A5068674927- Thyroid Cancer Diagnosis and Treatment
- Global Cancer Incidence and Screening
- BRCA gene mutations in cancer
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Nutritional Studies and Diet
- Air Quality Monitoring and Forecasting
- Health disparities and outcomes
- Genetic factors in colorectal cancer
- Energy and Environment Impacts
- Cancer Risks and Factors
- Thyroid Disorders and Treatments
- Colorectal Cancer Screening and Detection
- Radiation Dose and Imaging
- Health, Environment, Cognitive Aging
- Thyroid and Parathyroid Surgery
- Cancer survivorship and care
- Ovarian cancer diagnosis and treatment
- Neuroendocrine Tumor Research Advances
- Cardiovascular Health and Risk Factors
- Head and Neck Anomalies
- Smoking Behavior and Cessation
- Testicular diseases and treatments
University of Chicago
2015-2025
Chicago Department of Public Health
2015-2025
Agostino Gemelli University Polyclinic
2022
Institut Pasteur de Lille
2022
Centre Hospitalier Universitaire de Lille
2022
Cedars-Sinai Medical Center
2022
National Institutes of Health
2010-2015
National Cancer Institute
2010-2015
Yale University
2011-2012
United States Department of Health and Human Services
2011
Background: The increasing incidence of thyroid cancer in the United States is well documented. In this study, we assessed patterns by histologic type according to demographic and tumor characteristics further our understanding these cancers. Methods: We used National Cancer Institute's Surveillance, Epidemiology, End Results (SEER) program for cases diagnosed during 1992–2006 investigate four major types gender, race/ethnicity, age as registry, stage, size. Results: Among women, papillary...
Abstract Background: Thyroid cancer incidence is increasing worldwide at an alarming rate, yet little known of the impact this increase will have on society. We sought to determine clinical and economic burden a sustained in thyroid United States understand how these burdens correlate with National Cancer Institute's (NCI) prioritization research funding. Methods: used NCI's SEER 13 database (1992–2009) Joinpoint regression software identify current project future through 2019. combined...
The prevalence of thyroid cancer survivors is rising rapidly due to the combination an increasing incidence, high survival rates, and a young age at diagnosis. physical psychosocial morbidity has not been adequately described, this study therefore sought improve understanding impact on quality life (QoL) by conducting large-scale survivorship study.
The increases in thyroid cancer overall and the predominant papillary type have been well documented, but trends for follicular cancer, a less common more aggressive variant, not as characterized. In this study, we determined incidence patterns compared between cancers United States.
Background: Thyroid cancer incidence has risen steadily over the last few decades in most of developed world, but information on trends developing countries is limited. Sao Paulo, Brazil, one highest rates thyroid worldwide, higher than United States. We examined patterns using data from Paulo Cancer Registry (SPCR) Brazil and National Institute's Surveillance Epidemiology End Results (SEER) program Methods: Data cases diagnosed during 1997–2008 were obtained SPCR (n=15,892) SEER (n=42,717)....
We hypothesized that diabetes may play a role in thyroid cancer risk due to the parallel secular rise prevalence and morbidity United States, higher of disorders among diabetics compared with general population, potential roles metabolic syndrome, obesity, as precipitating factors development.We assessed association between self-reported differentiated NIH-AARP Diet Health Study, prospective cohort 200,556 women 295,992 men, 50-71 years age, 1995-1996. Diabetes status information on...
Nitrate and nitrite are precursors of endogenously formed N-nitroso compounds (NOC), known animal carcinogens. Nitrosation reactions forming NOCs can be inhibited by vitamin C other antioxidants. We prospectively investigated the association between dietary nitrate intake risk colorectal cancer in Shanghai Women's Health Study, a cohort 73,118 women ages 40-70 residing Shanghai. evaluated effect modification factors that affect endogenous formation NOCs: (at or above/below median) red meat...
