To investigate the process by which quercetin suppresses atherosclerosis upregulating MST1-mediated autophagy in RAW264.7 macrophages.An vitro foam cell model was established culturing macrophages with oxidized low-density lipoprotein (ox-LDL). The cells were treated alone or combination inhibitor, 3-methyladenine, and agonist, rapamycin. Cell viability detected a CCK-8 kit. Lipid accumulation oil red O staining, senescence SA-β-gal (senescence-associated β-galactosidase) reactive oxygen...

The copyrolysis and cocombustion behaviors of Pingshuo coal the biomasses (sawdust rice straw) have been investigated using a thermogravimetric analyzer. experimental results indicate that there exist synergetic effects between during their coconversion process. initial temperature volatile emission from corresponding to maximum conversion rate change with biomass mixture ratio. Moreover, it can be deduced comparison calculated DTG curves process is not sum conversion. During process, larger...

Preterm birth is a large-scale clinical problem involving over 10% of infants. Diagnostic means for timely risk assessment are lacking and the underlying physiological mechanisms unclear. To improve evaluation pregnancy before term, we introduce dedicated entropy measures derived from single-channel electrohysterogram (EHG).The estimation approximate (ApEn) sample (SampEn) adjusted to monitor variations in regularity EHG recordings, reflecting myoelectrical changes due progression. In...

In this paper, a novel processing framework is introduced for Fourier-domain beamforming of plane-wave ultrasound data, which incorporates coherent compounding and angular weighting in the Fourier domain. Angular implies spectral by 2-D steering-angle-dependent filtering template. The design filter also optimized as part paper. Two widely used methods, i.e., Lu's f-k Stolt's were integrated framework. To enable domain method, original method was modified to achieve alignment spectra...

Abstract The deformation and damage of soft rock roadways in karst mountainous area is serious, which greatly restricts the safe efficient mining coal resources. To explore instability mechanism roadway under influence mining, 226 rail cross-cut Shanjiaoshu Coal Mine China was taken as an engineering background. methods field monitoring drilling imaging were adopted to analyze failure characteristics. In addition, distributions plastic zone, surface displacement, fracture fractal evolution...

Due to its higher patency rate, a radial artery graft (RAG) is used as an interposition for internal-external high-flow bypass more frequently than saphenous vein (SAG). Nevertheless, there are still few cases of RAG stenosis after surgery. Unfortunately, these reports do not elaborate on the treatment stenosis. Here, we report first case severe STAt-RA-MCA bypass, which was successfully treated with PTA. We speculated that associated over-length and kinking intracranial segment instead...

As the sole cyanine dye approved by Food and Drug Administration (FDA), indocyanine green (ICG) has been widely applied in solid tumor metastases surgical navigation as well malignant tissue destruction. The great performance of ICG benefits from excellent fluorescent properties near infrared region (NIR) reactive oxygen species (ROS) or hyperthermia effects under irradiation. Nevertheless, some intrinsic limitations, such unstable optical properties, concentration-dependent aggregation,...

<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Objective:</i> Preterm birth is the leading cause of morbidity and mortality involving over 10% infants. Tools for timely diagnosis preterm are lacking underlying physiological mechanisms unclear. The aim present study to improve early assessment pregnancy progression by combining optimizing a large number electrohysterography (EHG) features with dedicated machine learning framework....

Abstract Investigation of nanobubble (NB) pharmacokinetics in contrast-enhanced ultrasound (CEUS) at the pixel level shows a unique phenomenon where first pass contrast agent bolus is accompanied by second wave. This effect has not been previously observed CEUS with microbubbles. The objective this study was to investigate second-wave and its potential clinical applications. Seven mice total fourteen subcutaneously-implanted tumors were included experiments. After injecting NBs, NB-CEUS...

