- Hematological disorders and diagnostics
- Hematopoietic Stem Cell Transplantation
- Acute Myeloid Leukemia Research
- Diet, Metabolism, and Disease
- Lymphoma Diagnosis and Treatment
- Bacterial biofilms and quorum sensing
- Antibiotic Resistance in Bacteria
- Mesenchymal stem cell research
- Circular RNAs in diseases
- Eicosanoids and Hypertension Pharmacology
- Cancer-related molecular mechanisms research
- Drug Transport and Resistance Mechanisms
- Cancer, Hypoxia, and Metabolism
- Immune Cell Function and Interaction
- Bacterial Identification and Susceptibility Testing
- MicroRNA in disease regulation
- Sarcoma Diagnosis and Treatment
- Digital Imaging for Blood Diseases
- Congenital Heart Disease Studies
- Neonatal Respiratory Health Research
- Immune cells in cancer
- Bone and Joint Diseases
- Cardiovascular Health and Risk Factors
- Cardiovascular Function and Risk Factors
- Virus-based gene therapy research
Children's Hospital of Chongqing Medical University
2025
China International Science and Technology Cooperation
2025
Chongqing Medical University
2025
Peking University
2024
Peking University Third Hospital
2024
Shanghai Jiao Tong University
2014-2023
Shanghai Institute of Hematology
2023
Shanghai Tenth People's Hospital
2022
Tongji University
2022
Fudan University
2021
Objective: To investigate the disease burden, clinical characteristics and independent risk factors affecting in-hospital outcomes of children with congenital heart (CHD) combined failure (HF) in China. Methods: (1) Descriptive study: based on global burden study 2021, available data under 15 years age CHD HF China from 1990 to 2021 were collected. The prevalence trends different subgroups (<1 year, 1-<2 years, 2-<5 5-<10 10-<15 years) analyzed, annual percentage change (EAPC) was estimated...
Bone marrow (BM) aspiration is largely used for relapse assessment in acute myeloid leukemia (AML). It remains unclear what roles that BM trephine biopsy plays on assessment.Bone sections during complete remission (CR) from 60 (AML) patients were retrospectively analyzed. Computer image processing technology was performed detection of the distance between precursors and endosteum, density also calculated under light microscopic image. Immunohistochemistry to identify immunophenotype...
A large proportion of liver cancer cases is caused by hepatitis B virus (HBV) infection. In recent years, an increasing number reports have indicated that circular RNAs (circRNAs) exert regulatory effects in development, whereas the role circRNAs HBV-positive requires further investigation. present study, abnormally expressed were identified cells through microarray analysis. total 1,493 differentially [absolute fold-change (FC) ≥2] detected, which 171 upregulated and 1,322 downregulated....
Abstract Background Patients with acute coronary syndrome (ACS) are still at high risk of recurring major adverse cardiovascular events (MACE). Disorders lipid metabolism play an important role in the pathogenesis and progression ACS. However, whether there components that can early warning on recurrence MACE patients ACS its potential mechanism is not yet known. Purpose To explore changes profile before recurrent patients, screen molecules related to MACE, their effects pathological...
This study retrospectively analyzed the genome characteristics of blaKPC-2 in multidrug-resistant Klebsiella pneumoniae collected from ICU a teaching hospital Shanghai, China.From February 2018 to December 2019, 36 strains were bronchoalveolar lavage fluid critically ill patients. The all isolates was obtained through Illumina sequence, and single nucleotide polymorphisms gene explore blaKPC-2's evolutionary characteristics. Different strains' genetic relationships homology studied by...
Objective To investigate the incidence of post-stroke depression (PSD) and its risk factors, so as to provide theoretical reference for prevention community PSD. Methods A total 300 stroke patients hospitalized in department neurology First Bethune Hospital Jilin University from July 2016 May 2017 were selected assessed by Self-rating Depression Scale (SDS) Hamilton (HAMD) on their depression. The PSD was analyzed after controlling confounding relation between relevant influencing...
Since the first strain related to Thermicanaceae was reported in 1999, almost no literature on is available, particularly its genomics. We recently isolated a novel pathogenic bacterium, △ DYY3, from blood sample of critically ill patient. The morphological, physiological, and biochemical characteristics DYY3 were presented this study, virulence factor genes antibiotic resistance also determined. Interestingly, average nucleotide identity (ANI) core-genes amino acid (cAAI) analysis indicated...