Background: Follicular thyroid carcinoma (FTC) comprises 10% of differentiated cancers. Diagnostic controversy and interobserver variability render the practical diagnosis FTC difficult. Overall survival rates vary (46–97%). The aims this study were to review histologically at authors' tertiary care institution evaluate long-term recurrence. Methods: slides from 66 cases (1965–2007) reviewed by three pathologists two institutions (blinded clinical outcomes), consensus was obtained. Patient...
Nitrate and nitrite are precursors in the endogenous formation of N-nitroso compounds nitrate can disrupt thyroid homeostasis by inhibiting iodide uptake. We evaluated intake risk cancer Shanghai Women's Health Study that included 73,317 women, aged 40-70 years enrolled 1996-2000. Dietary was assessed at baseline using a food frequency questionnaire. During approximately 11 follow-up, 164 incident cases with complete dietary information were identified. used Cox proportional hazards...
Nitrate is a widespread contaminant of drinking water supplies, especially in agricultural areas. intake from and dietary sources can interfere with the uptake iodide by thyroid, thus potentially impacting thyroid function.We assessed relation estimated nitrate levels well supplies health cohort 2,543 Old Order Amish residing Lancaster, Chester, Lebanon counties Pennsylvania for whom stimulating hormone (TSH) were measured during 1995-2008. measurement data (1976-2006) 3,613 wells study area...
BackgroundWe utilized data from the Health Effects of Arsenic Longitudinal Study (HEALS) in Araihazar, Bangladesh, to evaluate association steamed rice consumption with urinary total arsenic concentration and arsenical skin lesions overall study cohort (N=18,470) a subset available metabolite (N=4,517). MethodsGeneral linear models standardized beta coefficients were used estimate associations between metabolites. Logistic regression prevalence odds ratios (ORs) their 95% confidence...
Animal studies suggest that exposure to pesticides may alter thyroid function; however, few epidemiologic have examined this association. We evaluated the relationship between individual and function in 679 men enrolled a substudy of Agricultural Health Study, cohort licensed pesticide applicators.
Nitrate and nitrite are probable human carcinogens when ingested under conditions that increase the formation of N-nitroso compounds. There have been limited efforts to develop US databases dietary nitrate for standard FFQ. Here we describe development a database its calibration.We analysed data from calibration study 1942 members NIH-AARP (NIH-AARP, National Institutes Health-AARP) Diet Health Study who reported all foods beverages consumed on preceding day in two non-consecutive 24 h...
The impact of race/ethnicity and the additional factors age, sex, socioeconomic status (SES) on follicular lymphoma (FL) outcomes have not been comprehensively studied are well defined. We examined population-based FL data from >18,000 patients in SEER-13 (1992-2009) investigating relevant including SES. Further, we compared over two consecutive periods: Era-1 (1992-2000, n = 8,355) Era-2 (2001-2009, 10,475). identified 18,830 (White: 15,116; Hispanic: 1,627; Asian/Pacific Islander (A/PI):...
Lithium is a naturally occurring element in drinking water and commonly used as mood-stabilizing medication. Although clinical studies have reported associations between receiving lithium treatment reduced cancer risk among patients with bipolar disorder, to our knowledge, the association environmental exposure has never been studied general population. To evaluate groundwater This cohort study included participants electronic health record residential address information but without history...
To analyze racial, ethnic, sex and age disparities in chronic lymphocytic leukemia (CLL), we examined population-based overall survival (OS) data from Surveillance, Epidemiology, End Results (SEER)-13 (1992-2009) across various races/ethnicities over two consecutive 9-year periods: era 1 (1992-2000) 2 (2001-2009). We analyzed 28 590 patients (whites: 24 438, blacks: 1954, Hispanics: 1389 Asians/Pacific Islanders [A/PI]: 809). A higher proportion of whites were aged > 80 years (22% vs. 17%...
Although an increased incidence of mantle cell lymphoma (MCL) has been reported, age-specific patterns have not described. Further analyses could inform investigation into the etiology this disease. We conducted epidemiologic study using 13 Surveillance, Epidemiology, and End Results (SEER) registries to evaluate MCL from 1992 through 2009. calculated proportional changes in for subpopulations defined by age, race/ethnicity gender over time racial/ethnic disparities. observed a 130.9%...