Anastasia A. Tsintsadze

ORCID: 0000-0003-1897-0331
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About
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Research Areas
  • Anesthesia and Neurotoxicity Research
  • Anesthesia and Pain Management
  • Ocular Oncology and Treatments
  • Blood transfusion and management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Intraocular Surgery and Lenses
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Muscle and Compartmental Disorders
  • Congenital Heart Disease Studies
  • Pediatric Pain Management Techniques
  • Ocular Infections and Treatments
  • Pain Management and Opioid Use
  • Abdominal Surgery and Complications
  • Dental Anxiety and Anesthesia Techniques
  • Nausea and vomiting management
  • Hernia repair and management
  • Head and Neck Surgical Oncology
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Tracheal and airway disorders
  • Retinal and Optic Conditions
  • Nasal Surgery and Airway Studies
  • Neuroscience of respiration and sleep
  • Cardiovascular and Diving-Related Complications
  • Transplantation: Methods and Outcomes
  • Cardiovascular Conditions and Treatments

Sechenov University
2024

Ministry of Health
2021-2024

National Medical Research Center of Cardiology
2024

Russian Cancer Research Center NN Blokhin
2024

Ministry of Health of the Russian Federation
2021-2023

1Jo Ann Medical Center, Dept of Intensive Care, Tbilisi, Georgia, 2Jo Surgery, Georgia

10.1097/00003643-201406001-00251 article EN European Journal of Anaesthesiology 2014-06-01

BACKGROUND: Certain children with recurrent episodes of acute nociceptive pain experience chronic pain. In accordance the recommendations World Health Organization, short-acting morphine is main drug used to relieve severe and breakthrough published studies, provided adequate analgesia in majority (90%) patients; however, no such studies have compared use tablets a control group pediatric patients.
 OBJECTIVE: To evaluate effectiveness safety at dose 5 mg compare them those given...

10.17816/ra568648 article EN Regional Anesthesia and Acute Pain Management 2024-01-24

Introduction . Massive perioperative blood loss that accompanies major surgical interventions is a specific critical condition, the pathogenesis of which dominated by severe hypovolemia, anemia, and threatening coagulopathy in combination with powerful shockogenic sympathoadrenal stress. Both massive itself transfusion are associated significant risk serious complications, including death. It worth noting information on survival patients after replacement several circulating volume (CBV)...

10.24884/2078-5658-2024-21-1-100-109 article EN cc-by Messenger of Anesthesiology and Resuscitation 2024-02-22

BACKGROUND: Thoracic epidural anesthesia is the gold standard for postoperative analgesia after thoracic surgery; its alternatives include paravertebral block (PVB) and erector spinae plane (ESPB). However, ESPB has not been evaluated in comparison with intraoperative PVB effectiveness speed of recovery early period thoracoscopic surgery children cancer. AIM: Our aim was to investigate analgesic muscle compared intra during surgical interventions tumors. MATERIALS AND METODS: A prospective,...

10.17816/ra629321 article EN Regional Anesthesia and Acute Pain Management 2024-08-01

BACKGROUND: In the protocols of rapid recovery after surgery, it is recommended to avoid long-term administration and/ or high doses opioids in order reduce severity their adverse reactions postoperative period. this regard, opioid-sparing anesthesia (OSA) may become a promising approach treatment cancer patients. AIM. To evaluate effectiveness multimodal OSA scheme "dexmedetomidine+ketamine (in subanesthetic doses)+lidocaine (intravenous infusion)" pediatric oncosurgery. MATERIALS AND...

10.17816/ra630631 article EN Regional Anesthesia and Acute Pain Management 2024-10-15

BACKGROUND: Effective anesthesia is one of the most important factors in rapid and successful rehabilitation after surgery. Inadequately selected analgesia consequent pain significantly slow down recovery process are associated with several complications that cover almost all organs systems reduce patients quality life long term.
 OBJECTIVE: This study aimed to analyze 6 years clinical experience perioperative epidural Research Institute Pediatric Oncology, considering effectiveness,...

10.17816/ra110736 article EN Regional Anesthesia and Acute Pain Management 2023-03-19

Introduction . Retinoblastoma (RB) is a malignant tumor of the retina, survival rate for intraocular form reaches 99 %. According to researchers, risk factors occurrence refractory or recurrent forms RB are size at primary diagnosis (more than 15 mm), child's age onset disease (up one year), bilateral RB, and presence subretinal vitreal screenings. If methods local destruction not applicable successful treatment then they resort second line polychemotherapy as an alternative enucleation. New...

10.21682/2311-1267-2020-7-4-15-34 article EN Russian Journal of Pediatric Hematology and Oncology 2021-01-07

BACKGROUND: The retrobulbar block in children is used to enucleate analgesia the intra- and postoperative period prevent oculocardiac reflex (OCD), nausea, vomiting. However, when performed blindly, it results serious complications.
 AIM: This study aimed evaluate efficacy safety of a under ultrasound guidance compared with blindly during enucleation eyeball retinoblastoma.
 MATERIALS AND METHODS: A prospective randomized controlled trial was performed. included 40 patients who met...

10.17816/1993-6508-2021-15-2-127-136 article EN Regional Anesthesia and Acute Pain Management 2021-12-28

Introduction. Regional blockades in children ophthalmology operations are used not only for analgesia the intra- and postoperative period, but also prevention of oculocardial reflex (OCR), nausea vomiting (PONV). But there is still no convincing data on advantages methods retrobulbar blockade (RBB) performed under ultrasound guidance parabulbar (PBB) guidance. Aim. In present study, we investigated efficacy safety RBB with ropivacaine 0.5 % OCR pain, as well PONV when detected PBB upon...

10.21682/2311-1267-2022-9-4-37-43 article EN Russian Journal of Pediatric Hematology and Oncology 2023-02-01

Aiml. Optimization of anesthesia during enucleation the eyeball in pediatric oncosurgery with an emphasis on regional methods. Material and Methods. Eight anesthesias were performed children, whose average age was 3 years, operated for retinoblastoma from July 2021 to January 2022. All patients underwent combined endotracheal anesthesia. A triple block used as a component: palatal anesthesia, infraorbital van Lint block. Results. The effectiveness adequacy proposed method using assessed...

10.25276/2686-6986-2022-1-55-59 article EN Reflection 2022-06-07

BACKGROUND: According to world statistics, about 15% of all malignant tumors are localized in the nasal cavity and rhinopharynx. Endoscopic rhinolaryngosurgery is considered be low-traumatic. Combining general anesthesia with regional improves quality operation ensures effectiveness safety surgical intervention. To optimize anesthetic support for endoscopic pediatric rhinolaryngology, we proposed a method combining bilateral cranial palatal access (or palatine) guarantee perioperative...

10.17816/1993-6508-2021-15-4-287-296 article EN Regional Anesthesia and Acute Pain Management 2022-06-18
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