A5067860713- Genetic diversity and population structure
- Genetic and phenotypic traits in livestock
- Aquaculture disease management and microbiota
- Fish Biology and Ecology Studies
- Fish Ecology and Management Studies
- Identification and Quantification in Food
- Aquaculture Nutrition and Growth
- Fish biology, ecology, and behavior
- Plant Pathogens and Fungal Diseases
- Genetic Mapping and Diversity in Plants and Animals
- Mycorrhizal Fungi and Plant Interactions
- Parasite Biology and Host Interactions
- Risk and Safety Analysis
- T-cell and B-cell Immunology
- Rabies epidemiology and control
- Genetic and Environmental Crop Studies
- Botanical Research and Applications
- Yeasts and Rust Fungi Studies
- Papaya Research and Applications
- Occupational Health and Safety Research
- Microbial Community Ecology and Physiology
- Poxvirus research and outbreaks
- Immunotherapy and Immune Responses
- CAR-T cell therapy research
- Plant Diversity and Evolution
University of Chile
2019-2024
Interdisciplinary Center for Aquaculture Research
2024
Catholic University of the Maule
2011-2018
Organisation Mondiale de la Santé Animale
2018
Fundación Ciencia and Vida
2018
Memory CD8+ T cell responses have the potential to mediate long-lasting protection against cancers. Resident memory (Trm) cells stably reside in non-lymphoid tissues and superior innate adaptive immunity pathogens. Emerging evidence indicates that Trm develop human solid cancers play a key role controlling tumor growth. However, specific contribution of anti-tumor is incompletely understood. Moreover, clinically applicable vaccination strategies efficiently establish remain largely...
For the first time, a morphometric characterization of chaura (Gaultheria pumila) fruits has been conducted between natural populations growing in Villarrica National Park, Araucania Region, Chile. Chaura is native Ericaceae from Chile that produces aromatic and tasty which could be agricultural interest. To influence decision for further domestication G. pumila, both fruit sizes (indicator productivity) nutritional properties have determined different subpopulations. Samples were total 74...
Abstract One of the main pathogens affecting rainbow trout (Oncorhynchus mykiss) farming is facultative intracellular bacteria Piscirickettsia salmonis. Current treatments, such as antibiotics and vaccines, have not had expected effectiveness in field conditions. Genetic improvement by means selection for resistance proposed a viable alternative control. Genomic information can be used to identify genomic regions associated with enhance genetic evaluation methods speed up trait. The...
Abstract Scarce genomic resources have limited the development of breeding programs for serrasalmid fish Colossoma macropomum (tambaqui) and Piaractus mesopotamicus (pacu), key native freshwater species produced in South America. The main objectives this study were to design a dense SNP array group validate its performance on farmed populations from several locations Using multiple approaches based different tambaqui pacu, final list 29,575 29,612 putative SNPs was selected, respectively,...
The impact of infectious disease may become progressively more harmful to a species' survival as wild population approaches an 'extinction vortex'. This risk is especially relevant for pathogens that spread rapidly and result in high mortality rates. Rabies, virus infects many mammalian species, can be efficiently transmitted through infected saliva, fatal without prior vaccination or rapid post-exposure prophylaxis (in humans). authors conducted extensive literature review identify all...
Sea lice (Caligus rogercresseyi) is an ectoparasite which causes major production losses in the salmon aquaculture industry worldwide. Atlantic (Salmo salar) and rainbow trout (Oncorhynchus mykiss) are two of most susceptible salmonid species to sea infestation. The objectives this study were to: (1) identify genomic regions associated with resistance Caligus rogercresseyi by performing single-step Genome-Wide Association studies (ssGWAS), (2) candidate genes related trait variation based on...
The characterization of runs homozygosity (ROH), using high-density single nucleotide polymorphisms (SNPs) allows inferences to be made about the past demographic history animal populations and genomic ROH has become a common approach characterize inbreeding. We aimed analyze patterns compare different pedigree-based methods estimate inbreeding coefficient in two pure lines (POP A B) one recently admixed line C) coho salmon (Oncorhynchus kisutch) breeding nuclei, genotyped 200 K Affymetrix...
