A5057013347- Cannabis and Cannabinoid Research
- GABA and Rice Research
- Biochemical effects in animals
- Cardiac electrophysiology and arrhythmias
- Sphingolipid Metabolism and Signaling
- Pharmacological Effects of Medicinal Plants
- Neuroscience and Neuropharmacology Research
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Synthetic Organic Chemistry Methods
- Poisoning and overdose treatments
- Smoking Behavior and Cessation
- Lipid metabolism and biosynthesis
- Sesquiterpenes and Asteraceae Studies
- Plant biochemistry and biosynthesis
- Phytochemicals and Antioxidant Activities
- Biodiesel Production and Applications
- Phytochemical and Pharmacological Studies
- Psychedelics and Drug Studies
- Edible Oils Quality and Analysis
- Natural Antidiabetic Agents Studies
- Diet, Metabolism, and Disease
- Bone Metabolism and Diseases
- Asymmetric Synthesis and Catalysis
- Plant Toxicity and Pharmacological Properties
University of Szeged
2020-2024
Abstract The use of cannabidiol (CBD) in electronic cigarettes is widespread. Previously, it was reported that CBD partly transformed to THC case smoking as a cigarette, however, the pyrolysis this compound has not been assessed extensively. aim our study investigate effect temperature on composition products CBD. experiments were performed typical operating range e-cigarettes (250–400 °C) and at 500 °C under both inert oxidative conditions, identified quantified by GC–MS. Depending...
Abstract Cannabis use is associated with cardiovascular adverse effects ranging from arrhythmias to sudden cardiac death. The exact mechanism of action behind these activities unknown. aim our work was study the effect cannabidiol (CBD), tetrahydrocannabinol and 11-nor-9-carboxy-tetrahydrocannabinol on cellular electrophysiological properties including ECG parameters, potentials, hERG I Kr ion channels in HEK cell line rabbit guinea pig preparations. CBD increased potential duration right...
Abstract Cannabis use is associated with known cardiovascular side effects such as cardiac arrhythmias or even sudden death. The mechanisms behind these adverse are unknown. aim of the present work was to study cellular electrophysiological cannabidiol (CBD) on action potentials and several transmembrane potassium currents, rapid (I Kr ) slow Ks delayed rectifier, transient outward inward rectifier K1 currents in rabbit dog preparations. CBD increased potential duration (APD) significantly...
Introduction: The unmet need for highly effective, naturally derived products with minimal side effects results in the over-popularity of ever-newer medicinal plants. In middle 2010, containing cannabidiol (CBD), one special metabolites Cannabis sativa , started to gain popularity. For consumers and healthcare providers alike, legal context surrounding marketing CBD is not entirely clear, safety using some doubt. Companies online product market profit from confusion around oils. Methods: our...
ole-gum-resin extracts (BSEs) are commonly used as food supplements, especially in osteoarthritis management. The quality standard is established by determining 11-keto-β-boswellic acid (KBA) and acetyl-11-keto-boswellic (AKBA) content using high-performance liquid chromatography (HPLC) or assessing the total boswellic (TBA) titrimetry. limited geographical distribution of
Abstract Young shoots of cereals are widely regarded as superfoods with health benefits attributed to their potential antioxidant activity and antioxidant-related effects (e.g. anticancer). The current study aimed examine the chemical characteristics Hordeum vulgare methanolic aqueous extracts assess using DDPH ORAC. Furthermore, inhibitory effect xanthine oxidase was screened. TLC bioautography employed determine polarity compounds present in that exhibited most potent free radical...
Sesquiterpene lactones are specialized plant metabolites with promising pharmacological activities. These characteristic marker compounds for the aerial parts of
A library of pinane-based 2-amino-1,3-diols was synthesised in a stereoselective manner. Isopinocarveol prepared from (−)-α-pinene converted into condensed oxazolidin-2-one two steps by carbamate formation followed aminohydroxylation process. The relative stereochemistry the pinane-fused determined 2D NMR and X-ray spectroscopic techniques. regioisomeric spiro-oxazolidin-2-one similar way starting commercially available (1 R )-(−)-myrtenol ( 10 ). reduction or alkaline hydrolysis...
A library of pinane-based 2-amino-1,3-diols, analogues biologically active sphingosine, was synthesised in a stereoselective manner. Isopinocarveol prepared from (–)-α-pinene converted to condensed oxazolidin-2-one two steps by carbamate formation followed aminohydroxylation process. The relative stereochemistry the pinane-fused determined 2D NMR and X-ray technics. regioisomeric spiro-oxazolidin-2-one similar way starting commercially available (1 R )-(–)-myrtenol. Reduction or alkaline...
The use of cannabis and cannabinoids are mainly reserved for medical application; however, the regulation in some countries has decriminalised recreational these. Furthermore, Cannabis CBD can be found edibles, as well. These edibles available dedicated food stores, more accessible online. Although, parts hemp used ingredients with limitation on THC content (< 0.2 – 0.3%), extract have not been traditionally.
Cannabidiol (CBD) has become one of the most popular natural compound applied in various different ways. Although, it evidence based medical application (i.e., Epidiolex® for seizure disorder), indications widely available CBD-containing food supplements are mostly not supported. Furthermore, frequent or long-term cannabidiol without supervision been investigated. Finally, loose and uncontrolled legal environment regulating market, Cannabis products CBD-content is controlled by National...
The issue of Cannabis sativa affected numerous fields research and has provided space for valuable possibilities.Its importance as a remedy is unquestionably getting popular nowadays.Due to the unclear legislation, consumers have access cannabis-containing food supplements in shops through online websites.Uncontrolled authorisation procedures contribute potential health risk factors these products.The main goal our work was investigate cannabis oil available on market.We developed several...