Abstract Aims Concerns have been raised regarding the potential causal relationship between myocarditis and mRNA COVID-19 vaccines. In response, Korea Disease Control Prevention Agency actively monitored pericarditis in adolescents who received vaccines South Korea. Understanding long-term health outcomes of these cases is essential for developing evidence-based national policies. We aimed to identify health-related quality life (HRQoL) through follow-up observations this population. Methods...

Purpose: Atopic dermatitis (AD), allergic rhinitis (AR), and bronchial asthma (BA) are major diseases in childhood. Pediatric characterized by the ‘atopic march,’ where two or more conditions can occur either simultaneously sequentially. MicroRNAs (miRNAs) serve as fine regulators of gene expression, capable modulating clinical manifestations post-transcriptionally. We investigated miRNAs commonly expressed these three to enhance understanding their development management. Methods: collected...

Abstract Background Recent data suggested that dysbiosis of the gut microbiome is associated with childhood allergic diseases. Oral administration probiotic formulations may improve severity atopic dermatitis (AD) by restoring imbalanced microbiota and reducing intestinal inflammation in children. Objectives The aim this study was to investigate effects a mixture on clinical AD, inflammatory markers alterations children AD. Methods A total 25 subjects were enrolled administered strains...

Congenital heart disease (CHD) is a known risk factor for acquired cardiovascular and cerebrovascular diseases. However, available evidence on CHD limited mostly to Western populations. This study aimed evaluate the prevalence of vascular events all-cause mortality in Korean patients with further corroborate as predictor mortality.The claims data National Health Insurance Service (NHIS) were retrospectively reviewed. Information regarding diagnostic codes, comorbidities, medical services,...

Maternal heart disease is suspected to affect preterm birth (PTB); however, validated studies on the association between maternal and PTB are still limited. This study aimed build a prediction model for using machine learning analysis nationwide population data, investigate various diseases PTB.A population-based, retrospective cohort was conducted data obtained from Korea National Health Insurance claims database, that included 174,926 primiparous women aged 25-40 years who delivered in...

We investigated the association between obesity and cardiovascular disease risk factors (CVDRFs) in adolescents. performed a cross-sectional study using data from 8149 adolescents, aged 10-18 years, included Korean National Health Nutrition Examination Survey (2011-2020). Using body mass index, we defined "overweight" (≥85th to <95th percentile) "obese" (≥95th percentile). analyzed associations CVDRFs (high blood pressure, abnormal lipid profiles, high fasting glucose levels) by sex age...

To examine the correlation of depression with Internet use and body image perception, to analyze risk factors in a total 920 students Seoul, Korea.Students were recruited by contacting school principals teachers encouraged fill out self-report questionnaire designed specifically for this study July 2008.Female participants had an increased than did male (adjusted odds ratio [aOR], 1.790; 95% confidence interval [CI], 1.330-2.410, P<0.001). Older more susceptible (aOR, 1.246; CI, 1.115-1.392,...

It has been shown that aerobic exercise improves atopic dermatitis (AD), although the mechanism is not clear. Here, we propose a hypothesis moderate-intensity AD in mouse model through modulating allergic inflammation. The DNCB-treated for eczema was divided into 3 groups: (a) subjected to exercise, (b) continuous and (c) accumulated exercise. After given using treadmill device either 30 min/d or 10 min × 3/day at speed of 16 m/min, 9 days, respectively, symptom score, thickness...

To the editor, School closure during coronavirus disease 2019 (COVID-19) pandemic reduced physical activity and aggravated obesity in children. 1) Obesity is a major risk factor for metabolic syndrome (MS). 2)Obesity-related asthma characterized by more severe phenotype. 3,4)Previous studies have demonstrated that childhood not only associated with increased incidental asthma, severity, morbidity, but also has significant effects on lung function. 5,6)A rapid increase COVID-19 highlights...

Abstract This cross-sectional study aimed to develop and validate population-based machine learning models for examining the association between breastfeeding metabolic syndrome in women. The artificial neural network, decision tree, logistic regression, Naïve Bayes, random forest support vector were developed validated predict Data came from 30,204 women, who aged 20 years or more participated Korean National Health Nutrition Examination Surveys 2010–2019. dependent variable was syndrome....

This study aimed to investigate the epidemiological characteristics and outcomes of myocarditis/pericarditis after BNT162b2 vaccination in Korean adolescents.

Congenital tuberculosis (TB) is a rare disease that associated with high mortality. Mycobacterium tuberculosis, the causative agent, may be transmitted from infected mother to fetus by transplacental route or aspiration of amniotic fluid. Clinical symptoms and signs are not specific. Miliary patterns most common findings in chest X-rays many infants congenital TB. In this case, an 18-day-old boy had jaundice on fifth day birth, fever respiratory distress appeared 18th day. Chest X-ray showed...

While the association of congenital heart disease (CHD) and growth retardation (GR) is known, data remain limited. This study investigated incidence GR its neonatal risk factors in patients with CHD using nationwide population-based claims data.The population was extracted from Korean National Health Insurance Service January 2002 to December 2020. We included diagnosed under one year age. defined as an idiopathic hormone deficiency or short stature on data. for GR.The number within first...

High waist circumference (WC) is associated with increased cardiovascular risk (CVR) in adulthood. We investigated this association adolescents.We performed a cross-sectional analysis of data for 10-18-year-olds included the Korea National Health and Nutrition Examination Survey (KNHANES) (2005-2014). The between WC CVR factors was evaluated. analyzed relationship according to age.We 8,153 participants (4,319 boys 3,834 girls) from KNHANES. incidence factors: hypertension (odds ratio [OR],...

We conducted a cohort study to estimate the impact of social distancing on incidence Kawasaki disease (KD) in Korean children, using nationally representative data. The KD-related hospitalization rate has declined significantly from -38.8% (April) 81.7% (June). decrease diagnosis KD adds clue for infectious etiology and establishment preventive measures.

Many Down syndrome (DS) patients have an atrial septal defect (ASD) and associated pulmonary hypertension (PH) from early childhood. ASD closure in DS with PH is often controversial due to concerns regarding exacerbation of PH. The aim this study was investigate the clinical outcome following surgical children DS.We retrospectively reviewed medical records who underwent patch January 2000 December 2016.A total 15 surgery for ASD. Prior closure, nine were diagnosed PH, three whom took...

Abstract A 29-month-old girl had idiopathic massive pericardial effusion for over 6 months. Lymphangiography was performed chronic and recurrent pulmonary lymphangiectasia, suspected based on CT findings. Magnetic resonance lymphangiography revealed chylolymphatic reflux from a tortuously dilated thoracic duct in the mediastinum to space, suggesting primary chylopericardium with lymphangiectasia. Pericardial resolved immediately after embolisation at lower level. However, recurred 5 months,...

Objective: It is currently unknown whether closing atrial septal defects (ASDs) could reduce cardiovascular events and mortality in adult patients with ASD. This study aims to investigate the long-term effects of different ASD closure methods on adults. Methods: We conducted a retrospective analysis Korean National Health Insurance Service benefit records spanning from 2002 2020. From this dataset, we identified aged 20 years or older who received diagnosis based ICD-10 codes between 2004...