- Plant Pathogens and Fungal Diseases
- Mycorrhizal Fungi and Plant Interactions
- Fungal Biology and Applications
- Microbial Natural Products and Biosynthesis
- Gut microbiota and health
- Nematode management and characterization studies
- Entomopathogenic Microorganisms in Pest Control
- Yeasts and Rust Fungi Studies
- Plant-Microbe Interactions and Immunity
- Genomics and Phylogenetic Studies
- Polysaccharides and Plant Cell Walls
- Antifungal resistance and susceptibility
- Genetics, Aging, and Longevity in Model Organisms
- Liver Disease Diagnosis and Treatment
- Insect and Arachnid Ecology and Behavior
- Microbial Community Ecology and Physiology
- Lichen and fungal ecology
- Diet and metabolism studies
- Fungal and yeast genetics research
- Plant Disease Management Techniques
- Plant and fungal interactions
- Diatoms and Algae Research
- Mycotoxins in Agriculture and Food
- Infant Nutrition and Health
- Parasite Biology and Host Interactions
Chinese Academy of Sciences
2015-2025
University of Chinese Academy of Sciences
2023-2025
Institute of Microbiology
2014-2024
Institute of Vegetables and Flowers
2018
Chinese Academy of Agricultural Sciences
2018
Mae Fah Luang University
2014-2017
Czech Academy of Sciences, Institute of Microbiology
2013
Draft genomes of the species Annulohypoxylon stygium, Aspergillus mulundensis, Berkeleyomyces basicola (syn. Thielaviopsis basicola), Ceratocystis smalleyi, two Cercospora beticola strains, Coleophoma cylindrospora, Fusarium fracticaudum, Phialophora cf. hyalina and Morchella septimelata are presented. Both mating types (MAT1-1 MAT1-2) included. Two strains cylindrospora that produce sulfated homotyrosine echinocandin variants, FR209602, FR220897 FR220899 The sequencing has enabled mapping...
Rock-inhabiting fungi (RIF) are nonlichenized that naturally colonize rock surfaces and subsurfaces. The extremely slow growth rate lack of distinguishing morphological characteristics RIF resulted in a poor understanding on their biodiversity. In this study, we surveyed colonizing historical stone monuments natural formations from throughout China. Among over 1000 isolates, after preliminary delimitation using the internal transcribed spacer region (ITS) sequences, representative isolates...
Abstract Some species of Trichoderma are fungicolous on fungi and have been extensively studied commercialized as biocontrol agents. Multigene analyses coupled with morphology, resulted in the discovery T. hypoxylon sp. nov., which was isolated from surface stroma Hypoxylon anthochroum . The new taxon produces - to Verticillium -like conidiophores hyaline conidia. Phylogenetic based combined ITS, TEF1-α RPB2 sequence data indicated that is a well-distinguished strong bootstrap support...
The human gut microbiota has gained interest as an environmental factor that contributes to health or disease. development of next-generation live biotherapeutic products (LBPs) is a promising strategy modulate the and improve health. In this study, we identified novel cross-feeding interaction between Bacteroides xylanisolvens Clostridium butyricum developed their combination into LBP for treating metabolic syndrome. Using in-silico analysis in vitro experiments, demonstrated B. supported...
The echinocandins are a class of antifungal drugs that includes caspofungin, micafungin, and anidulafungin. Gene clusters encoding most the structural complexity provided framework for hypotheses about evolutionary history chemical logic echinocandin biosynthesis. orthologs among echinocandin-producing fungi were identified. Pathway genes, including nonribosomal peptide synthetases (NRPSs), analyzed phylogenetically to address hypothesis these pathways represent descent from common ancestor....
The Harzianum clade of Trichoderma comprises many species, which are associated with a wide variety substrates. In this study, four new species , namely T. lentinulae vermifimicola xixiacum and zelobreve were encountered from fruiting body compost Lentinula soil, vermicompost. Their colony mycelial morphology, including features asexual states, described. For each their DNA sequences obtained three loci, the internal transcribed spacer (ITS) regions ribosomal DNA, gene encoding second...
Methicillin-resistant Staphylococcus aureus (MRSA), a WHO high-priority pathogen that can cause great harm to living beings, is primary of death from antibiotic-resistant infections. In the present study, six new compounds, including fumindoline A–C (1–3), 12β, 13β-hydroxy-asperfumigatin (4), 2-epi-tryptoquivaline F (17) and penibenzophenone E (37), thirty-nine known ones were isolated marine-derived fungus Aspergillus fumigatus H22. The structures absolute configurations compounds...
Abstract Prolonged alcohol consumption disrupts the gut microbiota and immune system, contributing to pathogenesis of alcohol‐associated liver disease (ALD). Probiotic‐postbiotic intervention strategies can effectively relieve ALD by maintaining homeostasis. Herein, efficacy heat‐killed Lactobacillus johnsonii (HKLJ) in mitigating alcoholic damage is demonstrated mouse models ALD. The gut‐liver axis identified as a pivotal pathway for protective effects L. against Specifically, HKLJ found...
Sugarcane leaves-derived polyphenols (SLP) have been demonstrated to diverse health-promoting benefits, but the mechanism of action has not fully elucidated. This study aimed investigate anti metabolic disease effects SLP and underlying mechanisms in mice. In current study, we prepared mainly consisting three flavonoid glycosides, phenol derivatives, two lignans including one new compound, further that reduced body weight gain fat accumulation, improved glucose lipid metabolism disorders,...
Nematicides are the main method for managing root-knot nematodes but they not environmentally benign. Biological control is one alternative that has a lower or no environmental impact. This study was conducted to evaluate efficacy of two nematicides (Fosthiazate and Dazomet), biocontrol agent ( Purpureocillium lilacinum (= Paecilomyces lilacinus ) YES-2), their combination on controlling tomato plants effects rhizosphere microbial community in long-term glasshouse experiments. The gall index...
During a field survey of cultivated Morchella mushroom diseases, Diploöspora longispora and Paecilomyces penicillatus, causal agents pileus rot or white mould disease were detected, which resulted in up to 80% yield losses. Multi-locus phylogenic analysis revealed that the fungi affiliated distinct clade Hypocreales. We further constructed phylogenetic tree with broader sampling Hypocreales estimated divergence times. The D. P. penicillatus clades have diverged from Hypocreaceae around 129...
Abstract Hirsutella rhossiliensis and H. minnesotensis are endoparasitic fungi of the second-stage juvenile (J2) soybean cyst nematode ( Heterodera glycines ) in nature. They also parasitize both J2 Caenorhabditis elegans on agar plates. Agrobacterium tumefaciens -mediated transformation conditions were established for these spp. The resulting transformants similar to corresponding wild-type strains. infection processes C. second larval stage (L2) by expressing ZsGreen microscopically...
Production of the medicinal and edible fungus Cordyceps militaris has dramatically increased in China because its alleged properties. During industrial production, a fungal parasite was found to infect fruiting bodies causing significant quality yield losses. Two isolates were obtained from C. Beijing Shanghai mushroom farms characterized by morphological phylogenetic analyses SSU ITS sequence data. The showed that they belong genus Calcarisporium are related type species, arbuscula with 91%...