A5100733146- Food Quality and Safety Studies
- Meat and Animal Product Quality
- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Nutrition, Health and Food Behavior
- Quantum Chromodynamics and Particle Interactions
- Vector-borne infectious diseases
- Insect and Pesticide Research
- Animal Nutrition and Physiology
- Insect symbiosis and bacterial influences
- Neurobiology and Insect Physiology Research
- Agriculture, Soil, Plant Science
- Genetic and phenotypic traits in livestock
- Mosquito-borne diseases and control
- Insect and Arachnid Ecology and Behavior
- Probiotics and Fermented Foods
- Insect Utilization and Effects
- Groundwater and Isotope Geochemistry
- Viral Infections and Vectors
- Mycorrhizal Fungi and Plant Interactions
- Plant Virus Research Studies
- Groundwater flow and contamination studies
- Insect-Plant Interactions and Control
- Non-Destructive Testing Techniques
- Hydrology and Watershed Management Studies
Kyungpook National University
2015-2025
Korea Institute of Geoscience and Mineral Resources
2018-2023
Center for Disease Dynamics, Economics & Policy
2021-2023
Pennsylvania State University
2018-2023
Seoul National University Hospital
2022
Kansas State University
2013-2021
Waters (United States)
2014-2018
Michigan State University
2018
Entomological Society of America
2016
Yonsei University
2010-2014
Abstract Ticks transmit more pathogens to humans and animals than any other arthropod. We describe the 2.1 Gbp nuclear genome of tick, Ixodes scapularis (Say), which vectors that cause Lyme disease, human granulocytic anaplasmosis, babesiosis diseases. The large reflects accumulation repetitive DNA, new lineages retro-transposons, gene architecture patterns resembling ancient metazoans rather pancrustaceans. Annotation scaffolds representing ∼57% genome, reveals 20,486 protein-coding genes...
Abstract Cas9-mediated gene editing is a powerful tool for addressing research questions in arthropods. Current approaches rely upon delivering Cas9 ribonucleoprotein (RNP) complex by embryonic microinjection, which challenging, limited to small number of species, and inefficient even optimized taxa. Here we develop technology termed Receptor-Mediated Ovary Transduction Cargo (ReMOT Control) deliver RNP the arthropod germline injection into adult female mosquitoes. We identify peptide (P2C)...
Bifidobacterium longum strains predominate in the colonic microbiota of breast-fed infants. Here we report complete genome sequence B. subsp. KACC 91563, isolated from feces neonates. A single circular chromosome 2,385,301 bp contains 1,980 protein-coding genes, 56 tRNA and 3 rRNA operons.
Despite their capacity to acquire and pass on an array of debilitating pathogens, research ticks has lagged behind other arthropod vectors, such as mosquitoes, largely because challenges in applying available genetic molecular tools. CRISPR-Cas9 is transforming non-model organism research; however, successful gene editing not yet been reported ticks. Technical for injecting tick embryos attempt have further slowed progress. Currently, no embryo injection protocol exists any chelicerate...
Summary Herbivore‐induced plant volatiles (HIPVs) are widely recognized as an ecologically important defensive response of plants against herbivory. Although the induction this ‘cry for help’ has been well documented, only a few studies have investigated inhibition HIPVs by herbivores and little is known about whether evolved mechanisms to inhibit release HIPVs. To examine role herbivore effectors in modulating stomatal dynamics, we conducted series experiments combining pharmacological,...
In the postgenomics era, comparative genomics have advanced understanding of evolutionary processes neuropeptidergic signaling systems. The origin many systems can be traced date back to early metazoan evolution based on conserved sequences. Insect parathyroid hormone receptor (iPTHR) was previously described as an ortholog vertebrate PTHR that has a well-known function in controlling bone remodeling. However, there no sequence homologous PTH insect genomes, leaving iPTHR orphan receptor....
