A5102483997- Gut microbiota and health
- Lung Cancer Treatments and Mutations
- Inflammatory Bowel Disease
- MicroRNA in disease regulation
- Lung Cancer Research Studies
- Autophagy in Disease and Therapy
- Circular RNAs in diseases
- Palliative Care and End-of-Life Issues
- Lung Cancer Diagnosis and Treatment
- Medical Research and Treatments
- Cancer survivorship and care
- Barrier Structure and Function Studies
- Family and Patient Care in Intensive Care Units
- Pancreatitis Pathology and Treatment
- Geological and Geochemical Analysis
- Cancer Immunotherapy and Biomarkers
- Smart Agriculture and AI
- Attention Deficit Hyperactivity Disorder
- Clostridium difficile and Clostridium perfringens research
- Remote Sensing in Agriculture
- High-pressure geophysics and materials
- Peripheral Neuropathies and Disorders
- Regional Development and Environment
- Educational Technology and Pedagogy
- Surgical site infection prevention
Zhejiang Chinese Medical University
2024-2025
China Agricultural University
2022-2025
Wuhan University
2019-2025
Renmin Hospital of Wuhan University
2019-2025
Wuhan Prevention and Treatment Center for Occupational Diseases
2025
Affiliated Hospital of Qingdao University
2019-2024
Qingdao University
2019-2024
Nanjing University
2023-2024
University of South China
2024
Lanzhou University
2024
Aims: We aimed to measure the abundance of Fusobacterium nucleatum (F. nucleatum) in colorectal cancer (CRC) tissues from patients and uncover function this bacterium tumor metastasis. Methods: collected metastatic non-metastatic CRC analyze F. abundance. Cells were incubated with or chloroquine (CQ) transfected CARD3-targeting siRNA; expression mRNAs proteins was then measured. cells stably shRNA-luc mixed intravenously injected into BALB/cJ mice. APCMin/+, CARD3-/-and CARD3wt C57BL mice...
Circular RNAs (circRNAs) belong to a new type of endogenous non-coding RNA and plays key role in carcinogenesis. Circ-ZKSCAN1 (hsa_circ_0001727) has been proven be tumor-dependent circRNA. However, its non-small cell lung cancer (NSCLC) underreported.The expression patterns circ-ZKSCAN1 were determined using qRT-PCR NSCLC samples lines. Cell proliferation was examined utilizing the CCK-8 assay. migration invasion evaluated Transwell The combination miR-330-5p cells analyzed by pull-down...
Abstract The Western diet, characterized by its high content of long-chain fatty acids (LCFAs), is widely recognized as a significant triggering factor for inflammatory bowel disease (IBD). While the link between high-fat diet and colitis has been observed, specific effects mechanisms remain incompletely understood. Our study provides evidence that rich in LCFAs can disrupt integrity intestinal barrier exacerbate experimental mice. Mechanistically, upregulate signal transducer activator...
Abstract Accumulating evidence links Fusobacterium nucleatum with ulcerative colitis (UC). The mechanism by which F. promotes intestinal inflammation in UC remains poorly defined. Here, we first examined the abundance and impact of on disease activity tissues. Next, isolated a strain from tissues explored whether aggravates inflammatory response vitro vivo . We also infection involves NF‐κB or IL‐17F signaling pathways. Our data showed that was enriched 51.78% correlated clinical course,...
There is a growing body of evidence which suggests that intestinal microbiota, especially Fusobacterium nucleatum ( F. ), are associated with immune disease such as ulcerative colitis (UC). The mechanism by promotes epithelial cell (IEC) death remained undefined. Here, we investigated the potential mechanisms about how aggravates IEC in UC. We first detected abundance UC tissues and analyzed its relationship clinical characteristics Next, explored whether vitro vivo . Furthermore, extracted...
Lung adenocarcinoma (LUAD), which is the most common subtype of non-small cell lung cancer, a leading course cancer-related mortality worldwide. Recently, circular RNA (CircRNAs) has become hot spot in cancer research because its important role tumorigenesis and development superior stability. This study aims to clarify circ-AASDH LUAD explore competitive endogenous mechanism.The circ-AASDH, miR-140-3p E2F transcription factor 7 (E2F7) mRNA expression levels were detected via qRT-PCR. CCK-8...
The exploration of functional films using sustainable cellulose-based materials to replace plastics has been much interest. In this work, two kinds lignin nanoparticles (LNPs) were mixed with cellulose nanofibrils (CNFs) for the fabrication composite biodegradable, flexible and ultraviolet blocking performances. LNPs isolated from p-toluenesulfonic acid hydrolysis was easily recondensed deposited on surface film, resulting in a more uneven surface; however, film consisting CNFs maleic...
Introduction Attention deficit hyperactivity disorder (ADHD) is one of the common neurodevelopmental disorders and widely prevalent worldwide. The primary symptoms ADHD include inattention, impulsivity, hyperactivity, which significantly impact cognitive, behavioral, emotional dimensions individuals. These often continue throughout adulthood and, along with associated complications, affect various domains such as personal health, academic achievement, social interactions. pathogenesis...
