A5018274243- Parathyroid Disorders and Treatments
- Genetic Syndromes and Imprinting
- COVID-19 Impact on Reproduction
- Electrolyte and hormonal disorders
- COVID-19 Clinical Research Studies
- Metabolism and Genetic Disorders
- Blood Pressure and Hypertension Studies
- Poisoning and overdose treatments
- Renal function and acid-base balance
- Neonatal Health and Biochemistry
- Dialysis and Renal Disease Management
- Vitamin D Research Studies
- Fibroblast Growth Factor Research
- Drug-Induced Adverse Reactions
- Biomedical Research and Pathophysiology
- Neurological and metabolic disorders
- Polyomavirus and related diseases
- Cytomegalovirus and herpesvirus research
- Sarcoidosis and Beryllium Toxicity Research
- Complement system in diseases
- Kruppel-like factors research
- Vitamin C and Antioxidants Research
- Hemodynamic Monitoring and Therapy
- Magnesium in Health and Disease
- Blood disorders and treatments
University of Missouri–Kansas City
2018-2022
Children's Mercy Hospital
2015-2022
Mercy Hospital
2019-2022
University of Missouri
2017
There are limited data on the impact of COVID-19 in children with a kidney transplant (KT). We conducted prospective cohort study through Improving Renal Outcomes Collaborative (IROC) to collect clinical outcome about pediatric KT patients. Twenty-two IROC centers that care for 2732 patients submitted testing and outcomes 281 tested SARS-CoV-2 by PCR. Testing indications included symptoms and/or potential exposures (N = 134, 47.7%) per hospital policy 154, 54.8%). Overall, 24 (8.5%)...
Ambulatory blood pressure (BP) monitoring (ABPM) is the preferred method to characterize BP status, and its use in kidney transplant recipients increasing. Data on longitudinal ambulatory (ABP) trends pediatric young adult are limited. Retrospective review of a large cohort children adults following transplantation evaluation their ABP status over time associations with any patient clinical characteristics. Two hundred two patients had baseline ABPM available for analysis, 123 them follow up...
Hypertension is highly prevalent in pediatric kidney transplant recipients and contributes to cardiovascular death graft loss. Improper blood pressure (BP) measurement limits the ability control hypertension this population. Here, we report multicenter efforts from Improving Renal Outcomes Collaborative (IROC) standardize improve appropriate BP patients.Seventeen centers participated structured quality improvement activities facilitated by IROC, including formal training methods. The primary...
Secondary hyperparathyroidism (SHPT) is a rare complication of furosemide therapy that can occur in patients treated with the loop diuretic for long period time. We report 6-month-old 28-weeks premature infant chronically his bronchopulmonary dysplasia, who developed hypocalcemia and severe SHPT, adversely affecting bones. Discontinuation addition supplemental calcium calcitriol only partially reversed bringing serum parathyroid hormone level down from 553 to 238 pg/mL. After introduction...
Severe hypercalcemia in infants is usually attributed to genetic etiologies and less commonly acquired ones. An 8-week-old girl presented with failure thrive, mild respiratory distress, life-threatening (23.5 mg/dL). Serum 1,25(OH)2-vitamin D (1,25(OH)2-D) level was elevated parathyroid hormone undetectable. Evaluation for mutations malignant of negative. Treatment intravenous hydration, loop diuretic, calcitonin failed correct the hypercalcemia, which subsequently controlled bisphosphonate...
Background. Hemolytic uremic syndrome (HUS) is one of the common causes for acute kidney injury in childhood. Objective. The goals our study were to identify risk factors short-term complications and long-term outcomes chronic disease (CKD) Shiga toxin-producing Escherichia coli (STEC)-HUS other diarrhea positive (D+) HUS. Methods. Retrospective chart review was obtained 58 pediatric patients treated STEC-HUS D+ HUS between February 2002 January 2011. Results. Thirty-three (56.9%) required...
Abstract This case report discusses a pediatric patient who developed hemodialysis catheter line infection from an uncommon etiology, Mycobacterium fortuitum . The initial presentation revealed well appearing with slow growing skin lesion near the site of catheter. treatment course was complicated by resistance to antibiotics leading continued spread lesion. diagnosis confirmed via biopsy that required 2 weeks grow atypical Mycobacterium. Treatment successful after removal, transition...
Abstract Background and Aims Background: Poisonings, intoxications, drug overdoses are common occurrences rapid lowering of the toxin level is key all effective therapies. Therapeutic plasma exchange (TPE) has several unique characteristics that allow it to be a potentially therapy in rapidly achieving this goal with large molecular weight, protein-bound molecules have small volume distribution. Ibuprofen commonly used anti-inflammatory, antipyretic, analgesic drug. The number reported...
Background: COVID-19 has been associated with increased morbidity in kidney transplant recipients We aimed to identify risk factors for mortality hospitalized Methods: retrospectively reviewed the medical records of 75 admitted at our institution Results: Among patients, 28 (37%) died a median 8 days (range, 1-36) after admission hospital The Table summarizes demographics and initial labs values both groups Most patients were Hispanic (54%) African American (32%) 97% had hypertension 65%...