A5039361481- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Thermal Regulation in Medicine
- Cardiac Arrest and Resuscitation
- Congenital Diaphragmatic Hernia Studies
- Family and Patient Care in Intensive Care Units
- Cell Adhesion Molecules Research
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Healthcare Decision-Making and Restraints
- Tracheal and airway disorders
- Nail Diseases and Treatments
- Pain Management and Placebo Effect
- Mechanical Circulatory Support Devices
- COVID-19 Clinical Research Studies
- Ear and Head Tumors
- Enhanced Recovery After Surgery
- Long-Term Effects of COVID-19
- Growth Hormone and Insulin-like Growth Factors
- Music Therapy and Health
- Non-Invasive Vital Sign Monitoring
- Thyroid Disorders and Treatments
- Polyamine Metabolism and Applications
Kagawa University
2024-2025
Osaka University
2017-2025
Osaka University Hospital
2014-2024
Fukuda Foundation for Medical Technology
2023
Ministry of Education, Culture, Sports, Science and Technology
2023
Toshima Hospital
2021
Osaka International Cancer Institute
2019
Shiga University of Medical Science
2018
Okayama University Hospital
1998
Okayama University
1998
In acute respiratory distress syndrome (ARDS), atelectatic solid-like lung tissue impairs transmission of negative swings in pleural pressure (Ppl) that result from diaphragmatic contraction. The localization more Ppl proportionally increases dependent stretch by drawing gas either other regions (e.g., nondependent [pendelluft]) or the ventilator. Lowering level spontaneous effort and/or converting to fluid-like might render noninjurious.To determine whether injury, and such injury would be...
Rationale: Spontaneous breathing during mechanical ventilation increases transpulmonary pressure and Vt, worsens lung injury. Intuitively, controlling Vt might limit injury caused by added spontaneous effort.Objectives: To test the hypothesis that, effort in injured lungs, limitation of volume-controlled results less injurious patterns inflation.Methods: Dynamic computed tomography was used to determine regional inflation rabbits with lungs or pressure-controlled ventilation. Transpulmonary...
General anesthesia and mechanical ventilation have negative impacts on the respiratory system, causing heterogeneous distribution of lung aeration, but little is known about patterns postoperative patients their association with clinical outcomes.
Patient-ventilator asynchrony is often observed during mechanical ventilation and associated with higher mortality. We hypothesized that patient-ventilator causes lung diaphragm injury dysfunction.Prospective randomized animal study.University research laboratory.Eighteen New Zealand White rabbits.Acute respiratory distress syndrome (ARDS) model was established by depleting surfactants. Each group (assist control, breath stacking, reverse triggering) simulated phrenic nerve stimulation. The...
Polypectomy-associated bleeding is the most frequent complication of colorectal polypectomy. An 82-year-old woman underwent polypectomy after an endoloop was placed in a pedunculated polyp sigmoid colon. However, dislodged, causing massive from stem surface. Furthermore, vessel could not be identified because narrow resection surface and presence thrombus hemorrhage. Therefore, several clips were removed, performed again on to open wider identify vessels. Finally, responsible arterial...
Abstract Background Postoperative patients constitute majority of critically ill patients, although factors predicting extubation failure in this group remain unidentified. Aiming to propose clinical predictors reintubation postoperative we conducted a post-hoc analysis multicenter prospective observational study. Methods This study included who underwent mechanical ventilation for > 24 h and were extubated after successful 30-min spontaneous breathing trial. The primary outcome was...
Heterogeneity is an inherent nature of ARDS. Recruitment-to-inflation ratio has been developed to identify the patients who lung recruitablity. This technique might be useful that match specific interventions, such as higher positive end-expiratory pressure (PEEP) or prone position both. We aimed evaluate physiological effects PEEP and body on mechanics regional inflation in COVID-19-associated ARDS propose optimal ventilatory strategy based recruitment-to-inflation ratio.Patients with were...
Abstract Background Reintubation is a common complication in critically ill patients requiring mechanical ventilation. Although reintubation has been demonstrated to be associated with patient outcomes, its time definition varies widely among guidelines and the literature. This study aimed determine association between outcomes as well consequences of elapsed extubation on outcomes. Methods was multicenter retrospective cohort conducted April 2015 March 2021. Adult who underwent ventilation...
Maximal inspiratory pressure (MIP) is used to assess respiratory muscle strength of patients with myasthenia gravis (MG) requiring ventilatory support. Electrical activity the diaphragm (E-di) has been guide weaning. The MIP and tidal volume/ΔE-di (the patient-to-ventilator breath contribution) were monitored in a 12-year-old girl MG ventilator same settings maintained until extubation. During weaning, increased slightly, but varied unpredictably. Tidal decreased at constant rate as...