Truffle (Tuber melanosporum Vitt.) culture is an agroforestry sector in Chile of increasing interest due to the high prices that truffles fetch national market and recent evidence its commercial production possible Chilean climatic soil conditions.In this study, efficiency three methods DNA extraction from a mix 5 g roots both nursery field plants Quercus ilex L. mycorrhized with T. were evaluated, simple reproducible protocol was established.Detection performed by technique cleaved...
Polymorphic microsatellite markers were developed for Gaultheria pumila (Ericaceae) to evaluate genetic diversity and population structure within its native range in Chile. This is a very important Ericaceae endemic Chile with large commercial potential. Its resistance different abiotic conditions makes it valuable target improvement.Ten polymorphic simple sequence repeat (SSR) loci isolated from using new-generation 454 FLX Titanium pyrosequencing technology. The mean number of alleles per...
Abstract Sea lice ( Caligus rogercresseyi ) are ectoparasites that cause major production losses in the salmon aquaculture industry worldwide. Atlantic Salmo salar and rainbow trout Oncorhynchus mykiss two of most susceptible salmonid species to sea infestation. The goal this study was identify common candidate genes involved resistance against lice. For this, 2,626 2,643 from breeding populations were challenged with genotyped a 50k 57k SNP panel. We ran independent genome-wide association...
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Pacu (Piaractus mesopotamicus) is one of the main native fish species for aquaculture in South America. Genomic selection essential developing desirable traits pacu production, but genotyping at high densities SNP markers can be costly producers. Cost-effective strategies involving genotype imputation facilitate broader adoption genomic this species. Then, objective study was to evaluate accuracies by adopting different (9 K, 7 5 2 1 and 0.5 K) from commercial Axiom® 30 K SerraSNP array...
Abstract Introduction We run a program for workers in the oil industry with “high risk COVID-19” aimed to identify presence of long-COVID and its impact on QOL follow up cases requiring additional diagnostic studies referral specialists. defined “High if had baseline factors (diabetes, overweight, respiratory, or cardiovascular diseases) complicated infections (pneumonia, oxygen requirement hospitalization). Methods identified throughout country COVID-19”. A special team doctors nurses,...
<title>Abstract</title> Flavobacterium oreochromis, is associated with high mortality rates in the early stages of tambaqui (Colossoma macropomum) production. This study investigated genetic effects caused by F. oreochromis infection juveniles comparing gene expression levels between symptomatic (IS) and asymptomatic (IA) individuals. A bacterial challenge was conducted intraperitoneal oreochromis. control group (CT) established where individuals were injected PBS. During challenge, 5 skin...
Efficient protocols for the extraction of microbial DNA from rhizosphere
Abstract Sea lice infestation is one of the major fish health problems during grow-out phase in Atlantic salmon ( Salmo salar ) aquaculture. In this study, we integrated different genomic approaches, including whole-genome sequencing (WGS), genotype imputation and meta-analysis genome-wide association studies (GWAS), to identify single-nucleotide polymorphisms (SNPs) associated with sea count salmon. Different sets trait-associated SNPs were prioritized compared against randomly chosen...
ABSTRACT One of the main pathogens affecting rainbow trout ( Oncorhynchus mykiss ) farming is facultative intracellular bacteria Piscirickettsia salmonis . Current treatments, such as antibiotics and vaccines, have not had expected effectiveness in field conditions. Genetic improvement by means selection for resistance proposed a viable alternative control. Genomic information can be used to identify genomic regions associated with enhance genetic evaluation methods speed up trait. The...
Abstract The characterization of runs homozygosity (ROH), using high-density single nucleotide polymorphisms (SNPs) allows inferences to be made about the past demographic history animal populations and genomic ROH has become a common approach characterize inbreeding. We aimed analyze patterns compare different pedigree-based methods estimate inbreeding coefficient in two pure lines (POP A B) one recently admixed line C) coho salmon breeding nuclei, genotyped 200K Affymetrix Axiom ® myDesign...