- Renal Diseases and Glomerulopathies
- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Erythropoietin and Anemia Treatment
- Liver Diseases and Immunity
- Urticaria and Related Conditions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Iron Metabolism and Disorders
- Diabetes Management and Research
- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Sarcoidosis and Beryllium Toxicity Research
- Metabolism and Genetic Disorders
- Dermatological and Skeletal Disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Genetic Associations and Epidemiology
- Parathyroid Disorders and Treatments
- Immunotherapy and Immune Responses
- Pregnancy and preeclampsia studies
- T-cell and B-cell Immunology
- Neurological Complications and Syndromes
- Reproductive System and Pregnancy
- Otitis Media and Relapsing Polychondritis
- Pregnancy and Medication Impact
Gdańsk Medical University
2009-2024
Medical University of Białystok
2021
<b>Introduction</b>: Granulomatosis with polyangiitis (GPA) is a rare, ANCA-associated, systemic disease characterized by necrotizing small and medium vessel vasculitis of unknown etiology associated granulomatous inflammation affecting the renal, pulmonary, upper airways, ocular systems other tissues. Histological proof granulomatosis can be obtained biopsy clinically involved sites. The main purpose this study was to examine histopathological changes in non-renal biopsies from...
Systemic lupus erythematosus (SLE) is a serious autoimmune disease with variety of organ manifestations. The most dreadful one, affecting the majority SLE patients, kidney manifestation – nephritis (LN). Dendritic cells (DC) are believed to be one culprits immune dysregulation in LN. Flow cytometry analysis was applied identify frequency and activity peripheral blood DCs subpopulations: myeloid plasmacytoid, LN patients. Magnetically isolated mDCs pDCs were subjected molecular genes...
Longer life expectancy is associated with an increasing prevalence of kidney disease. Aging itself may cause renal damage, but the spectrum disorders that affect elderly patients diverse. Few studies, mostly form US, Asia and West Europe found differences in some types diseases between younger based on biopsy findings, varied proportion glomerulopathies arterionephrosclerosis as a dominant injury found. Here, for first time Eastern we analyzed native findings their relationship to clinical...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Masiak A, Zdrojewski Ł, Z, Bułło-Piontecka B, Rutkowski B. Gastrointestinal tract involvement in granulomatosis with polyangiitis. Gastroenterology Review/Przegląd Gastroenterologiczny. 2016;11(4):270-275. doi:10.5114/pg.2016.57887. APA Masiak, A., Zdrojewski, Ł., Z., Bułło-Piontecka, B., & Rutkowski, (2016). Gastroenterologiczny, 11(4), 270-275. https://doi.org/10.5114/pg.2016.57887 Chicago Anna, Łukasz...
Systemic lupus erythematosus (SLE) is one of the autoimmune diseases, believed to be closely related hyperactivity B cells, overproduction autoantibodies and immune complex formation deposition in affected tissue. The autoreactive inflammation leads multiorgan damage with kidney dysfunction forefront. Studies on nephritis (LN), affecting majority SLE patients, are mainly focused cells causing local inflammation. aim our work was detect alterations more accessible peripheral blood course...
To characterize the eosinophilic granulomatosis with polyangiitis (EGPA) population from POLVAS registry depending on ANCA status and diagnosis onset, including their comparison (GPA) subset elevated blood eosinophilia (min. 400/
Abstract: Impaired immunological response in hemodialysis (HD) patients, which leads to inappropriate cytokine production, is partially caused by the hyperstimulation of both T lymphocytes and monocytes/macrophages. Recent data suggest that human recombinant erythropoietin (rhEPO) may have an action. The goal our study was estimate influence rhEPO treatment on production inflammatory tumor necrosis factor α (TNFα) antiinflammatory cytokin interleukin‐10 (IL‐10) 10 HD patients receiving for 6...
Abstract: The impairment of function human T lymphocytes, leading to an inappropriate cytokine production, is partially responsible for defective immunological response in hemodialysis patients (HD). Recent data suggest that recombinant erythropoietin (rhEPO) may exert effects. aim this study was find out whether rhEPO treatment the HD have effect on interleukin 2 (IL‐2) production by their whole blood cell cultures. carried 10 receiving 6 months. Compared with levels seen before treatment,...
Antineutrophil cytoplasmic antibody-associated vasculitides (AAV) is a group of systemic necrotizing small vessel autoimmune diseases, with microscopic polyangiitis (MPA) and granulomatosis (GPA) being the two most common. The co-existence AAV different immune-mediated diseases (autoimmune disesases - AID) might affect clinical presentation primary disease. purpose study was to assess AID investigate whether it affects characteristics course AAV.
Antiphospholipid syndrome (APS) is a devastating autoimmune disease and in renal transplant recipients may result allograft thrombosis or extra-renal manifestation, mostly venous thromboembolism. There are many non- immune risk factors affecting with APS. However, outcome APS without nephropathy remains unknown. Aim: The aim of the study was to assess function survival Methods: Retrospective, multicenter included 19 adult definite (primary lupus-related) from three Polish centers. Renal...
Abstract Phantoms of biological tissues are materials that mimic the properties real tissues. This study shows development phantoms with nanodiamond particles for calibration T1 relaxation time in magnetic resonance imaging. Magnetic imaging (MRI) is a commonly used and non-invasive method detecting pathological changes inside human body. Nevertheless, before new MRI device approved use, it necessary to calibrate properly check its technical parameters. In this article, we present tissue...
Abstract In this paper, a spectroscopic method for determination of cyclosporine concentrations in biological fluids is presented. Blood plasma and hemoglobin solutions are chosen the experiment. For various blood hemoglobin, absorbance measurements spectra range from 600 to 1100 nm performed. The measurement results analyzed by use dedicated algorithm. obtained data characterized high coefficient correlation R 2 , which equal 0.9461 0.9808 respectively. proposed enables selective detection...
Systemic lupus erythematosus (SLE) patients have an increased risk of infections and infection-related mortality. Therefore, during the global SARS-CoV-2 pandemic, SLE were particularly vulnerable to infections. Also, compared other patients, seem develop more severe manifestations coronavirus disease 2019 (COVID-19), with higher rates hospitalization, invasive ventilation requirements, or death. This study evaluated immune parameters after infection in patients. We analyzed subpopulations...