The cuff leak test (CLT) has been widely accepted as a simple and noninvasive method for predicting post-extubation stridor (PES). However, its accuracy clinical impact remain uncertain. We aimed to evaluate the reliability of CLT assess pre-extubation variables on incidence PES. A prospective observational study was performed adult critically ill patients who required mechanical ventilation more than 24 h. Patients were extubated after successful spontaneous breathing trial, conducted...
Abstract Background Extracorporeal membrane oxygenation (ECMO) is an integral method of life support in critically ill patients with severe cardiopulmonary failure; however, such generally require prolonged mechanical ventilation and exhibit high mortality rates. Tracheostomy commonly performed on ventilation, its early implementation has potential advantages for favorable patient outcomes. This study aimed to investigate the association between tracheostomy timing outcomes, including...
<h3>BACKGROUND:</h3> Faster inspiratory pressurization can improve patient–ventilator synchrony and reduce the patient9s work of breathing during pressure controlled continuous mandatory (PC-CMV) ventilation. The characteristics ramp settings are not standardized across ventilators from different manufacturers. We performed a bench test 5 models ICU to examine effects on actual pressurization. <h3>METHODS:</h3> A twin-bellows lung model was used, in which one bellow simulates muscle activity...
Due to the coronavirus disease 2019 pandemic, number of 2019-associated acute respiratory distress syndrome is rapidly increasing. The heterogeneity contributes complexity managing patients. Here we described two patients with showing that bedside physiological approach including careful evaluation system mechanics and visualization ventilation electrical impedance tomography was useful individualize ventilatory management.
肝炎スクリーニング検査で判明した肝炎ウイルス感染者が適切に院内連携できているかは明らかではない.屋島総合病院では2018年4月から肝炎医療コーディネーターが中心となった多職種で構成された「チーム肝炎」にて患者を拾い上げ,紹介を促すスキームを構築した.「チーム肝炎」から肝炎ウイルス結果説明文を渡し,陽性患者に対して「チーム肝炎」から肝臓専門医への紹介可能にした.2017と2018年度の非専門他科から消化器/肝臓内科へのHCV抗体陽性患者の紹介率は15から83.1%,HBs抗原陽性患者は38.9から91.6%と介入にて紹介率が上昇した.また,2017年度と2018年度の新規B型肝炎患者のフォロー数は9から19例,直接作用型抗ウイルス薬の導入数は8から25例と増加した.当院のスキームによるウイルス肝炎患者の拾い上げは,院内連携,専門医によるフォローアップや治療につながると考えられる.
Although post-gastric endoscopic submucosal dissection (ESD) bleeding is reduced by defect closure [1] [2] [3], there no convenient and secure mucosal inverted method that enables early wound healing through sustained closure. We previously reported on post-ESD using jumbo grasping forceps (FG-47L-1; Olympus, Tokyo, Japan) [4]; however, one problem was the poor maneuverability of forceps. Subsequently, we used EndoGrip (EndoGrip, AG-5039-2323; AGS MedTech, ([Fig. 1]), which allows while...
How to cite this article: Tanaka A, Yamashita T, Koyama Y, Uchiyama Fujino Y. Predictors of Successful Extubation in Reintubated Patients: The Impact Fluid Balance during the 24 Hours Prior Extubation. Indian J Crit Care Med 2019;23(7):344-345.
<h3>BACKGROUND:</h3> Prone positioning and neuromuscular blocking agents (NMBAs) are frequently used to treat severe respiratory failure from COVID-19 pneumonia. has shown improve mortality, whereas NMBAs prevent ventilator asynchrony reduce patient self-inflicted lung injury. However, despite the use of lung-protective strategies, high death rates in this population have been reported. <h3>METHODS:</h3> We retrospectively examined factors affecting prolonged mechanical ventilation subjects...
Backgroud and Objective: Antithyroid drugs (ATDs) [methylmercaptoimidazole (MMI) propylthiouracil (PTU) ] are used to treat hyperthyroidism in Graves' disease. The effect of ATDs reducing agents (mercaptoethanol, dithiothreitol cysteine) on bovine (b) TSH binding human (h) porcine (p) receptor (R) was examined.(1) pre-incubated with hTSHR coated tube for 1- 4 h, washed free ATDs, then 125I-bTSH after 1 h incubation examined. MMI (10-40 mM) decreased a dose-dependent manner proportionally as...
In all endoscopic ultrasound (EUS) examinations performed at our hospital, the heart, vasculature, and mediastinal lymph nodes from esophagus are observed after checking for gastrointestinal pathologies. Since introduction of EUS using a convex linear-array echoendoscope hospital in April 2015, have been 371 cases examining pancreaticobiliary diseases, submucosal tumors, other pathologies during 3-year period, till March 2018. We diagnosed 2 patients with asymptomatic cardiovascular disease...