A5058641633- SARS-CoV-2 and COVID-19 Research
- Respiratory viral infections research
- Viral Infections and Immunology Research
- COVID-19 Clinical Research Studies
- Cytomegalovirus and herpesvirus research
- Long-Term Effects of COVID-19
- Pneumonia and Respiratory Infections
- Herpesvirus Infections and Treatments
- Vaccine Coverage and Hesitancy
- Virus-based gene therapy research
- Influenza Virus Research Studies
- Viral Infections and Vectors
- Infective Endocarditis Diagnosis and Management
- Hepatitis B Virus Studies
- Animal Virus Infections Studies
- Streptococcal Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Emergency and Acute Care Studies
- Curcumin's Biomedical Applications
- Coronary Artery Anomalies
- Health Systems, Economic Evaluations, Quality of Life
- Tracheal and airway disorders
- Hepatitis Viruses Studies and Epidemiology
- Muscle and Compartmental Disorders
- Pulmonary Hypertension Research and Treatments
Seoul National University Children's Hospital
2020-2025
Seoul National University
2009-2025
Boramae Medical Center
2025
Yeouido St. Mary's Hospital
2024
Catholic University of Korea
2024
Pediatrics and Genetics
2022
New Generation University College
2022
Seoul National University Hospital
2020
Data on the clinical characteristics of pediatric patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant infection are limited. We aimed to evaluate features and outcomes children SARS-CoV-2 before after omicron dominance in Korea.A multicenter retrospective cohort study was conducted hospitalized aged ≤ 18 years laboratory-confirmed at five university hospitals South Korea. The periods were divided into delta (from August 23, 2021 January 2, 2022) 30 March 31,...
Background: The COVID-19 pandemic’s transition to an endemic phase emphasizes the importance of vaccination. Despite initial strong immunogenicity, waning vaccine-induced immunity requires further investigation. Therefore, this study evaluated immunogenicity BNT162b2 vaccine in adolescents, focusing on spike-specific and neutralizing antibody kinetics following primary booster vaccinations as well impact breakthrough infections. Methods: This observational included 157 adolescents 12–17...
Abstract Aims Concerns have been raised regarding the potential causal relationship between myocarditis and mRNA COVID-19 vaccines. In response, Korea Disease Control Prevention Agency actively monitored pericarditis in adolescents who received vaccines South Korea. Understanding long-term health outcomes of these cases is essential for developing evidence-based national policies. We aimed to identify health-related quality life (HRQoL) through follow-up observations this population. Methods...
Parainfluenza virus type 3 (PIV3) and respiratory syncytial (RSV) B epidemics occurred in South Korea late 2021. We investigated epidemiological changes of PIV3 RSV infections Korean children before during the coronavirus disease 2019 (COVID-19) pandemic.In this multicenter retrospective study, we enrolled patients aged less than 19 years with or infection four university hospitals from January 2018 to 2022. Demographic clinical data were extracted subject's medical records analyzed for each...
Korean health authority plans to vaccinate adolescents against coronavirus disease 2019 (COVID-19) starting high school seniors during the summer vacation of 2021. However, myocarditis/pericarditis following COVID-19 vaccine has been reported recently in and young adults. This study was performed answer urgent questions about basic epidemiology clinical course hospitalized patients prior introduction vaccines pediatric population.A retrospective medical record analysis including frequency,...
Although much interest has emerged regarding post-COVID conditions, data on children and adolescents are limited. The prevalence of long COVID common symptoms were analyzed in this case-control study 274 children. Prolonged non-neuropsychiatric more frequent the case group (17.0% 4.8%, P = 0.004). Abdominal pain (6.6%) was most symptom.
This study aimed to investigate the epidemiological characteristics and outcomes of myocarditis/pericarditis after BNT162b2 vaccination in Korean adolescents.
