A5063849431- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Infectious Aortic and Vascular Conditions
- Vascular Procedures and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Infective Endocarditis Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Orthopedic Infections and Treatments
- Protease and Inhibitor Mechanisms
- Abdominal Surgery and Complications
- Renal and Vascular Pathologies
- Cardiac Valve Diseases and Treatments
- Cardiac Arrest and Resuscitation
- Reconstructive Surgery and Microvascular Techniques
- Cardiovascular Health and Disease Prevention
- Acute Ischemic Stroke Management
- Central Venous Catheters and Hemodialysis
- Surgical Simulation and Training
- Surgical site infection prevention
- Hemodynamic Monitoring and Therapy
- Cell Adhesion Molecules Research
- Atherosclerosis and Cardiovascular Diseases
- Aortic Thrombus and Embolism
- Cardiac Structural Anomalies and Repair
University Hospital of Zurich
2015-2025
University of Zurich
2014-2024
Japanese Red Cross Narita Hospital
2022
Herzgefäss Medizin Klinik Im Park
2018
Research Center Borstel - Leibniz Lung Center
2018
German Center for Infection Research
2018
Kantonsspital Münsterlingen
2018
University of St. Gallen
2018
Kantonsspital Frauenfeld
2018
Ghent University Hospital
2017
Background— Mycotic aortic aneurysm (MAA) is a rare and life-threatening disease. The aim of this European multicenter collaboration was to study the durability endovascular repair (EVAR) MAA, by assessing late infection–related complications long-term survival. Methods Results— All EVAR treated MAAs, between 1999 2013 at 16 centers, were retrospectively reviewed. One hundred twenty-three patients with 130 MAAs identified. Mean age 69 years (range 39–86), 87 (71%) men, 58 (47%) had...
In Brief Objective: To evaluate a single center's 10-year experience with emergency endovascular aneurysm repair (eEVAR) in 102 patients ruptured abdominal aortoiliac aneurysms (RAAA). Methods: Data from (mean age, 73 ± 9 years) RAAA treated by eEVAR January 1998 to April 2008 were retrospectively reviewed. From 2000, all according an intention-to-treat protocol. The only exclusion criterion was unsuitable anatomy. 31/102 had moderate shock and 14/102 severe systolic blood pressure <70 mm Hg...
In Brief Objective: To present the combined 14-year experience of 2 university centers performing endovascular aneurysm repair (EVAR) on 100% noninfected ruptured abdominal aortic aneurysms (RAAA) over last 32 months. Background: Endovascular for RAAA feasibility is reported to be 20% 50%, and EVAR has been have better outcomes than open repair. Methods: We retrospectively analyzed prospectively gathered data 473 consecutive patients (Zurich, 295; Örebro, 178) from January 1, 1998, December...
To evaluate the performance of periscope and/or chimney grafts (CPGs) in endovascular treatment pararenal or thoracoabdominal aneurysms using off-the-shelf devices.Between February 2002 and August 2012, 77 consecutive patients (62 men; mean age 73±9 years) suffering from aortic (n=55), (n=16), arch to visceral artery (n=6) were treated with stent-graft implantation requiring maintain side branch perfusion. CPGs planned advance not used as bailout. A standardized follow-up protocol including...
To report midterm outcomes after urgent endovascular repair of ruptured pararenal or thoracoabdominal aortic aneurysms using multiple periscope and chimney grafts to preserve renovisceral branch perfusion facilitate aneurysm exclusion.Nine consecutive men (mean age 72±14 years, range 40-88) presenting with (n = 6), 2), infrarenal 1) underwent at least 1 graft delivered via a transfemoral access; were installed from an axillary access. In all, 17 7 used reperfuse 11 renal 13 visceral arteries...
Nuclear receptors and their cofactors regulate key pathophysiological processes in atherosclerosis development. The transcriptional activity of these nuclear is controlled by the receptor corepressors (NCOR), scaffolding proteins that form basis large corepressor complexes. Studies with primary macrophages demonstrated deletion Ncor1 increases expression atherosclerotic molecules. However, role atherogenesis unknown.We generated myeloid cell-specific knockout mice crossbred them low-density...