Contrast-enhanced ultrasound (CEUS) by injection of microbubbles (MBs) has shown promise as a cost-effective imaging modality for prostate cancer (PCa) detection. More recently, nanobubbles (NBs) have been proposed novel contrast agents. Unlike MBs, which are intravascular agents, the smaller diameter NBs allows them to cross vessel wall and target specific receptors on cells such prostate-specific membrane antigen (PSMA). It demonstrated that PSMA-targeted can bind PCa show prolonged...

This study applies a recently developed model, LEACHV, to simulate transport of radon through unsaturated soil and compares calculated activities against field‐measured values. For volatile gas phase transport, LEACHV is modified from LEACHP, pesticide version LEACHM, well‐documented one‐dimensional model for water chemical movement soil. adds consideration air temperature changes flow driven by barometric pressure change the other variables currently used in LEACHP. It diurnal reflect more...

Coherent plane-wave compound imaging (CPWCI) is used as alternative for conventional focused (CFI) to increase frame rates linearly with the ratio number of lines steering angles. In this study, image quality was compared between CPWCI and CFI, effect angles (range number) beamforming strategies evaluated in CPWCI. automated breast volume scanners (ABVSs), which suffer from reduced rates, might be an excellent candidate replace CFI. Therefore, CFI currently ABVS also <italic...

Automated breast volume scanner (ABVS) is an ultrasound imaging modality used in cancer screening. It has high sensitivity but limited specificity as it hard to discriminate between benign and malignant lesions by echogenic properties. Specificity might be improved shear strain lesions, firmly bonded its host tissue, show different patterns compared often loosely bonded. Therefore, 3-D quasi-static elastography was implemented ABVS-like system. Plane wave instead of conventional focused...

Abstract Background The study is aimed to provide prediction for fertility risk in the setting of assisted reproduction a woman with complex chromosomal rearrangements (CCRs). Methods We implemented robust approach, which combined whole-genome low-coverage mate-pair sequencing (WGL-MPS), junction-spanning PCR and preimplantation genetic testing aneuploidy (PGT-A) method accurate chromosome breakpoint junctional sequences embryo selection process couple recurrent abortions due CCRs. Result...

The point spread function (PSF) is often analyzed to determine the image quality of an ultrasound system. formation PSF determined by practical factors, such as transducer aperture, element directivity, apodization, pitch, imaging position, and steering angle. Conventional numerical simulations provide iterative approach examine those factors' effects but cannot explain inherent mechanism formation. This article presents a theoretical approximation for plane-wave throughout Fourier-based...

The anterior communicating artery (AComA) complex is the site at which intracranial aneurysms occur most frequently. At present, effective treatments for AComA are yet to be developed. Here, we present our experience in successfully managing via transorbital keyhole approach. A total of 52 patients having a history aneurysm rupture received surgery. All were assigned Hunt-Hess grade prior cistern was opened expose using approach, and then surgically clipped with assistance neuroendoscopy or...

The magnet system is an important part in magnetic resonance imaging (MRI) equipment, the performance of which directly affects quality imaging. Improving homogeneity field effective means to increase signal-to-noise ratio (SNR). A high SNR ensures a good This paper mainly investigates optimal design and homogenizing analysis main for ferrite yoke flat-board type superconducting MRI using finite element method (FEM). In order get homogeneous field, pole piece added on pole. We use electric...

Quasi-static elastography is an ultrasound method which widely used to assess displacements and strain in tissue by correlating data at different levels of deformation. Ultrafast plane-wave imaging allows us obtain frame rates over 10 kHz, permitting the quantification visualization fast deformations. Currently, mainly three beam-forming strategies are reconstruct radio frequency (RF) from acquisitions: delay-and-sum (DaS), Lu’s-fk Stolt’s-fk operating temporal-spatial Fourier spaces,...

With a typical 100-500 nm diameter, nanobubbles are promising new-generation ultrasound contrast agent that paves ways for several applications, such as efficient drug delivery, molecular imaging, and assessment of vascular permeability. Due to their unique physical properties, exhibit distinct in vivo pharmacokinetics. We have shown the first pass nanobubble bolus is usually accompanied by appearance second (wave) within time range about 15 minutes. Such phenomenon, best our knowledge, has...