Omicron, a recent variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is currently globally dominating. We reviewed the etiology and epidemiology croup over an approximately 5-year period, with emphasis on dominance Omicron variant. Children less than 5 years age seen in emergency department diagnosis from two large national tertiary hospitals were collected for period January 2018 through March 2022. Viral etiologies patients compared surveillance data upon circulating...
Diagnostic methods for pulmonary tuberculosis (TB) have recently advanced. The aim of this study was to evaluate the changes in TB diagnostic tests that prompted initiation anti-TB treatment over time South Korea, an industrialized country with intermediate burden.Patients diagnosed first halves 2005 and 2013 at a tertiary referral hospital were included. compared between 2 groups patients.A greater proportion patients using bronchoscopy than (26.7% vs. 6.6%, respectively; p<0.001), while...
The risk of severe outcomes with acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant remains low in children and adolescents, but less is known about its effect on the SARS-CoV-2-naïve population. This study evaluated clinical manifestations factors for moderate-to-critical disease 2019 (COVID-19) mostly adolescents 2021.This multicenter retrospective included patients aged 0-18 years who were hospitalized COVID-19 at 8 referring hospitals South Korea during...
There have been many epidemiologic studies on community-acquired pneumonia (CAP) among children, most of which had substantial limitations. This study investigated the etiologic distribution and clinical characteristics CAP in Korean children for 5 years before coronavirus disease 2019 (COVID-19) pandemic.A retrospective analysis hospitalized at 4 referral hospitals during 2015-2020 was performed. Cases bronchiolitis suspected or pulmonary infiltration not evident chest radiography (CXR)...
ObjectivesIn Korea, the National Immunization Program provided trivalent inactivated influenza vaccines (IIV3) to all children aged 6–59 months during 2017–2018 season. In this study, we aimed evaluate vaccine effectiveness (VE) of IIV3 in season.MethodsChildren who were tested for their acute respiratory illness four hospitals season included. We estimated VE by test-negative case-control design based on rapid diagnostic test (RIDT) or reverse transcription polymerase chain reaction...
Vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been acknowledged as an effective mean of preventing infection and hospitalization. However, the emergence highly transmissible SARS-CoV-2 variants concern (VOCs) led to substantial increase in infections among children adolescents. Vaccine-induced immunity longevity have not well defined this population. Therefore, we aimed analyze humoral cellular immune responses ancestral after two shots BNT162b2 vaccine...
The Korea Expert Committee on Immunization Practices (KECIP) is a key advisory body the government to develop guidelines and provide technical activities immunization policies in Korea. A recent policy study, inspired by global best practices, aims enhance KECIP's functionality for providing timely transparent recommendations face of evolving vaccine science emerging infectious diseases like COVID-19. This study reviewed current status KECIP collected expert opinions through surveys...
Background: Varicella can lead to severe complications in immunocompromised children, including those undergoing hematopoietic stem cell transplantation (HSCT) or chemotherapy. Preventing primary varicella zoster virus (VZV) infection is crucial these populations mitigate morbidity and mortality. This study aimed evaluate the immunogenicity safety of live attenuated MAV/06 vaccine pediatric patients post-HSCT post-chemotherapy. Additionally, it sought compare...
Abstract Background Children that have undergone hematopoietic stem cell transplantation (HSCT) are at a higher risk for severe influenza. The purpose of this study was to compare the duration antibodies after immunization with quadrivalent influenza vaccine (QIV) in children or chemotherapy compared healthy children. Methods This prospective below 18 years old received QIV during 2021-2022 vaccination season. were divided into 3 groups as follows: a) post-HSCT, b) post-chemotherapy, and c)...
Consensus cytomegalovirus (CMV) DNA viral load thresholds for intervention in hematopoietic stem cell transplant (HSCT) recipients have not been established, especially children. This study aimed at obtaining of CMV to guide preemptive management pediatric HSCT recipients.A total 465 blood samples from 177 children who received between 2015 and 2019 were included a single center Korea. The analyzed infection by both antigenemia assay quantitative polymerase chain reaction. 2 results compared...