A5101762122- Kidney Stones and Urolithiasis Treatments
- Pediatric Urology and Nephrology Studies
- Ureteral procedures and complications
- Nitric Oxide and Endothelin Effects
- Renal and Vascular Pathologies
- Lung Cancer Treatments and Mutations
- Blood Pressure and Hypertension Studies
- Renin-Angiotensin System Studies
- HER2/EGFR in Cancer Research
- Abdominal Surgery and Complications
- Dialysis and Renal Disease Management
- Renal function and acid-base balance
- Sexual Differentiation and Disorders
- Traumatic Ocular and Foreign Body Injuries
- Brain Metastases and Treatment
- Urinary Bladder and Prostate Research
- Cell death mechanisms and regulation
- Cannabis and Cannabinoid Research
- Neuroscience and Neuropharmacology Research
- Medical Imaging Techniques and Applications
- Neurological Disease Mechanisms and Treatments
- Glaucoma and retinal disorders
- Ferroptosis and cancer prognosis
- Machine Learning in Healthcare
- Digital Imaging in Medicine
Ganzhou People's Hospital
2014-2025
Nanchang University
2014-2024
Southern Medical University
2018-2024
Nanfang Hospital
2018-2024
Huazhong University of Science and Technology
2022-2023
Union Hospital
2023
Shanghai Stomatological Hospital
2023
Jiangjin Central Hospital
2015
ShenZhen People’s Hospital
2014
Chongqing Medical University
2013
Early-life exposure to environmental stress disrupts the gut barrier and leads inflammatory responses changes in microbiota composition. Gallic acid (GA), a natural plant polyphenol, has received significant interest for its antioxidant, anti-inflammatory, antimicrobial properties that support maintenance of intestinal health. To assess whether dietary supplementation GA alleviates stress, total 19 puppies were randomly allocated following three treatments 2 weeks: 1) basal diet (control...
Background: Flexible ureteroscopic lithotripsy (URS) is rapidly becoming a first-line therapy for patients with renal and ureteral calculi. Most current medical infusion devices can only monitor flow pressure, but not pelvic pressure (RPP). Patients Methods: We designed patented intelligent system to facilitate flexible URS that included an irrigation suctioning platform access sheath (UAS) pressure-sensitive tip, enabling regulation of the precisely control vacuum by computerized real-time...
Introduction: The aim of this study was to evaluate the safety and efficacy flexible ureteroscopy using a tip-flexible pressure-controlling ureteral access sheath (TFPC-UAS) for renal stones in children. Methods: Consecutive patients aged 5–18 years with diameter 1–3 cm were enrolled between January 2022 November 2023 at Ganzhou People’s Hospital. treated TFPC-UAS. pelvic pressure (RPP) parameters set as follows: control value −10 mm Hg 5 Hg, warning 20 limit 30 Hg. infusion flow rate...
Electroacupuncture (EA) performed in rats and humans using limb acupuncture sites, LI-4 LI-11, GV-14 GV-20 (humans) Bai-hui (rats) increased functional connectivity between the anterior hypothalamus amygdala mobilized mesenchymal stem cells (MSCs) into systemic circulation. In human subjects, source of MSC was found to be primarily adipose tissue, whereas rodents tissue sources were considered more heterogeneous. Pharmacological disinhibition rat enhanced sympathetic nervous system (SNS)...
Globally, bladder cancer is the tenth most common cancer. Mitophagy, a critical process regulating mitochondrial quantity and quality, has attracted increasing attention for its pivotal function in Nonetheless, roles underlying mechanisms are yet to be elucidated. Therefore, this study, 16 mitophagy-related genes were screened construct robust prognostic model with exceptional predictive accuracy outcomes of patients Of these genes, DARS2 was identified as key regulator that significantly...
Abstract Short-term infusions of angiotensin II (Ang II) increase renal vascular resistance and thereby endothelial shear stress nitric oxide (NO) release. Prolonged stimulation Ang can decrease the expression NO synthase isoforms in macula densa, but prolonged increases transcription synthase. Therefore, we designed these studies to test hypothesis that exerts time-dependent effects on generation as assessed from excretion nitrate nitrite, percent during inhibition with intravenous N G...
