A5011576296- Microbial Applications in Construction Materials
- Synthesis and biological activity
- Natural product bioactivities and synthesis
- Computational Drug Discovery Methods
- Phytochemistry and Biological Activities
- Cholinesterase and Neurodegenerative Diseases
- Horticultural and Viticultural Research
- Enzyme function and inhibition
- Phytochemistry and Bioactive Compounds
- Traditional and Medicinal Uses of Annonaceae
- Natural Antidiabetic Agents Studies
- Plant Pathogens and Fungal Diseases
- Phenothiazines and Benzothiazines Synthesis and Activities
- Fermentation and Sensory Analysis
- Yeasts and Rust Fungi Studies
- Bioactive Natural Diterpenoids Research
- Synthesis and Characterization of Heterocyclic Compounds
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Plant biochemistry and biosynthesis
- Medicinal Plants and Neuroprotection
- Click Chemistry and Applications
- Hepatitis C virus research
- Essential Oils and Antimicrobial Activity
- Silymarin and Mushroom Poisoning
Abdul Wali Khan University Mardan
2013-2025
Instituto Politécnico Nacional
2024
Pennsylvania State University
1999-2023
Bacha Khan University
2016
Centre National de la Recherche Scientifique
2012
Université de Picardie Jules Verne
2012
University of Karachi
2003-2011
International Center for Chemical and Biological Sciences
2003-2011
Fayetteville State University
2010
Cold Spring Harbor Laboratory
1996-1999
The yeast and human SKP1 genes regulate the mitotic cell cycle but are not yet known to be required for meiosis. Nine Arabidopsis homologues have been uncovered named ASK1 through ASK9 . Here, we report isolation characterization of a male sterile mutant show that defect was caused by Ds transposon insertion into gene. In ask1-1 mutant, abnormal microspores exhibit range sizes. Furthermore, during meiosis, although homologous chromosome pairing appeared normal at metaphase I, segregation...
Genetic linkage maps of Vitis (2n = 38) have been constructed from a single interspecific hybrid grape population (60 seedlings) 'Cayuga White' × 'Aurore'. The were primarily based on 422 RAPD markers but also included 16 RFLP and isozyme markers. These had an average distance 6.1 cM between developed using double-pseudotestcross strategy. map 214 covering 1196 that 'Aurore' spanned over 1477 with 225 consisted 20 groups, whereas 22 groups comprised the map. number reduced to 19, as in some...
Efficient functionalization of silicon substrates is important for the development silicon-based sensors. Organic monolayers directly bonded to hydrogen-terminated via Si–C bonds display enhanced stability toward hydrolytic cleavage. Here, we show that presenting a high density terminal azide groups are amenable bioconjugation with alkynyl-derivatized glycans copper-catalyzed azide–alkyne 1,3-dipolar cycloaddition. The prerequisite azide-functionalized surface fabricated hydrosilylation...
Different physical and chemical techniques are used for the decontamination of Cr+6 contaminated sites. The expensive, laborious, time-consuming. However, remediation by microbes is viable, efficient, cost-effective. In this context, plant growth-promoting rhizobacteria Acinetobacter bouvetii P1 isolated from industrial zone was tested its role in relieving induced oxidative stress sunflower. At elevated levels absence P1, growth sunflower plants inhibited. contrast, selected strain restored...
Two new diterpenoid alkaloids, heterophyllinine-A (1) and heterophyllinine-B (2), along with two known alkaloids dihydroatisine (3) lycoctonine (4) were isolated from the roots of Aconitum heterophyllum Wall. The structure deduced on basis spectral data. Compounds 1–2 inhibited acetylcholinesterase (AChE, EC 3.1.1.7) butyrylcholinesterase (BChE, 3.1.1.8) enzymes in a concentration-dependent manner percent inhibition ranging between 4.24% 6.94 % 79.1 82.75 for AChE BChE, respectively...
α-glucosidase (EC 3.2.1.20) is a primary carbohydrate metabolizing enzyme that acts on the 1-4 associated α-glucose residues. The inhibition of slows down process digestion and avoids postprandial hyperglycemia, which major cause chronic diabetes-associated complication. This study was designed to evaluate binding capacity isolated alkaloids with targetted receptor. For this purpose, three-dimensional tertiary structure α glucosidase generated by using MOE. model then validated RAMPAGE ERRAT...
The present study comprised of the synthesis dicyanoaniline derivatives pyridine, thiophene, furan, and substituted phenyl 1–29. All synthetic were evaluated for their potential to inhibit α-amylase α-glucosidase enzymes. synthesized compounds are classified into three categories A, B, C based on variable substituents at R1 R2, structure–activity relationship was discussed accordingly. Amongst twenty-nine derivatives, 1–29, five 2, 9, 18, 23, 24 displayed excellent inhibition against enzymes...
NS3/4A protease is an important emerging target for the cure of hepatitis C.There are many inhibitors HCV that passing through clinical improvement indicating momentous reduction in viral infection rate patients.In this study molecular docking via MOE-Dock program was used to evaluate binding interactions ligands with protease.The and experimental results were found good correlation.The best conformations analyzed residues cavity valuable scores observed compounds 01, 05, 06, 07, 08 09.
Three new diterpene esters with a myrsinol-type skeleton have been isolated from Euphorbia decipiens BOISS. & BUHSE. The structure elucidation of the compounds was based primarily on two-dimensional (2D)-NMR techniques including correlation spectroscopy (COSY), heteronuclear multiple quantum coherence (HMQC), bond (HMBC) and nuclear Overhauser effect (NOESY) experiments. Compounds 1 3 are active against prolyl endopeptidase compound 2 showed inhibitory activity urease enzyme.
During last decades, 3,5-disubstituted-tetrahydro-
The ethanolic extract derived from aerial parts of an indigenous medicinal plant Paeonia emodi was screened for enzyme inhibition activities against Urease (jack bean and Bacillus pasteurii) α-Chymotrypsin. also investigated its radical scavenging activity using DPPH assay. crude found to possess significant jack (74%) pasteurii (80%) urease a moderate (54%) displayed excellent (83%) activity. On the basis these results, subsequently fractionated into n-hexane, chloroform, ethyl acetate,...
A new flavonoid datisdirin (1), along with eight known compounds tectochrysine, cearoin, sideroxyline, ursolic acid, corosolic arjunolic erythrodiol and oleanolic were isolated from the ethyl acetate fraction of D. cannabina Linn. The structure compound 1 was deduced on basis its spectral data. Datisdirin showed activity against ureases enzyme.