A5105841644- CAR-T cell therapy research
- Hormonal and reproductive studies
- Pancreatic and Hepatic Oncology Research
- Sexual function and dysfunction studies
- Pharmacology and Obesity Treatment
- Ecology and Vegetation Dynamics Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Galectins and Cancer Biology
- Virus-based gene therapy research
- Sexual Differentiation and Disorders
- Plant biochemistry and biosynthesis
- Inflammatory Biomarkers in Disease Prognosis
- Ovarian function and disorders
- Plant Ecology and Soil Science
- Gallbladder and Bile Duct Disorders
- Cancer Cells and Metastasis
- Adipokines, Inflammation, and Metabolic Diseases
- Glycosylation and Glycoproteins Research
- Reproductive Health and Technologies
- Plant Water Relations and Carbon Dynamics
- Evacuation and Crowd Dynamics
- Banana Cultivation and Research
- Pancreatitis Pathology and Treatment
- Muscle metabolism and nutrition
- PI3K/AKT/mTOR signaling in cancer
The First People's Hospital of Changzhou
2024-2025
Soochow University
2017-2025
Gansu Agricultural University
2024
Dali University
2023
Dalian Medical University
2018-2023
First Affiliated Hospital of Dalian Medical University
2023
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2023
Wenzhou Medical University
2023
Jiangnan University
2022
Institute of Botany
2021
Chimeric antigen receptor (CAR) T-cell therapy targeting CD19 may be associated with long-term adverse effects such as cytopenia and immune deficiency. In order to characterize these late events, we analyzed 31 patients relapsed or refractory large B-cell lymphoma treated axicabtagene ciloleucel at our institution on two clinical trials, ZUMA-1 (clinicaltrials gov. Identifier: NCT02348216) ZUMA-9 NCT03153462). Complete blood counts, lymphocyte subsets, immunoglobulin levels were measured...
Metabolic health is closely related to testosterone levels, and the cardiometabolic index (CMI) a novel metabolic evaluation metric that encompasses obesity lipid metabolism. However, there currently lack of research on relationship between CMI testosterone, which objective this study. This study utilized data from National Health Nutrition Examination Survey (NHANES) cycles 2011 2016. Only adult males who completed physical measurements, metabolism assessments, measurements were included in...
Overactive bladder (OAB) and female sexual dysfunction (FSD) are both common problems in women, but the association between OAB FSD lacks a large sample study. The purpose of this cross-sectional study was to investigate FSD. Data for were obtained from 2007–2016 National Health Nutrition Examination Survey (NHANES) women aged 20–59 years. qualified with aid overactive symptom score (OABSS), which by adding nocturia urge urinary incontinence score, participants total ≥ 3 considered suffer...
To explore patients' knowledge, attitude, and practice (KAP) toward varicocele in China the relationship between treatment selection KAP.
Alterations in life forms could simultaneously influence the variability of fine root and leaf traits. However, our understanding organ-level coordination patterns variation traits among desert herbs shrubs with distinct habits remains limited.
PI3KCA and mutant p53 are associated with tumorigenesis the development of cancers. NVP-BKM120, a selective pan-PI3K inhibitor, exerts antitumor activity by suppressing PI3K signaling pathway. Prima-1Met, low molecular weight compound, can rescue gain-of-function restoring its transcriptional function. In this study, we investigated whether inhibition combined reactivation could enhance effect in thyroid cancer cells.The effects BKM120 Prima-1Met on proliferation, apoptosis, migration...
Taxus mairei is an important source for industrial extraction of taxol in China. However, the standard and steps are currently not uniform, which seriously affects yield. In present study, influence four factors (methanol concentration, solid-liquid ratio, ultrasonic temperature, time) on yield was successively explored T. mairei. A response surface methodology (RSM) used to optimize process based single-factor experiments above. The optimal conditions were as follows: methanol concentration...
Gastric cancer (GC) has high rates of morbidity and mortality, this phenomenon is particularly evident in coastal regions where local dietary habits favor the consumption pickled foods such as salted fish vegetables. In addition, diagnosis rate GC remains low due to lack diagnostic serum biomarkers. Therefore, study, we aimed identify potential biomarkers for use clinical practice. To candidate GC, 88 samples were first screened using a high-throughput protein microarray measure levels 640...
Fine root traits embody trade-offs between resource acquisition and conservation in plants. Yet, the differentiation of these across orders, existence a economics spectrum (RES) spanning their linkage with leaf remain underexplored. In this study, we analyzed first three orders 15 co-occurring plant species, including ten herbs five shrubs, from desert–oasis transition zone Hexi Corridor. We measured twelve morphological chemical to investigate relationships traits. Our results revealed...
Abstract Perpose: Pancreatic cancer has a poor prognosis and is considered one of the most lethal tumors. ITGA2, gene highly expressed in various tumor tissues, promising candidate for therapy. The objective this study to assess presence MET PD-L1 pancreatic cancer, while also identifying CD4 CD8 as potential survival indicators patients suffering from disease. Experimental Design: We examined expression MET, E-cad, PD-L1, CD4, proteins 62 tissue samples using multi-tissue immunofluorescence...
Objective To analyze and evaluate the association between platelet to lymphocyte ratio(PLR), neutrophil ratio (NLR) early castration-resistant prostate cancer(CRPC) patients after androgen deprivation therapy. Methods Clinical data of 305 with cancer January 2009 December 2013 were retrospectively analyzed. All underwent biopsy diagnosed by pathological examination. Based on PLR NLR, assigned into high group, low NLR group. Clinical features including tPSA, mGPS, clinical stage,...
Objective To investigate the expressions of phosphatase and tensin homologue deleted on chromosome ten (PTEN) epithelial cadherin (E-cadherin) in breast cancer tissues explore their clinical significance. Methods We retrospectively analyzed data 263 patients admitted to First Affiliated Hospital Harbin Medical University from November 2012 December 2014. The PTEN E-cadherin were detected by immunohistochemistry. relationship protein expression with clinicopathological characteristics...