Since dietary salt loading enhances nitric oxide (NO) generation in the kidney, we investigated hypothesis that changes intake have specific effects on vascular resistance kidney mediated by L-arginine-NO pathway. We contrasted renal and hindquarter resistances (RVR HQVR) anesthetized rats during intravenous infusions of graded doses NO synthase inhibitor NG-nitro-L-arginine methyl ester (L-NAME). Groups (N = 8 to 10) were maintained a high (HS) or low (LS) diet for two weeks. Compared those...
Micropuncture studies of single nephrons have shown that macula densa solute reabsorption via a furosemide-sensitive pathway activates nitric oxide (NO) generation neuronal NO synthase (nNOS). This is enhanced during salt loading. We investigated the hypothesis changes in nNOS contribute to whole kidney and action alterations intake. Groups rats ( n = 6–10) were equilibrated high-salt (HS) or low-salt (LS) diets administered vehicle (Veh), 7-nitroindazole (7-NI; relatively selective...
This study validates the accuracy of miniature ultrasonic transit-time flow probes for measuring renal blood (RBF) in rat. Probes 1-mm and 2-mm vessels were calibrated ex vivo using excised arteries at varying rates hematocrit (Hct). Correlation between measured true probe identical (r = 1.0) both normal subnormal Hct values. was high 0.994) Hct, but varied In correlation RBF measurements with clearance extraction p-aminohippuric acid showed a 0.84; n 72, P < 0.0001) over wide range...
In order to better control renal pelvic pressure (RPP), reduce surgical complications and increase operative efficacy of minimally invasive percutaneous nephrolithotomy (MPCNL), we designed an MPCNL with intelligent monitoring RPP sought explore its clinical characteristics.This study included 60 patients staghorn calculi. A 5F ureteral catheter was connected blood monitor for RPP. 12F renoscope inserted through a tract lithotripsy using laser, the help system continuously, which includes...
<b><i>Objectives:</i></b> To investigate the safety, efficacy, and practicability of minimally invasive percutaneous nephrolithotomy (MPCNL) with aid a patented irrigation clearance system in treating renal staghorn calculi. <b><i>Methods:</i></b> From August 2009 to July 2014, 4 hospitals had executed prospective multicenter study total 912 cases. The patients were randomly divided into 3 groups: suctioning MPCNL, standard (PCNL), traditional...
The aim of the study was to compare treatment outcomes between suctioning flexible ureteroscopic lithotomy (SF-URL) with automatic control renal pelvic pressure and minimally invasive percutaneous nephrolithotomy (MPCNL) for management 2-3-cm stones in patients a solitary kidney.A total 127 kidney who underwent SF-URL (n = 57) or MPCNL 70) large (>2 cm) June 2015 October 2020 were consecutively analyzed. stone characteristics, operative times, stone-free rate (SFR), hospital stays,...
The purpose of the study was to evaluate efficacy and safety a patented perfusion suctioning platform ureteral access sheath in treatment large stones (≥ 1.5 cm) below L4 level.We recruited 122 patients with level at our hospital from December 2014 June 2017. were randomly divided into control groups. Multiple operative perioperative parameters compared between two groups.The group had shorter operation time, less cases postoperative fever, lower serum levels PCT, IL-6 BET within 24 h after...
Infusion of L-arginine, the substrate for nitric oxide synthase, causes renal vasodilation. Since dietary salt restriction blunts vasoconstrictor response to inhibition we investigated hypothesis that intake determines vascular L-arginine. Bolus intravenous doses L-arginine given anesthetized Sprague-Dawley rats caused dose-dependent increases in blood flow and decreases resistance, whereas D-arginine was not effective. The prevented by pretreatment with NG-nitro-L-arginine methyl ester....
Abstract Objective To evaluate the safety and efficacy of rigid ureteroscopic lithotripsy with a pressure-controlling ureteral access sheath (PC-UAS) for complex steinstrasse. Methods Thirty-one consecutive patients (male: 18; female: 13) steinstrasse were enrolled, six whom had concurrent kidney stones. The mean cumulative stone size was 2.7 ± 1.3 cm. treated using PC-UAS. cavity pressure parameters set as follows: control value at -15 mmHg to -2 mmHg, warning 20 limit 30 mmHg. infusion...
Flexible ureteroscopy is very valuable for treating upper urinary tract calculi. However, no report has yet compared the clinical outcomes of flexible performed on patients in different body positions. Therefore, we safety and efficacy suctioning ureteroscopic lithotripsy with automatic control renal pelvic pressure oblique supine lithotomy position position.A total 82 kidney calculi by were retrospectively analyzed single center. Group 1 included 47 treated via position. 2 35 There...