This article describes a new, less invasive prosthetic graft anastomotic technique that uses self-expanding stent grafts are “telescoped” into aortic branches. method, the VORTEC (Viabahn Open Revascularization TEChnique), obviates need for potentially difficult complete vessel exposure and anastomoses, thereby reducing duration of flow interruption simplifying performance complex reconstructions so-called debranching procedures requiring reconstruction major branches such as renal arteries....
Purpose:To present a technique for renal and visceral revascularization allowing complete endovascular treatment of ruptured type IV thoracoabdominal aneurysm using devices already stocked in most centers performing repair.Technique: Open arterial access is obtained to both common femoral arteries the left subclavian artery (LSA). Access through separate 8-F sheaths each branch. Both (celiac trunk superior mesenteric artery) are accessed 2 placed into LSA, artery. Corresponding covered...
PurposeTo present the 24-month radiological follow-up data for patients with pararenal aortic pathologies treated chimney and periscope grafts during endovascular repair.MethodsBetween January 2008 December 2011, 124 high-risk complex were using technique at 2 European vascular cardiovascular centers advanced experience of described technique. In particular, 50 Site 1 74 2. Forty (32.2%) (32 men; mean age 79.2±4.9 years) completed computed tomographic angiography 24 months...
The timely management of vascular graft/endograft infection (VGEI) is crucial to a favourable outcome, yet can be challenging as there no validated gold standard diagnostic test. Recently, new case definition has been proposed by the Management Aortic Graft Infection Collaboration (MAGIC) close gap. aim this study was validate MAGIC criteria suggested for diagnosis suspected VGEI in prospective Vascular Cohort (VASGRA).VASGRA an open, prospective, observational cohort study. Prospective...
In Brief Objective: To present the first long-term results of Szilagyi III vascular infections treated by negative pressure wound therapy (NPWT) with graft preservation. Background Data: are usually graft/artery excision and secondary vascular/plastic reconstruction. Small series NPWT without removal reported good short-term to midterm results. Methods: The outcomes 44 polymorbid patients (mean age = 62 years) from 2002 2009 were analyzed. Thirteen forty-four required intensive care unit...
In Brief Objectives: To present the safety, feasibility, costs, and patient satisfaction of outpatient endovascular aneurysm repair (EVAR). Background: Our experience in more than 1000 patients indicated that technically uncomplicated EVAR procedures, only need for hospitalization was access vessel complications (bleeding or occlusion) requiring secondary procedures. These could always be identified within first 3 hours after EVAR. Methods: Two-center retrospective analysis prospectively...
Folate receptor β (FR-β) is overexpressed on activated, but not resting, macrophages involved in a variety of inflammatory and autoimmune diseases. A pivotal step atherogenesis the subendothelial accumulation macrophages. In nascent lesions, they coordinate scavenging lipids cellular debris to define likelihood plaque inflammation eventually rupture. this study, we determined presence FR-β-expressing atherosclerotic lesions by use fluorine-18-labeled folate-based radiotracer. Human...
Research towards the non-invasive imaging of atherosclerotic plaques is high clinical priority as early recognition vulnerable may reduce incidence cardiovascular events. The fibroblast activation protein alpha (FAP) was recently proposed inflammation-induced protease involved in process plaque vulnerability. In this study, FAP mRNA and levels were investigated by quantitative polymerase chain reaction immunohistochemistry, respectively, human endarterectomized carotid plaques. A published...
Objective: To assess the effect of patient-specific virtual reality rehearsal (PsR) before endovascular infrarenal aneurysm repair (EVAR) on technical performance and procedural errors. Background: Endovascular procedures, including EVAR, are executed in a complex multidisciplinary environment, often treating high-risk patients. Consequently, this may lead to patient harm inefficiency. PsR enables team evaluate practice case environment real patient. Methods: A multicenter, prospective,...
To evaluate the midterm outcomes of chimney and/or periscope grafts (CPGs) in patients presenting type I endoleak after a previous endovascular aneurysm repair (EVAR).Between June 2002 and April 2014, 24 consecutive (mean age 73.9±9.2 years; 23 men) were addressed with CPGs to extend proximal distal landing zone maintain side branch perfusion. Indication for treatment was Ia (96%) Ib one. Median interval from EVAR 52.2±48.9 months (range 0.2-179). All had proximal/distal zones precluding any...