAs) are essential for fetal growth. Exposure to perfluorinated chemicals (PFCs) may disrupt FA homeostasis, but there no epidemiological data regarding associations of PFCs and concentrations.We estimated between perfluorooctane sulfonate (PFOS)/perfluorooctanoate (PFOA) concentrations maternal levels FAs triglyceride (TG) birth size the offspring.We analyzed 306 mother-child pairs in this cohort 2002 2005 Japan. The prenatal PFOS PFOA were measured serum samples by liquid...
Sleep is essential for our health. Short sleep known to increase disease risks via imbalance of intestinal microbiota, dysbiosis. However, mechanisms by which short induces dysbiosis remain unknown. Small Paneth cell regulates the microbiota secreting antimicrobial peptides including α-defensin, human defensin 5 (HD5). Disruption circadian rhythm mediating sleep-wake cycle failure. We aim clarify effects on HD5 secretion and microbiota. Fecal samples self-reported time were obtained from 35...
Perfluoroalkyl substances (PFAS) are persistent bio-accumulative chemicals that impact the health of pregnant women and their children. PFAS derive from environmental consumer products, which depend on human lifestyle, socioeconomic characteristics, time variation. Here, we aimed to explore temporal trends in characteristics related maternal concentration. Our study is part Hokkaido Study Environment Children’s Health, large-scale cohort recruited between 2003 2011. Blood samples were...
Per- and polyfluoroalkyl substances (PFAS) are widely used bio-accumulative chemicals in many industrial household products. Experimental studies reported that exposure to PFAS results immunotoxicity. We have previously prenatal decreased the risk of allergies, while it increased infectious diseases at ages 2 4 years. However, remains unclear whether adverse effects on allergies continue until a reliable age diagnosing allergies. This study aimed investigating prevalence children up 7, from...
Prenatal maternal exposure to perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) has been reportedly associated with decreased birth weight. Although a majority of epidemiological studies concerning perfluoroalkyl substances (PFAS) have focused on PFOS PFOA, PFAS longer carbon chains are scarce. In this study, we investigated whether prenatal 11 PFAS, in particular those chains, is fetal growth. The study included 1985 mother-infant pairs (inclusive preterm post-term...
Perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) have been widely used as industrial products, are persistent organic pollutants due to their chemical stability. Previous studies suggested that PFOS PFOA might disrupt thyroid hormone (TH) status. Although TH plays an important role in fetal growth during pregnancy, little attention has paid the relationships between maternal exposure perfluorocarbons statuses of mothers fetuses. We investigated effects low levels environmental...
Colorectal cancer is the third most common worldwide, and in Japan, it estimated that about 10% of men 8% women will be diagnosed with colorectal during their lifetime.We focused on 5864 participants (3699 2165 women) who had were registered BioBank Japan (BBJ) between April 2003 March 2008. Characteristics colon rectal patients calculated separately. Among enrolled BBJ within 90 days after diagnosis, we also 5-year cumulative relative survival rates, effect lifestyle factors all-cause...
Abstract Monitoring nutritional status of the population is essential in development and evaluation national or local health policies. In this study, we aimed to demonstrate analysis on trends dietary intake energy macronutrients, as well Na, Japanese using data series cross-sectional surveys – National Nutrition Survey (NNS) Health (NHNS) during period from 1995 2016. The NNS NHNS participants aged 20–79 years were included analysis. Dietary was estimated 1-d household-based record. trend...
Abstract Few studies have reported the association between Japanese diet as food score and mortality. This study aimed to investigate adherence associated with all-cause, CVD cancer A total of 58 767 (23 162 men 34 232 women) participants aged 40–79 years, who enrolled in Japan Collaborative Cohort Study 1988 1990, were included. The was derived from components seven groups (beans bean products, fresh fishes, vegetables, pickles, fungi, seaweeds fruits) based on FFQ. ranged 0 7, divided into...
Thyroid antibodies (TAs) are the most common cause of hypothyroidism during gestation. Although previous studies found that prenatal exposure to perfluoroalkyl substances (PFASs) disrupts thyroid hormones (THs) in humans, their effects on TAs perinatal period have not been investigated.To explore associations between eleven different PFASs from two groups (carboxylates and sulfonates) expression THs maternal cord blood while considering TA status.In a prospective birth cohort (the Hokkaido...
Abstract Background Consumption of home-prepared meals may lead to better nutritional intake. Few studies have examined the association between frequency consuming prepared away from home and inadequacy intake based on standards food group We therefore aimed investigate this issue among Japanese adults. Methods This study was a secondary analysis 2015 National Health Nutrition Survey in Japan, involving 921 men 1300 women aged 18–64 years, conducted as cross-sectional survey. The defined...
Several studies have evaluated associations between the characteristics of patients with esophageal and gastric cancer survival, but these remain unclear. We described distribution demographic lifestyle factors among in Japan, investigated their potential effects on survival. Between 2003 2007, 24- to 95-year-old Japanese were enrolled BioBank Japan Project. The analysis included 365 squamous cell carcinoma (ESCC) 1574 cancer. Hazard ratios (HRs) 95% confidence intervals (CIs) for mortality...