A5021555422- Medical and Biological Sciences
- Pharmacological Effects of Natural Compounds
- Pain Mechanisms and Treatments
- Innovations in Medical Education
- Technology and Human Factors in Education and Health
- Human Health and Disease
- Dermatology and Skin Diseases
- Healthcare Systems and Public Health
- Empathy and Medical Education
- Stress Responses and Cortisol
- Neurological Disorders and Treatments
- Fusion and Plasma Physics Studies
- Opinion Dynamics and Social Influence
- Ion channel regulation and function
- Neuroscience and Neuropharmacology Research
- Scientific Research and Philosophical Inquiry
- Pain Management and Opioid Use
- Mental Health Research Topics
- Foreign Language Teaching Methods
- Cholinesterase and Neurodegenerative Diseases
- Tryptophan and brain disorders
- Apelin-related biomedical research
- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Electroconvulsive Therapy Studies
First Pavlov State Medical University of St. Petersburg
2006-2024
Clinical Hospital No 122 named after. L.G.Sokolova
2020
Saint Petersburg State Pediatric Medical University
2019
Institute of Evolutionary Physiology and Biochemistry
2006-2017
Abstract Although the tricyclic antidepressant amitriptyline (ATL) is widely used in clinic, mechanism underlying its high therapeutic efficacy against neuropathic pain remains unclear. NMDA receptors (NMDARs) represent a target for ATL and are involved sensitization of pain. Here we describe two actions on NMDARs: 1) enhancement Ca 2+ -dependent desensitization 2) trapping channel block. Inhibition NMDARs by was found to be dependent upon external concentration ([Ca ]) voltage-independent...
Introduction. The English-language databases PubMed/MEDLINE and Embase are valuable information resources for finding original publications in basic clinical medicine. Currently, there no artificial intelligence systems to evaluate the quality of these publications. Aim. Development testing a system sentiment analysis (i.e. emotional modality) biomedical Materials methods. technique "Big data" was formulated on basis topological theory analysis. Algorithms have been developed that allow...
The state of human microbiome is closely related to higher nervous activity. Studies the relationship between and formation neuropsychiatric disorders represent a very promising field research. This work presents results comparative analysis profiles indicators in 36 ± 12-year-old patients with mental behavioral (n = 30) healthy volunteers 10). were measured on basis blood by mass chromatospectrometry. Numerous significant differences found patterns controls. On established differences, two...
Aim. To study the effectiveness of a virtual pharmacy as an element electronic information educational environment at Department Pharmacology. Material and methods. A total 250 3rd year students Faculty General Medicine 196 2nd Dentistry First Pavlov State Medical University St. Petersburg. achieve these goals, structured interviews, focus groups, subsequent analysis were used. The performance third-year was assessed before after introduction digital tools for visualizing material using...
Purpose: Review of methods for assessing cerebral energy exchange in order to select a method that has sufficient information content and good degree accessibility when examining nuclear industry workers. Results: To assess exchange, PET, SPECT, measurement local blood flow using isotope clearance are used. These techniques use the introduction radioactive substances into body. Their is limited by high cost equipment its stationary nature. Also, polarographic (invasive), REG fMRI provides...
Aim . To study the long-term knowledge retention in medical genetic disciplines and its reference to teaching format learning styles. Material methods Knowledge was assessed General Medicine students (n=63; men, 16%; women, 84%). The data obtained 4th year full-time 1st mixed (in-person distance) (retrospectively). by analyzing academic performance tests. Learning styles were studied using Styles Questionnaire (LSQ). Results When comparing biological person (Genetics 1) online (Parasitology...
To determine the efficacy of post-stroke dysphagia treatment by choline alfoscerate (ChA), succinate combination (SC), and their with sip, larynx, swallowing exercises.Four groups primary ischemic stroke (IS) patients (n=80; 62±0.2 y.o., verified MRI), including controls, admitted to Stroke Unit 24 h after in area RAM (29.5%), LAM (70.5%), were studied. Basic therapy was provided according National Treatment Recommendations, treated received ChA 14 mg/kg (2st gr.), SC 0.5 (3nd two compounds...
The article considers vocational and pedagogic position reflection as an important component of medical continuing education doctors. According to the general hypothesis study, a special program for training can contribute positively caregivers’ performance in treating patients, who experience troubles with compliance adaptation disease. key methods study include literature survey theoretical elaboration concept doctor reflection, meanwhile, empirical research is based on formative pilot...
The paper describes the features and components of academic course content teaching techniques aimed at forming pedagogic position (a set pedagogical knowledges, skills, competences, values, attitudes) a doctor in young resident physicians. This contributes to an effective health-oriented lifestyle dissemination adoption, especially patients with chronic diseases. It reflects new perception physician’s vocational duties, including care for patients’ life their need psychological support....
Aim. To assess the retention of theoretical knowledge internal medicine and practical skills in 6-year students Department General Medicine 5-6 months after exam. M aterial methods. Knowledge was assessed by testing on 11 topics (233 questions), while analyzed results electrocardiogram (ECG) interpretation clinical case task 48 students. Results . The following sections with a high very rate (average, 59,1%) were identified: gastroenterology hematology. One section low identified (emergency...
Aim. Analysis of the treatment response rates different therapy regimens functional constipation, including Ipidacrine, a cholinesterase inhibitor, based on assessment adaptation and compensatory mechanisms in forecast. Materials methods. 77 slow-transit constipation patients were examined after mean age is 44.30±14.58 y.o. Results discussion. The therapies with Ipidacrine depends patient's initial (ACM index); certain aspects allowing to predict expected result depending current mental...
The article describes the specifics of pedagogical training courses for residents and postgraduate students. Analysis regulatory documents scientific literature made it possible to assess activity a doctor, substantiate need its study in residency. vectors at Pavlov First Saint Petersburg State Medical University showed that program includes following vectors: development competencies work “school patients” psychological support process diagnosis, treatment, rehabilitation; ensuring...
Psychophysiological assessment of employees 10 Russian nuclear power plants revealed a low degree psychophysiological adaptation (PPA) in 30% subjects. Studying the fuctional activity (FA) brain by EEG decline FA individuals with PPA. The impaired cerebral energy exchange could be one factors contributing to functional state. study was aimed assess features hazardous facilities and productions A total 159 recordings acquired from PPA (50.8 ± 4.6), 152 high (48.8 1.5) were studied. Energy...
The authors have analyzed the results of City Psychosomatic Centre (CPSC) activity in 2009-2011 ys order to find out most important trends clinical work that may be helpful planning management and prophylaxis. methods applied were statistical clinico-statistical analyses Center ys. There changes structure by increasing incidence diseases associated with stress organic damage brain mental disorders, showed an increase flow male patients. Found average length stay bed center psychosomatic...
Purpose: Comparative assessment of the functional state and energy processes brain in workers nuclear hazardous enterprises industries with high low levels psychophysiological adaptation (PPA). The parameters spectral power EEG frequency ranges cerebral exchange at PPA, activity (FA) conditionally isolated structural formations (SFF) characterizing: mental level functioning − SFF-1, SFF-2, physiological SFF-3 were compared. Material methods: 311 archived – 159 individuals a PPA (50.8±4.6; 13...