A5101899858- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- MicroRNA in disease regulation
- Gut microbiota and health
- Pneumonia and Respiratory Infections
- Genomics and Phylogenetic Studies
- Sphingolipid Metabolism and Signaling
- Nitric Oxide and Endothelin Effects
- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Pain Mechanisms and Treatments
- PI3K/AKT/mTOR signaling in cancer
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pain Management and Placebo Effect
- GDF15 and Related Biomarkers
- Heart rate and cardiovascular health
- Fungal Infections and Studies
- Macrophage Migration Inhibitory Factor
- Nail Diseases and Treatments
- Antifungal resistance and susceptibility
- Nutrition and Health in Aging
- Hormonal and reproductive studies
- Peroxisome Proliferator-Activated Receptors
- Asthma and respiratory diseases
Jiaxing University
2018-2024
First Hospital of Jiaxing
2018-2021
Ibero American University
2021
There is a need for efficient, convenient, and inexpensive methods to accurately diagnose the clinical stage of lung cancer evaluate efficacy chemotherapy in patients with cancer. Although growth/differentiation factor 15 (GDF)-15 has great potential as tumor marker, supporting evidence still lacking. In this study, we aimed analyze relationship between serum GDF15 concentration characteristics cancer, assess value diagnosis curative effect chemotherapy.The study comprised 160 participants...
Background . Prognosis is a main factor affecting the survival of patients with lung adenocarcinoma (LUAD), yet no robust prognostic model high effectiveness has been developed. This study aimed at constructing stable and practicable gene signature-based via bioinformatics methods for predicting prognosis LUAD sufferers. Methods The mRNA expression data were accessed from TCGA-LUAD dataset, paired clinical information was collected GDC website. R package “edgeR” employed to select...
CerSs (ceramide synthases), a group of enzymes that catalyze the formation ceramides from sphingoid base and acyl-CoA substrates. As far, six types (CerS1-CerS6) have been found in mammals. Each these unique characteristics, but maybe more noteworthy is ability individual CerS isoform to produce ceramide with characteristic acyl chain distribution. key regulators sphingolipid metabolism, highlight their characteristics emerging roles regulating programmed cell death, cancer many other...
BackgroundThe most serious manifestation of pulmonary cryptococcosis is complicated with cryptococcal meningitis, while its clinical manifestations lack specificity delayed diagnosis and high mortality. The early prediction this complication can assist doctors to carry out interventions in time, thus improving the cure rate. This study aimed construct a nomogram predict risk meningitis patients through scoring system.MethodsThe data 525 were retrospectively analyzed, including 317 cases...
Abstract Neuropathic pain is the direct result caused by lesions or somatosensory nervous system diseases that are associated with emotional regulation. The incidence of neuropathic in general population 7-10% and mechanisms largely unknown. It often related to structural functional abnormalities multiple brain regions. forebrain, including nucleus accumbens (NAc), medial prefrontal cortex (mPFC) periaqueductal gray (PAG) have been shown correspond regulation pain. To investigate molecular...
Abstract Background The exact relation between smoking statuses and hypertension in the population with high-normal BP is poorly understood. Objective To investigate influence of various (active smoking, passive non-smoking) on resting heart rate blood pressure. Methods This was a cross-sectional study patients undergoing physical examination at three Chinese hospitals January 2018 December 2019, who conformed criteria BP. subjects were classified into non-smoking, active groups. (RHR)...
Abstract Background As mRNA binding proteins, MEX3 (muscle excess 3) family highlights its unique characteristics and plays an emerging role in post-transcriptionally regulating programmed of biological processes, including tumor cell death immunological relevance. These have been shown to be involved various diseases, however, the non-small-cell lung cancer (NSCLC) has not fully elucidated. Results In this study, we found that sequence or copy number gene did change significantly, which can...