Ticks are important ectoparasites and vectors of numerous human animal pathogens. secrete saliva that contains various bioactive materials to evade the host defense system, often facilitates pathogen transmission. In addition, Lone star tick is thought be sensitizer in red meat allergy characterized by an allergic reaction glycan moieties carrying terminal galactose-alpha-1,3-galactose (aGal). To assess N-glycome Amblyomma americanum, we examined N-glycan structures male female salivary...
ABSTRACT The small brown planthopper, Laodelphax striatellus , is a major pest and the primary vector of rice stripe virus, harmful pathogen that significantly affects production across East Asia. This study aims to investigate effects different temperatures (24°C, 27°C, 30°C) on developmental period, virus infection rates, transmission efficiency planthopper at various stages. Higher shortened period planthopper. time from egg adult was approximately 5 days shorter 30°C than 24°C. rate...
Expression of the Vir2 gene Cryphonectria parasitica is down-regulated in strains fungus containing a double-stranded RNA genetic element that reduces fungal virulence (W. A. Powell and N. K. Van Alfen, Mol. Cell. Biol. 7:3688-3693, 1987). We have sequenced characterized its structure; mRNA contains short open reading frame whose product has structural similarities to several pheromones. A null mutant was constructed by homologous recombination determine function whether disruption resulted...
Control of salivary secretion in ticks involves autocrine dopamine activating two receptors: D1 and Invertebrate-specific D1-like receptors. In this study, we investigated Na/K-ATPase as an important component the secretory process. Immunoreactivity for revealed basal infolding lamellate cells type-I, abluminal interstitial (epithelial) type-II, labyrinth-like structures opening towards lumen type-III acini. Ouabain (10 μmol l(-1)), a specific inhibitor Na/K-ATPase, abolished...
Globalization and climate change have contributed to the simultaneous increase spread of arboviral diseases. Cocirculation several arboviruses in same geographic region provides an impetus study impacts multiple concurrent infections within individual vector mosquito. Here, we describe coinfection superinfection with Mayaro virus (Togaviridae, Alphavirus) Zika (Flaviviridae, Flavivirus) vertebrate mosquito cells, as well Aedes aegypti adult mosquitoes, understand interaction dynamics these...
The control of tick salivary secretion, which plays a crucial role in compromising the host immune system, involves complex neural mechanisms. Dopamine is known to be most potent activator as paracrine/autocrine factor. We describe invertebrate-specific D1-like dopamine receptor (InvD1L), highly expressed glands. InvD1L phylogenic clade was found only invertebrates, suggesting that this lost vertebrates during evolution. Chinese hamster ovary (CHO)-K1 cells activated by with median effective...
Salivary secretion is crucial for successful tick feeding, and it the mediator of pathogen transmission. Salivation functions to inhibit various components host immune system remove excess water ions during ingestion large blood meals. Control salivary glands involves autocrine/paracrine dopamine, which most potent inducer salivation. Previously, we reported presence two dopamine receptors in blacklegged (Ixodes scapularis): receptor (D1) invertebrate specific D1-like (InvD1L). Here,...
Riparian zones with their buffering ability and abundant water supply are often subjected to intensive agricultural activities. We investigated a riparian aquifer located near stream in South Korea that recently experienced sharply decreasing groundwater levels elevated nitrate (NO3-) concentrations, which were attributed local Our goal was identify the predominant nitrogen sources NO3- removal processes. Multiple approaches including geochemical isotopic tracers, land-use analysis,...
본 연구는 수소 및 거세우(24-30개월) 15두(각 육질등급별 3두씩)를 공시축으로 이용하여 우육의 부위(목심, 채끝, 우둔, 양지머리, 등심)에 따른 육질등급(<TEX>$1^{++}$</TEX>, <TEX>$1^+$</TEX>, 1, 2, 3)별 일반성분, pH, 육색, 보수력, 가열감량, 콜레스테롤 트랜스지방산 함량을 조사하였다. 일반성분에서 단백질함량은 16.66-22.64% 범위고 수분함량은 57.40-75.69% 범위 였으며 지방함량은 0.61-24.74%로 나타났다. <TEX>$1^{++}$</TEX>등급 목심, 등심부위가 16.66-19.26%범위로 유의적으로 낮은 나타난 반면에 3등급에서는 21.50-22.48%로 높게 나타났다(p<0.05). 3등급이 다른 육질등급에 비해 낮게 pH는 5.49-5.88범위로 <TEX>$1^+$</TEX>등급 목심(5.61)과 채끝(5.51)이 3등급 목심(5.88), 채끝(5.92)부위보다 우둔과 양지머리 등심부위에서는...
