- Congenital Heart Disease Studies
- Cardiovascular Issues in Pregnancy
- Pregnancy and preeclampsia studies
- Congenital heart defects research
- Coronary Interventions and Diagnostics
- Tracheal and airway disorders
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Tumors and Oncological Cases
- Renal and related cancers
- Cardiac Structural Anomalies and Repair
- Congenital Diaphragmatic Hernia Studies
- Prenatal Screening and Diagnostics
- Tuberous Sclerosis Complex Research
- RNA modifications and cancer
- Renal and Vascular Pathologies
- Cardiovascular and Diving-Related Complications
- Cardiac tumors and thrombi
- Medical Coding and Health Information
- Lipoproteins and Cardiovascular Health
- HIV Research and Treatment
- Pulmonary Hypertension Research and Treatments
- Phonocardiography and Auscultation Techniques
Beijing Anzhen Hospital
2011-2025
Capital Medical University
2012-2025
Beijing Shijitan Hospital
2025
Beijing YouAn Hospital
2015-2025
Beijing Anding Hospital
2011-2014
To analyze the imaging and clinical features of fetal cardiac tumors, to explore relationship between tuberous sclerosis complex (TSC) rhabdomyoma in fetus.Fifty-three women pregnant with a fetus affected by tumor(s) were examined standardized echocardiography (FE), fetuses, mothers fathers, including other relevant family members if necessary, underwent familial TSC genetic testing. Relevant pathological features, findings at examination liveborn infants autopsy terminated cases, noted.Of...
Background Data on the predictive value of coronary computed tomography angiography–derived fractional flow reserve (CT‐FFR) for long‐term outcomes are limited. Methods and Results A retrospective pooled analysis individual patient data was performed. Deep‐learning‐based CT‐FFR calculated. All patients enrolled were followed‐up at least 5 years. The primary outcome major adverse cardiovascular events. secondary death or nonfatal myocardial infarction. Predictive abilities compared among 3...
Pneumocystis pneumonia (PCP) is a common and serious complication of HIV/AIDS, with higher prevalence in patients not receiving antiretroviral therapy. Due to the high mortality rate PCP, accurate prediction its case fatality very important for clinical treatment. We aimed develop risk model near-term prognosis people HIV/AIDS PCP verify effectiveness. This single-center, retrospective observational study was conducted at Beijing Youan Hospital from January 2012 October 2022. 972 AIDS met...
<title>Abstract</title> <bold>Purpose</bold> The goal of this study was to explore whether the clinical benefits percutaneous coronary intervention (PCI) are sustained in acute syndrome (ACS) patients with abnormally increased platelet counts (PC). <bold>Methods</bold> Patients elevated PC enrolled Improving Care for Cardiovascular Disease China<bold>–</bold>Acute Coronary Syndrome Project between July 1, 2017, and December 31, 2019 were evaluated. Elevated defined as a baseline ≥ 300 ×...
Some pregnant women with congenital heart disease have cardiac insufficiency and pulmonary artery hypertension. The complication during perinatal period is higher than normal people. newborns often occur premature birth, low birth weight, asphyxia so on. In this study, we sought to analyse the condition of newborns. A total 456 at Beijing An Zhen Hospital/Beijing Heart Lung Institute from 2006 2016 were retrospectively reviewed. clinical echocardiographic data analysed. findings compared...
To investigate the echocardiographic diagnosis for fetal ventricular non-compaction cardiomyopathy (VNCC) and to analyse genetic associations with VNCC. A total of 13 fetuses were diagnosed as VNCC from 30009 studies in Beijing Anzhen Hospital September 2010 February 2018. Fetal umbilical cord tissue samples parental pewere collected after families opted termination pregnancy, addition peripheral blood parents. Whole-exome sequencing (WES) Sanger performed using biological specimens. In this...
To summarise the fetal echocardiography characteristic and prognosis in agenesis of ductus venosus (ADV) with abnormal umbilical vein connection patients. Retrospective analysis 14 fetuses ADV by echocardiography. Analysis size heart, changes heart function prognosis. cases have been detected since January 2011 to November 2014. In six them was connected portal (five left one right), whereas neither drained nor right other eight cases. The extrahepatic venous system tracking detection...
Prenatal diagnosis and assessment of Ebstein anomaly (EA) requires quantitative measurement displacement tricuspid valve. In this study, we assessed the traditional new measures to evaluate EA attempt define cut-off values in fetuses for EA. A total 15 with EA, 34 moderate severe regurgitation, mild regurgitation structural normal hearts between October 2010 2014 at our institution were studied. Nine variables measured four chamber views, including: 1) mitral-tricuspid valve distance (MTD),...
