A5030590859- Structural Analysis and Optimization
- Genetics and Neurodevelopmental Disorders
- Autism Spectrum Disorder Research
- Fluid Dynamics Simulations and Interactions
- Topology Optimization in Engineering
- Family Support in Illness
- Composite Structure Analysis and Optimization
- Suicide and Self-Harm Studies
- Engineering Applied Research
- Cancer survivorship and care
- Schizophrenia research and treatment
- Vibration and Dynamic Analysis
- Genomic variations and chromosomal abnormalities
- Structural Load-Bearing Analysis
- Structural Engineering and Vibration Analysis
- Treatment of Major Depression
- Electroconvulsive Therapy Studies
- Sleep and related disorders
- Congenital heart defects research
- Cancer-related cognitive impairment studies
- Advanced Materials and Mechanics
- Music Therapy and Health
- Psychosomatic Disorders and Their Treatments
- Fluid Dynamics and Turbulent Flows
- Patient-Provider Communication in Healthcare
Tokai University
2016-2025
Nippon Sport Science University
2021-2025
Tokyo Institute of Technology
2024
Kyoto University
2023
Hong Kong Polytechnic University
2022
Utsunomiya University
2022
Fujian Normal University
2022
National Institute of Information and Communications Technology
2022
Whitney Museum of American Art
2022
Nayoro City General Hospital
2005-2021
Autism is a severe neurodevelopmental disorder of early childhood. Genetic factors play an important role in the aetiology disorder. In this study, we considered NRCAM gene as candidate autism. This expressed central nervous system and located 7q region, susceptibility locus We conducted case-control study 18 single nucleotide polymorphisms (SNPs) within for possible association with autism 170 autistic patients 214 normal controls Japanese population. Seven SNPs were significantly...
Background/Objectives: Volleyball training camps are known to reduce salivary secretory immunoglobulin A (s-SIgA); however, when it begins decrease is unclear. The validity of a simple device for quantifying s-SIgA lacking; hence, this study aimed observe detailed changes during volleyball camp after moving high altitude and investigate the difference in response between two quantification methods, namely, enzyme-linked immunosorbent assay (ELISA) lateral flow (LFD). Methods: Twenty-four...
This study aimed to investigate the circumstances, characteristics, and background factors of mental disorders within education learning-support services, which is known for frequent occurrence from overwork poor psychosocial work environment. The analyzed 119 cases suicides in services fiscal years 2010 2019 on database constructed by Japan Research Center Overwork-Related Disorders. results exhibit that cases, 56 (47.1%) involved male employees while 63 (52.9%) female employees. From 2019,...
Abstract Recently, two polymorphisms (DBH5′‐Ins/del and DBH 444 g/a) of the Dopamine Beta Hydroxylase (DBH) gene were isolated, one haplotype (Del‐a) was found to be associated with low activity cocaine‐induced paranoia. The purpose this study is test for association between these schizophrenia or its phenotypic variability respect neuroleptic therapeutic response symptom profile. Allelic distributions compared groups schizophrenic patients (excellent neuroleptic‐responders; R, n = 42...
Autism is a severe neurodevelopmental disorder with complex genetic aetiology. The wingless-type MMTV integration site family member 2 (WNT2) gene has been considered as candidate for autism. We conducted case-control study and followed up transmission disequilibrium test (TDT) analysis to confirm replication of the significant results first time. nine single nucleotide polymorphisms (SNPs) within WNT2 in 170 patients autism 214 normal controls Japanese population. then TDT 98 autistic...
Abstract The aim of this study was to determine the risk adverse events for risperidone and haloperidol in delirium patients. authors conducted a retrospective with medical records 266 Japanese inpatients who were referred them between July 2001 May 2005. Information on gender, age, delirium, drug therapy, events, death, other relevant factors collected analyzed each patient. As primary antipsychotic treatment used 93 patients; oral 95; intravenous or intramuscular 61. incidence 6.5%...
Marui T, Funatogawa I, Koishi S, Yamamoto K, Matsumoto H, Hashimoto O, Jinde Nishida Sugiyama Kasai Watanabe Kano Y, Kato N. The NADH‐ubiquinone oxidoreductase 1 alpha subcomplex 5 ( NDUFA5 ) gene variants are associated with autism. Objective: Autism appears to have a strong genetic component. product of the is included in mitochondrial electron transport chain. Method: We performed case–control study 235 patients autism and 214 controls examined three single‐nucleotide polymorphisms (SNPs)...
The purpose of this study was to examine the relationship between emotional suppression and psychological distress in breast cancer patients after surgery. We examined using questionnaires at first visit outpatient clinic our hospital surgery, as well interviews A total 31 were asked complete Courtauld Emotional Control Scale Profile Mood States their clinic. Patients also 1 6 months Trained clinical psychologists conducted interviews, asking speak freely about current anxieties, worries...
The nucleotide sequence of the uricase gene from thermophilic bacterium Bacillus sp. TB-90 was determined. primary structure deduced comprised 332 amino acids, with a total molecular mass 37,994 Da. subunit produced by transformant Escherichia coli agreed well this value. However, found to be 34,000 Da SDS-PAGE. difference between these masses attributed processing C-terminal 13 acid residue in TB-90. Comparison enzymatic properties both uricases showed that thennostability enhanced about...
The use of dantrolene sodium (DS) in the treatment neuroleptic malignant syndrome (NMS) was studied from data 21 cases NMS, which satisfied diagnostic criteria Pope et al . mean dosage DS 0.97 ± 0.52 mg/kg per day and duration 8.3 5.3 days. It confirmed that with tended to be longer involving disturbance consciousness. However, there were no significant differences or daily dosage, without consciousness regardless any other complications symptoms. Also, using between five considered...
Abstract Chromosome 15q11‐q13 has been a focus of genetic studies autism susceptibility, because cytogenetic abnormalities are frequently observed in this region autistic patients. An imprinted, maternally expressed gene within the may have role symptomatology. In present study, we investigated association between and maternal expression domain (MED) region, containing UBE3A ATP10C genes, upstream imprinting center (IC), which mediates coordinate control imprinted throughout region. We...
This paper attempts to apply reinforcement learning the structural morphogenesis problem of grid shells. The proposed method uses an autonomous decentralized system, which has low computational cost and high versatility because it does not require re-training when analysis model is changed. Iterative calculations on nodal neighborhood models are performed for analysis, Q-learning used learn shape modification rules that reduce external force work. Numerical examples show results agent...