The effective management of endangered animal genetic resources is one the most important concerns modern breeding. Evaluation diversity and relationship local breeds an factor towards identification unique valuable resources. This study aimed to analyze population structure six Korean native chicken (n = 300), which were compared with three imported in Korea 150). For analysis diversity, 30 microsatellite markers from FAO/ISAG recommended panel or previously reported used. number alleles...
Tick salivary glands play critical roles in maintaining water balance for survival, as they eliminate excess and ions during blood feeding on hosts. In the long duration of fasting off-host period, ticks secrete hygroscopic saliva into mouth cavity to uptake atmospheric vapor. Type I acini tick are speculated be involved secretion based ultrastructure studies. However, we recently proposed that type a role resorption water/ions from primary produced by other (i.e., types II III) phase. this...
Recent studies have provided strong evidence indicating that lone star tick bites are a cause of AGS (alpha-gal syndrome, also known as red meat allergy RMA) in humans. is characterized by an increase IgE antibody production against galactose-alpha-1,3-galactose (aGal), which common glycan found mammalian tissue, except Old World monkeys and The main causative factor AGS, the (Amblyomma americanum), broadly distributed throughout east midwest United States vector wide range human animal...
본 연구는 국내에서 최고의 고급육으로 유통되는 한우고기의 부위별 성분조성 및 육질특성을 조사하고자 <TEX>$1^{++}$</TEX> 육질등급을 받은 거세한우 10두에서 10부위(업진, 보섭, 채끝, 등심, 꾸리, 홍두깨, 목심, 설깃, 양지, 우둔)를 선정하여 분석하였다. 10부위간에 칼로리 함량은 <TEX>$2,205{\sim}3713.20\;cal/g$</TEX> 범위였으며 특히 채끝 업진부위가 다른 부위들과 비교하여 유의적으로 높은 것으로 나타났다(p<0.05). 콜레스테롤 함량도 <TEX>$38.86{\sim}44.69\;mg/100g$</TEX> 수준으로 10부위 중에서 목심부위가 가장 높았고 홍두깨와 우둔부위가 부위와 낮은 분석되었다(p<0.05). 가용성 불용성 콜라겐 함량에 있어서는 부위별로 유의적인 차이가 없었으나 총 목심 설깃부위가 등심 채끝부위가 맛과 관련이 있는 유리아미노산함량을 비교한 결과 모든 부위에 glutamate와 alanine 함량이 각각...
본 연구는 수소 및 거세우(24-30개월) 15두(각 육질등급별 3두씩)를 공시 축으로 이용하여 한우육의 부위(목심, 채끝, 우둔, 양지머리, 등심)에 따른 육질등급(<TEX>$1^{++}$</TEX>, <TEX>$1^+$</TEX>, 1, 2, 3)의 지방산 조성을 비교하였다. 조성에서 C16:0 함량은 목심, 채끝과 우둔부위 3등급이 다른 등급보다 유의적으로 높았던 반면 양지머리와 등심부위에서는 2등급이 각각 28.26%, 28.74%로 3등급 26.16%, 25.30%보다 높게 나타났다(p<0.05). C18:1n9 목심 부위에서는 유의적인 차이가 나타나지 않았지만 <TEX>$1^{++}$</TEX>등급이 3등급보다 C18:3n3 우둔과 않았고 양지머리부위에서 0.15%로 높았는데 0.23%로 C18:3n6 목심과 등심부위에서만 나타났는데 높았다(p<0.05). SFA 다섯 부위에서 <TEX>$1^{++}$</TEX> 등급이 낮은 반면에 MUFA 나타났고(p<0.05)...