It has been a challenge to quantitatively assess global and regional ventricular function in hypoplastic left heart syndrome (HLHS), especially fetuses. The aim of this study was evaluate longitudinal systolic fetuses with HLHS using velocity vector imaging (VVI) determine the influence gestational age on these variables. Twenty were enrolled during second third trimester (20–35 weeks). control group 1:1 paired normal Two-dimensional grayscale image clips high frame rates obtained from...
Premature restriction and closure of foramen ovale (FO) is associated with right ventricular remodeling, tricuspid regurgitation, pericardial effusion, heart failure poor perinatal outcomes but data lacking in this rare entity. A total 9704 fetuses were studied Beijing Anzhen Hospital from 2010 to 2014. complete fetal echocardiogram, including two-dimensional imaging, colour pulse Doppler, was performed ascertain the presence and/or FO or without septal aneurysm. Restriction defined as: (1)...
To retrospectively analysed echocardiographic characteristics of ventricular diverticula in fetuses, children and adults. Echocardiographic 8 3 12 adults were summarised, including the position, type size diverticula, other cardiac extracardiac abnormalities. Meantime, clinical histories, accessory examinations, intraoperative findings cases collected outcomes fetal followed up. There muscular 5 fibrous cases. 2 born, terminated pregnancy lost to follow 1 diverticulum, found Of 14 adult...
To analyse the echocardiographic features of absent pulmonary valve syndrome (APVS). The findings were retrospectively analysed in seven fetuses with APVS and summarised. Of all APVS, which demonstrated cardiac enlargement, axis heart was to left main artery or branches significantly dilated. rudimentary. Colour Doppler flow imaging severe regurgitation. Spectral showed stenosis annulus. Four associated tetralogy Fallot, one case small foci ventricle single umbilical artery. Two right aortic...
In this study, we sought to investigate the accuracy of prenatal echocardiographic screening and diagnosis congenital heart defect (CHD) by a regional referral centre, i.e. Beijing Anzhen Hospital fetal echocardiography laboratory, compared with registry birth defect, population-based surveillance system on defect. A second aim is assess limitations quality improvement measures for CHD. We studied all 8522 echocardiograms from September 1, 2012 December 31, 2014 in our institution. Among...
Fetal cardiac rhabdomyoma can be the initial finding in patients with tuberous sclerosis complex (TSC). The aim of this study is to correlate mutations TSC1 and TSC2 genes fetuses ascertain incremental value genetic analysis screening TSC. We retrospectively analysed 7559 fetal echocardiograms from January 2013 September 2015 our institution. A total 24 were diagnosed heart tumours 10 rhabdomyomas. Samples cardiac, umbilical cord, deltoid or other tissues and/or peripheral blood obtained...
The specific aims of the study are to explore correlation between genotypes and phenotypes congenital heart defects (CHD) diagnosed by fetal echocardiography develop strategies for antenatal screening integrated diagnosis, prognosis counselling CHDs. A total 62 fetuses with CHDs in Beijing Anzhen Hospital (Beijing, China) verified postmortem examination were prospectively enrolled this from January 2013 July 2015. Low-coverage Whole Genome Sequencing (∼1×) was used detect chromosomal...
Recent studies have validated that fetal echocardiography can sensitively and specifically identify complete vascular rings (VR), which cause significant respiratory GI compromise after birth. However, quantitative measures for prognosis guiding counselling postnatal treatment are lacking. We sought to measure tracheal ring area (TA VRA) as potential variables of outcome VR. conducted a retrospective study 92 fetuses with isolated VR diagnosed by prenatally confirmed echocardiography, from...
To establish normal reference ranges of fetal cardiac dimensions between 20 and 34 per weeks including: inner diameter heart arteries, aortic arch isthmus, descending aorta, ducts artery foramen ovale. A cross-sectional study was undertaken on singleton pregnancies with fetuses accurate gestational ages. Totally 2573 fetus divided into 15 groups according to the gestation. All measurements were stored statistic value range analyze correlation these measurementsand gestation age. 1. In fetus,...
Mitral valve dysplasia associated with severe MR and other cardiac structural functional abnormalities, such as aortic stenosis (AS), left heart dilation, intact atrial septum or restrictive foramen ovale, is a rare constellation of abnormalities in fetal heart. It unique form left-sided disease, may be summed up mitral syndrome (MVDS)[1]. A case 30 gestational weeks fetus gradually development MVDS was reported. indicated that might progressive disease.