A5006160371- Adolescent and Pediatric Healthcare
- Blood Pressure and Hypertension Studies
- Renal Transplantation Outcomes and Treatments
- Dialysis and Renal Disease Management
- Medication Adherence and Compliance
- Organ Transplantation Techniques and Outcomes
- Patient-Provider Communication in Healthcare
- COVID-19 Clinical Research Studies
- Cardiovascular Syncope and Autonomic Disorders
- Childhood Cancer Survivors' Quality of Life
- COVID-19 Impact on Reproduction
- Bipolar Disorder and Treatment
- Mobile Health and mHealth Applications
- Behavioral Health and Interventions
- Renal and Vascular Pathologies
- Heart Rate Variability and Autonomic Control
- Parathyroid Disorders and Treatments
- Genetic and rare skin diseases.
- Cardiovascular Health and Risk Factors
- Patient Satisfaction in Healthcare
- Escherichia coli research studies
- Neurological Complications and Syndromes
- Adrenal and Paraganglionic Tumors
- Acute Myocardial Infarction Research
- Transplantation: Methods and Outcomes
Johns Hopkins University
2013-2024
Johns Hopkins Medicine
2016-2024
Johns Hopkins Children's Center
2023
Children's Hospital Association
2023
UC Davis Children's Hospital
2023
Johns Hopkins Hospital
2023
Allen (United States)
2022
Pediatric Nephrology of Alabama
2020
There are limited data on the impact of COVID-19 in children with a kidney transplant (KT). We conducted prospective cohort study through Improving Renal Outcomes Collaborative (IROC) to collect clinical outcome about pediatric KT patients. Twenty-two IROC centers that care for 2732 patients submitted testing and outcomes 281 tested SARS-CoV-2 by PCR. Testing indications included symptoms and/or potential exposures (N = 134, 47.7%) per hospital policy 154, 54.8%). Overall, 24 (8.5%)...
Abstract HLA eplet mismatch load has been suggested as an improvement to antigen determination for organ selection. Given that mismatches are determined based on amino acid sequence difference among alleles, and the frequency of alleles varies between racial groups, we investigated correlation allograft outcomes in 110 pediatric kidney transplant recipients who received their first from a donor same race (SRT) versus different (DRT). Adjusted modified Poisson regression was used assess...
The clinical manifestations of typical hemolytic uremic syndrome (HUS) encompass a wide spectrum. Despite the potentially severe sequelae from this syndrome, treatment approaches remain supportive. We present course child who contracted Shiga toxinpositive E. coli (STEC) daycare center during an outbreak. Utilizing modified Ham test which is rapid, serum-based functional assay used to detect activation alternative pathway complement as observed in atypical HUS, patient sera revealed evidence...
To investigate longitudinal associations of health beliefs, which included self-efficacy, outcome expectancies, and perceived barriers, demographic risk factors (i.e., age, gender, race, family income) with antihypertensive medication adherence in adolescents chronic kidney disease (CKD) over 24 months. The sample 114 (M age = 15.03 years, SD 2.44) diagnosed CKD. Adolescents reported their self-efficacy for taking medications, barriers to at baseline 12 months after baseline....
Hypertension is highly prevalent in pediatric kidney transplant recipients and contributes to cardiovascular death graft loss. Improper blood pressure (BP) measurement limits the ability control hypertension this population. Here, we report multicenter efforts from Improving Renal Outcomes Collaborative (IROC) standardize improve appropriate BP patients.Seventeen centers participated structured quality improvement activities facilitated by IROC, including formal training methods. The primary...
Up to one-third of adolescents and young adults (11-21 years old) with chronic kidney disease exhibit suboptimal rates adherence renal-protective antihypertensive medications. Mobile health interventions may promote higher these medicines in individuals, but empirical research is needed inform best practices for applying modalities.In this multiphase investigation, we developed tested a theoretically informed text messaging intervention based on the COM-B model, well-established framework...
Telemedicine interventions are being increasingly used in the care of adults with hypertension however application these technologies children high BP has not been systematically studied. The goal this project was to develop a mobile telemanagement system for and evaluate its feasibility. prototype consisted home unit, decision support server, management site. unit based on wireless netbook automated monitor. designed complete symptom diary, assess medication side effects, obtain BP, undergo...
Abstract It is well‐recognized that adolescence and early adulthood are a high‐risk period for non‐adherence with treatment regimens in solid organ transplant recipients, leading to high rates of rejection graft loss ( Transplantation , 92, 2011, 1237; Pediatr Transplant 9, 2005, 381; 77, 2004, 769). Preventing medication the holy grail adolescent care. If we can determine how best support our patients taking their daily medications as prescribed, improve long‐term health, reduce need...
Pediatric kidney transplant candidates often have multiple potential living donors (LDs); no evidence-based tool exists to compare LDs, or decide between marginal LDs and deceased donor (DD) transplantation (KT). We developed a pediatric profile index (P-LKDPI) on the same scale as DD KDPI by using Cox regression model risk of all-cause graft loss function characteristics KDPI. HLA-B mismatch (adjusted hazard ratio [aHR] per = 1.041.271.55), HLA-DR (aHR 1.021.231.49), ABO incompatibility...
Published data on LCP-tacrolimus (LCPT) in the pediatric population are limited.
The purpose of this study was to evaluate associations between executive functioning and caregiver adherence monitoring with objective antihypertensive medication over 24 months in adolescents chronic kidney disease (CKD).
Abstract Incontinentia pigmenti ( IP ) is an X‐linked dominant disorder that in most cases considered lethal males. affects the skin, hair, teeth, nails, eyes, and central nervous system. We report a case of persistent hypercalcemia (10.6–11.3 mg/ dL 19‐month‐old Caucasian boy with clinical . The proposed mechanism for his discussed.
<title>Abstract</title> Background Ambulatory Blood Pressure Monitoring (ABPM) is recommended for diagnosis and management of hypertension. We aimed to identify characteristics associated with physician action after receipt abnormal findings. Methods This was a retrospective cross-sectional analysis patients 5–22 years old who underwent 24-hr ABPM between 2003–2022, met criteria masked or ambulatory hypertension, had pediatric nephrology clinic visit within 2 weeks ABPM. “Action” defined as...
The original version of this article unfortunately contained a mistake. In the third paragraph “Discussion,” two references were missing.
Background: COVID-19 has been associated with increased morbidity in kidney transplant recipients We aimed to identify risk factors for mortality hospitalized Methods: retrospectively reviewed the medical records of 75 admitted at our institution Results: Among patients, 28 (37%) died a median 8 days (range, 1-36) after admission hospital The Table summarizes demographics and initial labs values both groups Most patients were Hispanic (54%) African American (32%) 97% had hypertension 65%...