Computer vision technology is widely used in smart agriculture, primarily because of its non-invasive nature, which avoids causing damage to delicate crops. Nevertheless, the deployment computer algorithms on agricultural machinery with limited computing resources represents a significant challenge. Algorithm optimization aim achieving an equilibrium between accuracy and computational power pivotal research topic core focus our work. In this paper, we put forward lightweight hybrid network,...
Iron-based metal-organic frameworks (Fe-MOFs) are widely used for agricultural chemical delivery due to their high loading capacity, and they also have the potential provide essential iron plant growth. Therefore, hold significant promise applications. Evaluating biotoxicity of Fe-MOFs is crucial optimizing use in agriculture. In this study, we natural biomacromolecule carboxymethyl cellulose (CMC) encapsulate Fe-MOF NH2-MIL-101 (Fe) (MIL). Through hydroponic experiments, investigated...
Background Osteoporosis is a prevalent chronic result of diabetes. susceptibility raised by unstable blood glucose levels, oxidative stress, hormonal abnormalities, and other factors. Currently, there no systematic review addressing the risk factors osteoporosis in This study intends to systematically assess current related diabetic (DOP) provide suggestions for improvement therapy approaches. Methods analysis We will search five English literature databases (PubMed, Embase, Web Science,...
Megawite, a recently discovered perovskite-structured mineral with Ca(Ti0.07, Sn0.6, Zr0.33)O3, was identified in xenolith. Its end members, CaTiO3, CaSnO3, and CaZrO3, represent GdFeO3-type perovskites (A2+B4+O3), which have garnered significant attention for their structural physical properties. Among these, CaSnO3 stands out due to its exceptional optical electrical properties, supported by high chemical stability. Despite increasing applications, critical properties such as the elastic...
Introduction: The completeness of esophagogastroduodenoscopy (EGD) is a prerequisite for detecting lesions. This study aims to explore whether the quality complete examinations assisted by artificial intelligence (AI) would be comparable those conducted within guideline-recommended inspection time. Methods: Patients referred diagnostic, screening, or surveillance EGD were enrolled at Renmin Hospital Wuhan University. randomly assigned two groups in 1:1 ratio. In AI-assisted group,...
This study addresses the labor-intensive and safety-critical challenges of manual oyster processing by innovating an advanced robotic intelligent sorting system. Central to this system is integration a high-resolution vision module, dual operational controllers, collaborative AUBO-i3 robot, all harmonized through sophisticated Robot Operating System (ROS) framework. A specialized image dataset was curated augmented train robust You Only Look Once version 8 Oriented Bounding Box (YOLOv8-OBB)...
There is increasing evidence that members of the gut microbiota, especially Fusobacterium nucleatum ( F. ), are associated with Crohn’s disease (CD), but specific mechanism by which promotes CD development unclear. Here, we first examined abundance and its effects on activity explored whether aggravated intestinal inflammation promoted mucosal barrier damage in vitro vivo . Our data showed was enriched 41.21% tissues from patients correlated clinical course, activity, refractory behavior (P...
Background: As a type of non-coding RNA, circular RNAs (circRNAs) are considered to be functional molecules associated with human cancers. An increasing number circRNAs have been verified in malignant progression The circRNA, circFBXW7, has proven play an important role tumor proliferation and metastasis. However, whether circFBXW7 influences lung adenocarcinoma (LUAD) remains unclear.Methods: Quantitative real-time reverse transcriptase PCR (qRT-PCR) was used verify LUAD cell lines tissues....
This study investigated the efficacy of botanical-derived drug, PG2, a partially purified extract Astragalus membranaceus, as complementary and palliative medicine for managing cancer-related fatigue (CRF).Patients with advanced cancer moderate to severe CRF were randomized receive either PG2 or placebo (normal saline, NS) in first treatment cycle (four weeks) double-blind manner; thereafter, on next weeks), all patients received open-label PG2.PG2 significantly improved NS-primed group. In...
Introduction Type 2 diabetes mellitus (T2DM) is a frequent chronic condition among the elderly, which increasing their susceptibility to infection. Urinary tract infection (UTI) one of most prevalent infections older people with T2DM. However, association between geriatric T2DM and risk UTI has not been thoroughly researched still contentious. Consequently, this protocol describes systematic review pinpoint primary factors for elderly Our goal improve recommendations creation targeted...
Aims This study aimed to conduct a bibliometric analysis of the relevant literature on interaction between microbiota and immune in intestinal inflammatory diseases, show its current status, hotspots, development trends. Methods The related was acquired from Web Science Core Collection October 12, 2022. Co-occurrence cooperation relationship authors, institutions, countries, references, keywords were carried out through CiteSpace 6.1.R3 software Online Analysis platform Literature Metrology....