A5109758142- Animal Virus Infections Studies
- Herpesvirus Infections and Treatments
- Virus-based gene therapy research
- Lubricants and Their Additives
- Tribology and Wear Analysis
- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- Diamond and Carbon-based Materials Research
- interferon and immune responses
- Plant Virus Research Studies
- T-cell and Retrovirus Studies
- Liver Disease Diagnosis and Treatment
- Virology and Viral Diseases
- Diet, Metabolism, and Disease
- Diet and metabolism studies
- Advanced biosensing and bioanalysis techniques
- Molecular Sensors and Ion Detection
- RNA Interference and Gene Delivery
- Cancer-related molecular mechanisms research
- Viral Infections and Immunology Research
- Hepatitis Viruses Studies and Epidemiology
- Viral Infectious Diseases and Gene Expression in Insects
- Viral Infections and Vectors
- Luminescence and Fluorescent Materials
- Advanced Nanomaterials in Catalysis
Second Affiliated Hospital of Xi'an Jiaotong University
2021-2025
University of Alabama at Birmingham
2024-2025
Ocean University of China
2021-2025
Ruijin Hospital
2025
Shanghai Jiao Tong University
2025
Shanghai Institute of Hematology
2025
Dalian University of Technology
2025
Tianjin University of Science and Technology
2023-2024
Hebei Science and Technology Department
2023-2024
Shandong Agricultural University
2013-2024
Background Epithelial damage, repair and remodelling are critical features of chronic airway diseases including obstructive pulmonary disease (COPD). Interleukin (IL)-33 released from damaged epithelia causes inflammation via its receptor, serum stimulation-2 (ST2). Oxidation IL-33 to a non-ST2-binding form (IL-33 ox ) is thought limit activity. We investigated whether has functional activities that independent ST2 in the epithelium. Methods In vitro epithelial damage assays...
Leveraging the advantages of shape retention and atomic reconstruction during carbonizing crystalline precursors, we demonstrated an efficient strategy to manufacture boron–nitrogen codoped carbon nanosheets (B,N@PCNS) by virtue pyrolysis combining metal–organic framework (MOF) precursors B-dopants. Through regulation ratio between reactants, implemented ultrahigh-surface heteroatomic doping rate N at 10.44 atom % B 5.60 with homogeneous distribution, which significantly enhanced...
Abstract This study presents a nitrogen-doped microporous carbon nanospheres (N@MCNs) prepared by facile polymerization–carbonization process using low-cost styrene. The N element in situ introduces polystyrene (PS) via emulsion polymerization of styrene with cyanuric chloride as crosslinking agent, and then carbonization obtains N@MCNs. as-prepared possess the complete spherical structure adjustable nitrogen amount controlling relative proportion tetrachloromethane chloride. friction...
Purpose: Persistent Infections and inflammation are associated with impaired wound healing in diabetic patients. There is a pressing demand for innovative antimicrobial strategies to address infections arising from antibiotic-resistant bacteria. Polymer-modified gold nanoparticles (AuNPs) show broad-spectrum antibacterial properties significant biocompatibility. This study investigated the efficacy of hydrogel dressings conjugated chitosan-AuNPs model rats. Methods: Chitosan...
Herein, the novel core–shell organo-inorganic hybrid carbon nanospheres with encapsulated ultrafine bimetal nanocrystals were successfully prepared by a one-pot domino drive synthesis combined postcarbonization. The excellent properties of metals such as high strength and thermal conductivity are retained, poor dispersion metal in oil could be improved encapsulating organic–inorganic nanospheres. vanadium wolframium embedded nitrogen-doped (V/W@NCNs) manifested remarkable dispersity on...
The spike proteins of coronaviruses are capable binding to a wide range cellular targets, which contributes the broad species tropism coronaviruses. Previous reports have demonstrated that Middle East respiratory syndrome coronavirus (MERS-CoV) predominantly utilizes dipeptidyl peptidase 4 (DPP4) for cell entry. However, additional targets MERS-CoV protein may augment infection not been further explored. In current study, using virus overlay assay (VOPBA), we identified carcinoembryonic...
Herein, organic–inorganic hybrid sulfur-containing carbon nanospheres (SCNs) were successfully prepared by one-pot chemical oxidation polymerization of a thiophene monomer and then rigorous carbonization. On account the good structural strength organic phase derived from precursor polythiophene, as-prepared SCNs manifested remarkable oil-dispersing tribological properties as lubricant nanoadditives. Subsequently, friction mechanism was deduced; had capacity to take shape strong protective...
PHPMA-<italic>b</italic>-PBzMA diblock copolymer nano-assemblies were synthesized by ATRP dispersion polymerization and compared with those obtained RAFT polymerization.
An oral probiotic vaccine, pYG-KHV-ORF81/LR CIQ249, encapsulated by chitosan-alginate capsules as an delivery system was developed for koi carp against herpesvirus (KHV) infection. This vaccine can be protected from various digestive environments and maintain effectively high viability, showing a good tolerance to environments.
Abstract Atrial fibrillation (AF) is an increasingly prevalent arrhythmia with significant health and socioeconomic impact. The underlying mechanism of AF still not well understood. In this study, we sought to identify hub genes involved in AF, explored their functions mechanisms based on bioinformatics analysis. Five microarray datasets GEO were used the differentially expressed (DEGs) by Robust Rank Aggregation (RRA), screened out using protein–protein interaction (PPI) network. model was...
Zinc, which is the second most abundant trace element in human central nervous system, closely associated with Alzheimer's disease (AD). However, attempts to develop highly sensitive and selective sensing systems for Zn2+ brain have not been successful. Here, we used a one-step solvothermal method design prepare metal–organic framework (MOF) containing dual ligands, terephthalic acid (H2BDC) 2,2′:6′,2″-terpyridine (TPY), Eu3+ as metal node. This MOF denoted Eu-MOF/BDC-TPY. Adjustment of size...
Farnesyl protein transferase inhibitors (FTIs) were originally developed to inhibit oncogenic ras, however it is now clear that there are several other potential targets for this drug class. The FTI tipifarnib (ZARNESTRA, R115777) has recently demonstrated clinical responses in adults with refractory and relapsed acute leukemias. This study was conducted identify genetic markers pathways regulated by myeloid leukemia (AML).Tipifarnib-mediated gene expression changes 3 AML cell lines bone...
The aim of this study was to investigate possible causes the pervasiveness chicken infectious anemia virus (CIAV) infection in chickens recent years China. A total 14 batches live-virus vaccines were examined using PCR detect CIAV contamination, which only 2 samples (a Newcastle disease vaccine and a fowl pox vaccine) tested positive for CIAV. These then inoculated into 1-day-old specific-pathogen-free chickens. Serum collected from infected with PCR-positive vaccines, these CIAV-specific...
Bovine viral diarrhea caused by bovine virus (BVDV) is an important disease in cattle, resulting significant economic losses to the cattle industry worldwide. In order develop effective vaccine against BVDV infection, we constructed a dendritic cell (DC)-targeting oral probiotic (pPG-E2-DCpep/LC W56) using Lactobacillus casei as antigen delivery carrier express glycoprotein E2 fused with DC-targeting peptide, and immunogenicity of orally administered was evaluated mice model. Our results...